Limited Competition for the Continuation of the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) Administrative Resource (U24 Clinical Trials Optional)

Past Federal grant forecast Posted

Opportunity number
NOT-AA-25-013
Agency
Applications expected due
Award size
Not on record

Opportunity facts

Expected posting
Assistance listings
Funding instrument
Cooperative Agreement
Category
  • Health
Eligible applicants
  • Small Businesses
  • Higher Education Inst. (Private)
  • Independent School Districts
  • 501(c)(3) Nonprofits
  • For Profit Organizations
  • County Governments
  • Tribal Organizations (Not Federally Recognized)
  • Tribal Governments (Federally Recognized)
  • State Governments
  • Public or Indian Housing Auth.
  • Higher Education Inst. (Public)
Points of contact

Opportunity details come from Grants.gov. Updated .

About this opportunity

The National Institute on Alcohol Abuse and Alcoholism (NIAAA) is forecasting a limited competition cooperative agreement to continue administrative operations of the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA); applications are not being solicited at this time, but notice is provided to allow potential applicants to develop meaningful collaborations. This is a continuation award under the U24 activity code, using Assistance Listing 93.273 (Alcohol Research Programs).

NCANDA, established in 2012, has enrolled over 800 participants aged 12 to 32 years and tracks the longitudinal effects of adolescent alcohol exposure on brain structure, function, and psychiatric outcomes into emerging adulthood. The renewal will extend follow-up to age 37 and acquire data differentiating early versus late onset adolescent drinking on adult drinking behavior and alcohol use disorder risk. This dataset is unique in covering the pre-drinking period, the adolescent-to-adulthood transition, the critical window for binge drinking escalation, and the age of "maturing out," providing evidence to support prevention strategies and early intervention approaches.

Eligible applicants include higher education institutions (public and private), nonprofits organized as 501(c)(3)s, state and tribal governments (federally recognized and not federally recognized), county governments, small businesses, for-profit organizations, independent school districts, and public or Indian housing authorities.

The consortium seeks investigators with expertise in developmental neuroscience. The renewal aims to prevent progression to severe drinking and alcohol use disorder, thereby preventing chronic disease, improving health outcomes, and increasing quality of life and longevity. No specific funding amount, award timeline, or period of performance is disclosed in this forecast notice.

Forecast synopsis

The National Institute on Alcohol Abuse and Alcoholism (NIAAA) launched the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) in 2012 to determine how adolescent alcohol-related disruption of normal brain growth patterns of structure, related brain function, and psychiatric health affects brain functioning in emerging adulthood. The consortium uses an accelerated longitudinal design and has acquired data on over 800 individuals between the ages of 12 to 32 years. This wide age range covers the period before onset of drinking, the transition from adolescence to young adulthood, the critical period for binge drinking, and the time of maturing out. This unique dataset provides novel information on the enduring and transient consequences of adolescent drinking on adult brain function and behavior. Current studies on adults drinking do not have this type of data. Renewal of this limited competition NOFO will enable NCANDA to continue to follow these participants up to 37 years of age and acquire data critical to understanding how early versus late onset drinking during adolescence differentially impacts drinking behavior in adulthood. This limited competition renewal will provide valuable information for developing evidence-based alcohol prevention strategies and early intervention approaches to prevent the progression to more severe drinking and AUD thereby preventing the development of chronic disease, improving health outcomes, and increasing quality of life and longevity. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the U24 activity code. Investigators with expertise and insights into this area of developmental neuroscience are encouraged to begin to consider applying for this new NOFO.

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