Mechanistic links between diet, lipid metabolism, and tumor growth and progression (U01 Clinical Trial Not Allowed)

Closed Posted

Opportunity number
PAR-25-119
Agency
Applications due
Award size
Not on record

Opportunity facts

Funding instrument
Cooperative Agreement
Categories
  • Education
  • Health
Eligible applicants
  • Special District Governments
  • For Profit Organizations
  • County Governments
  • City/Township Governments
  • Non-501(c)(3) Nonprofits
  • Independent School Districts
  • 501(c)(3) Nonprofits
  • Other
  • State Governments
  • Small Businesses
  • Tribal Organizations (Not Federally Recognized)
  • Tribal Governments (Federally Recognized)
  • Public or Indian Housing Auth.
  • Higher Education Inst. (Private)
  • Higher Education Inst. (Public)
Points of contact
Full announcement

Opportunity details come from Grants.gov. Updated .

About this opportunity

Written by GovTribe AI ·

The National Institutes of Health (NIH) is seeking research applications investigating the mechanistic links between diet, lipid metabolism, and tumor growth and progression through a Cooperative Agreement funding mechanism. This Notice of Funding Opportunity (NOFO) aims to support fundamental studies that identify and define molecular mechanisms through which lipid metabolism mediates tumor growth, with a specific focus on understanding the central role of lipids in connecting diet with cancer biology. The research should bridge historically divided fields of nutrition and molecular metabolism and stimulate research and tool development in this complex area of lipid biochemistry. Applicants will be evaluated based on scientific merit, including the significance of study objectives, technical adequacy of experimental design, investigator competency, available facilities and resources, budget appropriateness, and relevance to program objectives. The grant opportunity is open to a wide range of applicant types, including academic institutions, nonprofits, small businesses, and government entities, with a posted date of October 30, 2024, and a response deadline of December 9, 2025.

While specific award amounts are not detailed in the documentation, the grant will be awarded as a Cooperative Agreement through the Department of Health and Human Services National Institutes of Health. The research will be conducted at the recipient's facilities across the United States, with typical project periods spanning 2-5 years. This grant opportunity is part of multiple cancer-related research programs, including Cancer Detection and Diagnosis Research, Cancer Treatment Research, Cancer Cause and Prevention Research, Cancer Control, and Cancer Biology Research. The research is expected to be performed domestically and will undergo rigorous scientific peer review to assess its technical merit, potential for commercial application, and alignment with program goals.

Synopsis

Through this Notice of Funding Opportunity (NOFO) is to request applications that propose mechanistic investigations of the links between diet, lipid metabolism and tumor growth and progression. It is anticipated that this program will support fundamental studies designed to identify and define the molecular mechanisms through which lipid metabolism mediates tumor growth and progression, focusing specifically on the central role lipids play in linking diet with the biology of cancer; bridge the historically divided fields of nutrition and molecular metabolism; and stimulate research and tool development in this emerging area, which faces particular challenges because of the complexity of lipid biochemistry.

Files

File Type Posted
PAR-25-119-Full-Announcement.html HTML file

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