Investigator Initiated Clinical Trials of Complementary and Integrative Interventions Delivered Remotely or via mHealth (R01 Clinical Trial Required)
Open Posted
- Opportunity number
- PAR-25-268
- Agency
-
National Institutes of Health
Department of Health and Human Services
- Applications due
- Award size
- Not on record
Opportunity facts
- Assistance listings
- Funding instrument
- Grant
- Category
-
- Health
- Eligible applicants
-
- Non-501(c)(3) Nonprofits
- Tribal Organizations (Not Federally Recognized)
- Independent School Districts
- Higher Education Inst. (Public)
- City/Township Governments
- Public or Indian Housing Auth.
- State Governments
- 501(c)(3) Nonprofits
- County Governments
- Tribal Governments (Federally Recognized)
- Higher Education Inst. (Private)
- Small Businesses
- Special District Governments
- For Profit Organizations
- Other
- Points of contact
-
- NIH OER Webmaster grantsinfo@nih.gov
- Full announcement
Opportunity details come from Grants.gov. Updated .
About this opportunity
The National Institutes of Health National Center for Complementary and Integrative Health seeks applicants for investigator-initiated fully remotely delivered and conducted clinical trials assessing the efficacy or effectiveness of complementary and integrative health interventions in NCCIH-designated areas of high research priority, with applications due November 17, 2026.
Eligible applicant categories include non-501(c)(3) nonprofits, tribal organizations (not federally recognized), independent school districts, public and private higher education institutions, city and township governments, public or Indian housing authorities, state governments, 501(c)(3) nonprofits, county governments, federally recognized tribal governments, small businesses, special district governments, for-profit organizations, Alaska Native and Native Hawaiian serving institutions, Asian American Native American Pacific Islander serving institutions, faith-based or community-based organizations, Hispanic-serving institutions, historically black colleges and universities, tribally controlled colleges and universities, and U.S. territories or possessions. Non-domestic (non-U.S.) entities and non-domestic components of U.S. organizations are not eligible; however, foreign components as defined in the NIH Grants Policy Statement are allowed.
Applications must propose a fully powered clinical trial with no in-person contact between research staff and study participants and may utilize mHealth tools or technologies. Applicants must provide justification for the remotely delivered approach and preliminary data on feasibility and safety of the approach, along with evidence that the intervention has promise of clinical benefit. A Plan for Enhancing Diverse Perspectives (PEDP) is required and will be assessed during scientific and technical peer review; applications lacking a PEDP will be considered incomplete and withdrawn. Applicants are encouraged to contact the appropriate NCCIH scientific or research contact prior to submission.
The opportunity operates under CFDA 93.213 (Research and Training in Complementary and Integrative Health) and requires an R01 Clinical Trial mechanism.
Synopsis
2 versions
Update #2 · Latest ·
This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated fully remotely delivered and conducted clinical trials to assess the efficacy or effectiveness of complementary and integrative health interventions in NCCIH- designated areas of high research priority. Applications submitted under this NOFO are expected to propose a remotely delivered and conducted fully powered clinical trial with no in-person contact between research staff and study participants and may utilize mHealth tools or technologies. Applicants must provide justification for the remotely delivered approach and provide preliminary data on the feasibility and safety of the approach, along with evidence that the intervention has promise of clinical benefit. Applicants are encouraged to contact the appropriate NCCIH Scientific/Research contact for the area of science for which they are planning to develop an application prior to submitting to this NOFO.
Update #1 ·
This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated fully remotely delivered and conducted clinical trials to assess the efficacy or effectiveness of complementary and integrative health interventions in NCCIH- designated areas of high research priority. Applications submitted under this NOFO are expected to propose a remotely delivered and conducted fully powered clinical trial with no in-person contact between research staff and study participants and may utilize mHealth tools or technologies. Applicants must provide justification for the remotely delivered approach and provide preliminary data on the feasibility and safety of the approach, along with evidence that the intervention has promise of clinical benefit. Applicants are encouraged to contact the appropriate NCCIH Scientific/Research contact for the area of science for which they are planning to develop an application prior to submitting to this NOFO. This NOFO requires a Plan for Enhancing Diverse Perspectives (PEDP), which will be assessed as part of the scientific and technical peer review evaluation. Applications that fail to include a PEDP will be considered incomplete and will be withdrawn. Applicants are strongly encouraged to read the NOFO instructions carefully and view the available PEDP guidance material.
Eligibility
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Files
| File | Type | Posted |
|---|---|---|
| PAR-25-268-Full-Announcement.html | HTML file | |
| PKG00288881.pdf |
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