Interdisciplinary Research to Understand the Complex Biology of Resilience to Alzheimer's and Related Dementias Disease Risk
Past Federal grant forecast Posted
- Opportunity number
- PAR-26-067
- Agency
-
National Institutes of Health
Department of Health and Human Services
- Applications expected due
- Award size
- Not on record
Opportunity facts
- Expected posting
- Assistance listings
-
- 93.866 Aging Research
- Funding instrument
- Cooperative Agreement
- Category
-
- Health
- Eligible applicants
-
- City/Township Governments
- County Governments
- Independent School Districts
- Special District Governments
- Tribal Governments (Federally Recognized)
- Non-501(c)(3) Nonprofits
- Higher Education Inst. (Public)
- Tribal Organizations (Not Federally Recognized)
- Public or Indian Housing Auth.
- For Profit Organizations
- 501(c)(3) Nonprofits
- Small Businesses
- Other
- State Governments
- Higher Education Inst. (Private)
- Points of contact
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- Suzana Petanceska petanceskas@nia.nih.gov (301) 496-9350
Opportunity details come from Grants.gov. Updated .
About this opportunity
The National Institute on Aging is forecasting a Notice of Funding Opportunity under the Aging Research program (CFDA 93.866) using cooperative agreement funding (U01 activity code) to support interdisciplinary research into molecular mechanisms of resilience to Alzheimer's disease and related dementias, with no application submission date set at this time.
Eligible applicants include higher education institutions (public and private), 501(c)(3) and non-501(c)(3) nonprofits, state and local governments, tribal governments (federally recognized and other), small businesses, for-profit organizations, faith-based and community-based organizations, regional organizations, foreign institutions, and other entity types listed in the opportunity announcement. The program explicitly invites potential applicants to develop meaningful collaborations during this forecasting phase; formal applications are not currently being solicited.
The NOFO targets data-driven, systems-based approaches—including artificial intelligence and machine learning methods—to discover molecular and cellular determinants of resilience across representative populations. Research should integrate epidemiologic, genomic, and mechanistic investigations and generate high-dimensional molecular data from brain and peripheral tissues, including longitudinal data, to enable dynamic modeling of resilience mechanisms and identify molecular predictors of resilience to AD/ADRD risk.
Award amounts, number of expected awards, period of performance, and cost-sharing requirements are not specified in the forecast announcement. NIH cooperative agreements under the Aging Research program typically support three- to five-year projects and undergo initial peer review followed by secondary review by the National Advisory Council on Aging. Standard NIH evaluation criteria assess scientific merit, experimental design, investigator competency, facility adequacy, budget justification, and alignment with program objectives.
Forecast synopsis
The National Institute on Aging (NIA) intends to publish a Notice of Funding Opportunity (NOFO) that builds upon its investment in data-driven approaches for the purpose of defining molecular mechanisms of resilience in the presence of various types of Alzheimer's disease (AD) and AD-related dementias (ADRD) risk. The goal of this NOFO is to build a robust program that integrates epidemiologic, genomic, and mechanistic research through the use of data driven, systems-based approaches (including the use of artificial intelligence and/or machine learning methods) to discover the molecular/cellular determinants of resilience to AD/ADRD risk across representative populations. The initiative will support the generation of high-dimensional molecular data from brain and peripheral tissues, including longitudinal data, to enable dynamic modeling of resilience mechanisms and to discover molecular predictors of resilience.
Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO intends to utilize the U01 activity code. Investigators with expertise and insights into this area of aging research are encouraged to begin to consider applying for this new NOFO.
Eligibility
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
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