Limited Competition: Chronic Kidney Diseases of UnceRtain Etiology (CKDu) in Agricultural Communities (CURE) Research Consortium- Field Epidemiology Sites
Past Federal grant forecast Posted
- Opportunity number
- RFA-DK-27-130
- Agency
-
National Institutes of Health
Department of Health and Human Services
- Applications expected due
- Award size
- Not on record
Opportunity facts
- Expected posting
- Assistance listings
- Funding instrument
- Cooperative Agreement
- Category
-
- Health
- Eligible applicants
-
- Tribal Governments (Federally Recognized)
- County Governments
- Higher Education Inst. (Private)
- State Governments
- Small Businesses
- Other
- Higher Education Inst. (Public)
- Tribal Organizations (Not Federally Recognized)
- For Profit Organizations
- Public or Indian Housing Auth.
- Points of contact
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- Susan Mendley susan.mendley@nih.gov (301) 827-1861
Opportunity details come from Grants.gov. Updated .
About this opportunity
The National Institutes of Health is soliciting renewal applications for Field Epidemiology Sites within the Consortium to Study Chronic Kidney Disease of Uncertain Etiology (CKDu) in Agricultural Communities (CURE) under a limited competition cooperative agreement; this is a forecast announcement with no hard deadline stated. The funding opportunity is open to tribal governments (federally and non-federally recognized), county and state governments, higher education institutions (public and private), small businesses, for-profit organizations, public or Indian housing authorities, federal agencies, U.S. territories or possessions, faith-based or community-based organizations, regional organizations, and non-domestic entities.
Field Epidemiology Sites will identify, recruit, and retain participants in CKDu endemic areas, conduct study visits, and collect biological and environmental samples to support consortium-wide discovery science on disease etiology, environmental exposures, tubulointerstitial kidney disease progression, therapeutic targets, and public health interventions. The CURE Consortium, jointly funded by NIDDK, NIEHS, and FIC since 2021, includes Field Epidemiology Sites, a Renal and Environmental Science Core, and a Data Coordinating Center. The consortium will serve as a resource for ancillary studies. Research addresses CKDu's impact in rural areas of Low and Middle Income Countries and identifies risk factors encountered in U.S. patients, with implications for understanding kidney health and disease domestically.
Applications will undergo peer review and funding is contingent on scientific merit. The opportunity is assigned to the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). Cost share, award ceiling, award floor, and period of performance details are not specified in this forecast announcement.
Forecast synopsis
The purpose of this funding opportunity is to advance the NIH mission by supporting the continuation of the Consortium to Study Chronic Kidney Disease of UnceRtain Etiology (CKDu) in Agricultural Communities (CURE).
Chronic Kidney Disease of Uncertain Etiology (CKDu) causes kidney failure in rural areas of many Low and Middle Income Countries, resulting in a large death toll among the young working age population. Environmental factors are suspected to be causative, but family and geographic clustering add consideration of unrecognized genetic susceptibility. The risk factors identified in other countries are encountered by U.S. patients, so this research will offer valuable insights into the development and progression of tubulointerstitial renal diseases, with broad implications for understanding kidney health and disease in the U.S.
NIDDK, NIEHS, and FIC have jointly funded a consortium that includes Field Epidemiology Sites, a Renal and Environmental Science Core, and a Data Coordinating Center to find causes and potential interventions for CKDu since 2021. This NOFO requests renewal applications for the Field Epidemiology Sites that will continue to identify, recruit, and retain participants in CKDu endemic areas, conduct study visits, and collect biological and environmental samples. Consortium members will continue to collaborate to maximize scientific opportunities and enable discovery science to understand the etiologies of CKDu, the exposures that initiate and affect progression of tubulointerstitial kidney disease, potential therapeutic targets, and future opportunities for public health interventions. The CURE Consortium will serve as a resource for ancillary studies.
This is a forecast for a limited competition Notice of Funding Opportunity (NOFO) that will invite application(s) from eligible organizations to apply. Application(s) will be peer-reviewed and only funded if meritorious.
Eligibility
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
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