Limited Competition for the Continuation of the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) Data Analysis Resource (U24 Clinical Trials Optional)
Past Federal grant forecast Posted
- Opportunity number
- NOT-AA-25-014
- Agency
-
National Institutes of Health
Department of Health and Human Services
- Applications expected due
- Award size
- Not on record
Opportunity facts
- Expected posting
- Assistance listings
-
- 93.273 Alcohol Research Programs
- Funding instrument
- Cooperative Agreement
- Category
-
- Health
- Eligible applicants
-
- Tribal Organizations (Not Federally Recognized)
- Tribal Governments (Federally Recognized)
- State Governments
- Public or Indian Housing Auth.
- Higher Education Inst. (Public)
- Small Businesses
- Higher Education Inst. (Private)
- Independent School Districts
- 501(c)(3) Nonprofits
- For Profit Organizations
- County Governments
- Points of contact
-
- Dominique Lorang-Leins lorangd@mail.nih.gov (301) 594-6228
Opportunity details come from Grants.gov. Updated .
About this opportunity
The National Institute on Alcohol Abuse and Alcoholism (NIAAA) is forecasting a limited-competition cooperative agreement to continue funding the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) Data Analysis Resource using the U24 activity code; applications are not currently being solicited, but notice is provided to allow development of collaborations. This is a restricted competition limited to the incumbent NCANDA consortium, not an open solicitation.
Eligible applicants include higher education institutions (public and private), state and county governments, tribal governments (federally recognized and not federally recognized), 501(c)(3) nonprofits, for-profit organizations, small businesses, public or Indian housing authorities, and independent school districts. Cost share and award amount details are not specified in this forecast notice.
NCANDA has followed over 800 participants longitudinally from ages 12 to 32 since its 2012 launch, tracking adolescent alcohol exposure and its effects on brain structure, function, and psychiatric health through emerging adulthood. The renewal will extend participant follow-up to age 37, generating data on how early versus late adolescent drinking onset differentially impacts adult drinking behavior and the trajectory to alcohol use disorder. This dataset addresses a gap in the literature, as existing adult drinking studies lack pre-drinking baseline measurements across the critical developmental window.
The program prioritizes generating evidence for alcohol prevention strategies and early intervention approaches to reduce progression to severe drinking and chronic disease. NCANDA operates under Assistance Listing 93.273 (Alcohol Research Programs). The forecast provides potential applicants time to prepare proposals; a formal NOFO with application deadlines and budget parameters will follow.
Forecast synopsis
The National Institute on Alcohol Abuse and Alcoholism (NIAAA) launched the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) in 2012 to determine how adolescent alcohol-related disruption of normal brain growth patterns of structure, related brain function, and psychiatric health affects brain functioning in emerging adulthood. The consortium uses an accelerated longitudinal design and has acquired data on over 800 individuals between the ages of 12 to 32 years. This wide age range covers the period before onset of drinking, the transition from adolescence to young adulthood, the critical period for binge drinking, and the time of maturing out. This unique dataset provides novel information on the enduring and transient consequences of adolescent drinking on adult brain function and behavior. Current studies on adults drinking do not have this type of data. Renewal of this limited competition NOFO will enable NCANDA to continue to follow these participants up to 37 years of age and acquire data critical to understanding how early versus late onset drinking during adolescence differentially impacts drinking behavior in adulthood. This limited competition renewal will provide valuable information for developing evidence-based alcohol prevention strategies and early intervention approaches to prevent the progression to more severe drinking and AUD thereby preventing the development of chronic disease, improving health outcomes, and increasing quality of life and longevity. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the U24 activity code. Investigators with expertise and insights into this area of integrative neuroscience are encouraged to begin to consider applying for this new NOFO.
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