Informatics, Coordination and Service Center for the Mutant Mouse Resource and Research Centers (U42 Clinical Trial Not Allowed)
Closed Posted
- Opportunity number
- RFA-OD-25-012
- Agency
-
National Institutes of Health
Department of Health and Human Services
- Applications due
- Award size
- Not on record
Opportunity facts
- Assistance listings
- Funding instrument
- Grant
- Category
-
- Health
- Eligible applicants
-
- 501(c)(3) Nonprofits
- Higher Education Inst. (Private)
- County Governments
- For Profit Organizations
- Small Businesses
- City/Township Governments
- Other
- Non-501(c)(3) Nonprofits
- State Governments
- Special District Governments
- Higher Education Inst. (Public)
- Points of contact
-
- Oleg Mirochnitchenko oripdcm@nih.gov
- Oleg Mirochnitchenko oripdcm@mail.nih.gov (301) 435-0744
Opportunity details come from Grants.gov. Updated .
About this opportunity
The National Institutes of Health (NIH) is seeking applications for the Informatics, Coordination and Service Center (ICSC) for the Mutant Mouse Resource and Research Centers (MMRRC) consortium through a U42 cooperative agreement. The ICSC will provide critical informatics and coordination services, including maintaining a comprehensive database of mouse strains, operating a public website portal, processing orders, facilitating strain donations, and coordinating consortium activities. Key objectives include enhancing scientific rigor, transparency, and experimental reproducibility in biomedical research, with a special emphasis on developing new approach methodologies (NAMs) that complement traditional animal-based research. Evaluation criteria will likely focus on scientific merit, experimental design, investigator competency, available resources, and alignment with program objectives. The NOFO is expected to be published in Spring 2025, with an application due date anticipated in Summer 2025.
The anticipated budget is up to $650,000 in direct costs per year for a four-year project period. The grant will support a centralized informatics and service center that will serve biomedical researchers across multiple disciplines, with the primary performance location being the selected institution's research facilities. Eligible applicants include higher education institutions, non-profit organizations, for-profit organizations, and state and local governments in the United States. The project is expected to begin in January 2026, with the ICSC responsible for coordinating activities across multiple mouse research repositories and developing innovative research resources.
Synopsis
The purpose of this Notice of Funding Opportunity (NOFO) is to provide continuing support for the Informatics, Coordination and Service Center (ICSC) unit of the Mutant Mouse Resource and Research Centers (MMRRC) consortium. The ICSC is expected to provide informatics and coordinating services to the MMRRC consortium and biomedical researchers. Important functions of the ICSC are improvement, development, and maintenance of the Consortium"s in-house data management systems in a format that may facilitate their integration with other animal and non-animal resource databases and community standards for information accessibility and interoperability. Additional services include maintenance and further development of a public website portal and Customer Service Center; operation of the order processing system; review and processing of applications from donating investigators; facilitation of interactions with biomedical investigators, informatics services, database activities, and the archive of MMRRC documents and files; coordination of requests to donate mouse strains to the MMRRCs and to order mouse strains from the MMRRCs; oversight of marketing efforts; and completion of monthly and yearly metrics reports. Moreover, the ICSC will host and actively participate in the monthly teleconference, annual consortium meeting, and compose reports and summaries from these forums as requested by MMRRC consortium members or NIH staff. Of special interest of the announcement is a requirement of the Center"s close coordination with efforts to develop new approach methodologies (NAMs) that complement traditional animal-based research. These include cell culture, organoids, computational models, and microphysiological systems. Proposed activities should include collection and analysis of the comparative information on the use of NAMs that enhance the predictive power of human disease models and support their integration with traditional models.
Files
| File | Type | Posted |
|---|---|---|
| RFA-OD-25-012-Revised-Full-Announcement.html | HTML file |
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