Investigate Novel Therapeutic Interventions and Testing Strategies for Neurological Disorders Including to Treat, Modify and Prevent the Development of Epilepsy (U24 Clinical Trial Not Allowed)
Past Federal grant forecast Posted
- Opportunity number
- RFA-NS-26-002
- Agency
-
National Institutes of Health
Department of Health and Human Services
- Applications expected due
- Award size
- $3,500,000 to $4,000,000
Opportunity facts
- Expected posting
- Assistance listings
- Funding instrument
- Cooperative Agreement
- Category
-
- Health
- Eligible applicants
-
- Tribal Organizations (Not Federally Recognized)
- Higher Education Inst. (Public)
- Tribal Governments (Federally Recognized)
- State Governments
- 501(c)(3) Nonprofits
- Special District Governments
- Other
- Higher Education Inst. (Private)
- For Profit Organizations
- County Governments
- Small Businesses
- Public or Indian Housing Auth.
- City/Township Governments
- Independent School Districts
- Non-501(c)(3) Nonprofits
- Points of contact
-
- Brian Klein brian.klein@nih.gov (301) 496-0981
Opportunity details come from Grants.gov. Updated .
About this opportunity
The National Institute of Neurological Disorders and Stroke (NINDS) is forecasting a Notice of Funding Opportunity to solicit cooperative agreement applications investigating novel therapeutic interventions and testing strategies for neurological disorders, including approaches to treat, modify, and prevent epilepsy. This is a forecast; no hard application or letter-of-intent due date is specified in the source.
NINDS will fund research across diverse intervention modalities and testing strategies, with particular encouragement for investigators with expertise in preclinical therapy testing, model development, and human-focused testing approach validation. Applicants must emphasize novel therapeutic development and rigorous testing methodologies rather than clinical trials, which are explicitly not allowed under the U24 mechanism.
Eligible applicants include higher education institutions (public and private), state and local governments, tribal organizations (federally and non-federally recognized), 501(c)(3) and non-501(c)(3) nonprofits, small businesses, for-profit organizations, faith-based and community-based organizations, federal agencies, U.S. territories and possessions, regional organizations, and foreign institutions.
The opportunity falls under NINDS's Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853), which historically emphasizes project grants and cooperative agreements supporting basic and translational neuroscience research. Evaluation criteria assess scientific merit and significance, technical adequacy of experimental design, investigator competency, facility adequacy, budget necessity, and alignment with program objectives. Research applications requesting $500,000 or more in direct costs annually require prior NINDS approval.
No award ceiling, floor, or expected number of awards is specified in the forecast document.
Forecast synopsis
The National Institute of Neurological Disorders and Stroke (NINDS) intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications to investigate novel therapeutic interventions and testing strategies for neurological disorders including to treat, modify, and prevent epilepsy. This research should include various intervention modalities and testing strategies. Investigators should consider testing strategies for the development and validation of human-focused testing approaches. Investigators with expertise and insights into preclinical therapy testing and model development are encouraged to consider applying for this new NOFO.
Eligibility
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
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