Limited Competition: Small Grant Program for NHLBI K01/K08/K23/K25 Recipients (R03 Clinical Trial Optional)
Open Posted
- Opportunity number
- RFA-HL-27-004
- Agency
-
National Institutes of Health
Department of Health and Human Services
- Applications due
- Award size
- Up to $85,000
Opportunity facts
- Assistance listings
- Funding instrument
- Grant
- Category
-
- Health
- Eligible applicants
-
- City/Township Governments
- Tribal Governments (Federally Recognized)
- Non-501(c)(3) Nonprofits
- 501(c)(3) Nonprofits
- Small Businesses
- County Governments
- For Profit Organizations
- State Governments
- Independent School Districts
- Higher Education Inst. (Public)
- Higher Education Inst. (Private)
- Other
- Special District Governments
- Public or Indian Housing Auth.
- Tribal Organizations (Not Federally Recognized)
- Points of contact
Opportunity details come from Grants.gov. Updated .
About this opportunity
The National Heart, Lung, and Blood Institute (NHLBI) is soliciting applications from current or recently completed NHLBI K01, K08, K23, and K25 career development awardees for small grant support (R03), with an application due date of November 7, 2028. This is a limited competition restricted to K awardees only; foreign organizations and non-domestic components of U.S. organizations are not eligible.
Current K awardees may apply starting in the third year of their K award project period. Recently completed K awardees are eligible to apply or resubmit A1 applications if the earliest potential R03 award start date is within two years of their K award project period end date. Applicants must maintain a minimum of 40% protected research effort during the R03 award period through a combination of effort on the proposed R03 project and other research projects, irrespective of funding source. For current and former K23 awardees, the research proposed may or may not include patient-oriented research.
The R03 mechanism supports research projects completed within two years using limited resources, including pilot or feasibility studies, proof-of-concept studies, secondary analysis of existing data, small self-contained research projects, and development of new research methodologies or technologies. Award budgets are limited to direct costs of $85,000 per year for a maximum two-year project period. NHLBI intends to commit $3.9 million in FY2027, $7.8 million in FY2028 and FY2029, and $3.9 million in FY2030, funding approximately 29 new awards annually through FY2029.
The program objective is to facilitate transition to research independence by generating critical preliminary data and publications to support subsequent R01-equivalent applications. Review emphasizes research significance and innovation, rigor and feasibility, investigator expertise and institutional resources, and trajectory toward research independence. Scientific merit review occurs through the Center for Scientific Review with secondary review by the National Heart, Lung, and Blood Advisory Council. The NOFO was updated per NOT-HL-26-010. Assistance Listing 93.837 (Cardiovascular Diseases Research) applies.
Synopsis
This is a Notice of Funding Opportunity (NOFO) for a Limited Competition that invites applications from eligible organizations to apply. Please see Section III. Eligibility for additional information. In accordance with NIH standard peer-review processes, the applications will be peer-reviewed, and only meritorious applications will be considered. The purpose of this NOFO is to solicit current or recently completed NHLBI K01, K08, K23, and K25 awardees for small grant support to expand their current research objectives or to branch out to a new study emerging from their K award research. This NOFO is intended to facilitate the transition to research independence for these NHLBI K awardees. Current NHLBI K01, K08, K23, and K25 awardees may apply for this R03 support starting in the third year of their K award Project Period. Recently completed NHLBI K01, K08, K23, and K25 award recipients are eligible to apply or resubmit A1 applications if the earliest potential R03 award start date is within two years of the end of their K award Project Period.The R03 grant mechanism supports research projects that can be completed within two years and with limited resources. These projects are expected to generate preliminary data to bolster a subsequent R01-equivalent application. Eligible projects include, but are not limited to, pilot or feasibility studies; proof of concept studies; secondary analysis of existing data; small, self-contained research projects; development of new research methodologies or technologies, or creation of novel experimental model systems.Applicants are required to maintain a minimum of 40% protected research effort during the R03 award period. This requirement can be fulfilled through a combination of effort on the proposed R03 project and other research projects, irrespective of funding source.For current and former K23 awardees, the research proposed in the R03 application may or may not include patient-oriented research.
Eligibility
Only the following NHLBI K01, K08, K23, and K25 awardees are eligible to apply for this funding opportunity.Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
Files
| File | Type | Posted |
|---|---|---|
| RFA-HL-27-004-Revised-Full-Announcement.html | HTML file | |
| RFA-HL-27-004-Revised-Full-Announcement.html | HTML file | |
| PKG00292765.pdf |
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