Mechanisms Underlying Olfactory Dysfunction in Aging and Alzheimer's Disease and Alzheimer's Disease-Related Dementias
Past Federal grant forecast Posted
- Opportunity number
- RFA-AG-26-021
- Agency
-
National Institutes of Health
Department of Health and Human Services
- Applications expected due
- Award size
- Not on record
Opportunity facts
- Expected posting
- Assistance listings
-
- 93.866 Aging Research
- Funding instrument
- Grant
- Category
-
- Health
- Eligible applicants
-
- 501(c)(3) Nonprofits
- Other
- State Governments
- Non-501(c)(3) Nonprofits
- Small Businesses
- Special District Governments
- Higher Education Inst. (Private)
- For Profit Organizations
- County Governments
- Tribal Organizations (Not Federally Recognized)
- Public or Indian Housing Auth.
- Independent School Districts
- City/Township Governments
- Tribal Governments (Federally Recognized)
- Higher Education Inst. (Public)
- Points of contact
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- Coryse St. Hillaire-Clarke sthillaireclacn@mail.nih.gov (301) 496-9350
Opportunity details come from Grants.gov. Updated .
About this opportunity
The National Institute on Aging (NIA), with the National Institute on Deafness and Other Communication Disorders (NIDCD), intends to publish a Notice of Funding Opportunity to solicit R01 applications investigating the mechanisms underlying the association between olfactory decline and aging or Alzheimer's disease and Alzheimer's disease-related dementias; applications are not currently being solicited, and no hard deadline is specified. This is a forecast to allow potential applicants time to develop collaborations and responsive projects.
Eligible applicant categories include 501(c)(3) nonprofits, public and private higher education institutions, state and local governments, tribal organizations (both federally recognized and non-federally recognized), small businesses, for-profit organizations, faith-based and community-based organizations, and other entities. The NIA Aging Research program (CFDA 93.866) does not require cost share.
Research may include older adults and animal models employing cellular, molecular, imaging, physiological, omics, and new approach methodologies to address research gaps. Studies should investigate how olfactory dysfunction may serve as an indicator of health outcomes in older adults (such as physical function) and as a predictor of AD/ADRD risk, and identify circuit-level olfactory changes that could uncover novel therapeutic targets.
Evaluation focuses on scientific merit, general significance of proposed study objectives, technical adequacy of experimental design, investigator competency, facility and resource adequacy, budget necessity relative to project scope, and relevance to program objectives. The Aging Research program typically awards individual grants for three to five years with review timelines of six to nine months from application to funding decision. Standard NIH record retention requirements apply for three years from annual FSR submission.
Forecast synopsis
The National Institute on Aging (NIA), with the National Institute on Deafness and Other Communication Disorders (NIDCD), intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications that investigate the mechanisms underlying the association between olfactory decline and aging or Alzheimer's disease (AD) and AD-related dementias (ADRD). Understanding these mechanisms may help inform the potential use of olfactory dysfunction with age as an indicator of various health outcomes in older adults (e.g. physical function) and as a predictor of AD/ADRD risk. Identifying circuit-level olfactory changes may also uncover novel targets for developing disease-modifying therapeutic strategies. Studies may include older adults and/or animal models and may employ a variety of approaches, including cellular, molecular, imaging, physiological, omics and new approach methodologies (NAMs) to address the research gaps.
Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO intends to utilize the R01 activity code. Investigators with expertise and insights into this area of aging research are encouraged to begin to consider applying for this new NOFO.
Eligibility
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations.
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