LeverAging StraTegies to Maximize ImpLementation and Effectiveness for HIV (LAST MILE)
Forecasted Federal grant Posted
- Opportunity number
- RFA-AI-28-015
- Agency
-
National Institutes of Health
Department of Health and Human Services
- Applications expected due
- Award size
- Not on record
Opportunity facts
- Expected posting
- Assistance listings
- Funding instrument
- Cooperative Agreement
- Category
-
- Health
- Eligible applicants
-
- For Profit Organizations
- Special District Governments
- Higher Education Inst. (Public)
- Higher Education Inst. (Private)
- Tribal Governments (Federally Recognized)
- Non-501(c)(3) Nonprofits
- Tribal Organizations (Not Federally Recognized)
- County Governments
- 501(c)(3) Nonprofits
- Other
- Independent School Districts
- Small Businesses
- State Governments
- City/Township Governments
- Public or Indian Housing Auth.
- Points of contact
Opportunity details come from Grants.gov. Updated .
About this opportunity
The National Institute of Allergy and Infectious Diseases (NIAID) seeks applicants for the LeverAging StraTegies to Maximize ImpLementation and Effectiveness for HIV (LAST MILE) program, a cooperative agreement opportunity that funds effectiveness trials bridging clinical research to real-world HIV prevention and treatment implementation, with no application deadline specified in this forecast.
Eligible applicants include for-profit organizations, state and local governments, federally recognized tribal governments, nonprofit organizations (501(c)(3) and non-501(c)(3)), higher education institutions (public and private), small businesses, Indian housing authorities, independent school districts, eligible federal agencies, U.S. territories and possessions, faith-based and community-based organizations, regional organizations, and non-domestic entities.
The program targets combined efficacy-effectiveness trials, pragmatic trials, and hybrid effectiveness-implementation studies addressing HIV prevention and treatment across diverse populations and care settings, including management of associated coinfections and comorbidities in any age group. Research spans clinical, behavioral and social sciences, epidemiology, and implementation science domains. Work may be performed in any location consistent with the research focus.
Evaluation emphasizes scientific merit, technical adequacy of experimental design, investigator competency, facility adequacy, budget justification relative to proposed activities, and alignment with program objectives. NIAID applies standard NIH peer review processes: initial scientific review by an appropriate study section and subsequent national advisory council consideration based on priority scores and program balance.
The opportunity operates under CFDA 93.855 (Allergy and Infectious Diseases Research) and derives authority from Sections 301 and 405 of the Public Health Service Act and applicable federal regulations (42 CFR Part 52 and 2 CFR Part 200). This is a forecast; specific deadlines, award amounts, and number of awards will appear in the formal NOFO.
Forecast synopsis
The National Institute of Allergy and Infectious Diseases (NIAID) seeks to advance its mission through the LeverAging StraTegies to Maximize ImpLementation and Effectiveness for HIV (LAST MILE) program. This program will encourage collaborations to perform effectiveness trials that incorporate implementation in real-world settings. Examples include combined efficacy-effectiveness trials, pragmatic trials, and hybrid effectiveness-implementation studies. The intent is to bridge findings from traditional clinical trials to real-world implementation. The work will focus on populations across various points of care for prevention or treatment of HIV and its associated coinfections and comorbidities occurring in any age group. The goal of this program is to advance cross-cutting areas of HIV research, including clinical, behavioral and social sciences, epidemiology, and implementation science. This program aligns with the NIH mission to implement advances in HIV/AIDS research. Grant authorities that allow NIAID to forecast this opportunity are as follows: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.
Eligibility
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
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