Immune Drivers of Autoimmune Disease

Forecasted Federal grant Posted

Opportunity number
RFA-AI-28-011
Agency
Applications expected due
Award size
Not on record

Opportunity facts

Expected posting
Assistance listings
Funding instrument
Cooperative Agreement
Category
  • Health
Eligible applicants
  • City/Township Governments
  • County Governments
  • Tribal Governments (Federally Recognized)
  • Tribal Organizations (Not Federally Recognized)
  • Other
  • Small Businesses
  • 501(c)(3) Nonprofits
  • Public or Indian Housing Auth.
  • Independent School Districts
  • Special District Governments
  • For Profit Organizations
  • Higher Education Inst. (Private)
  • State Governments
  • Non-501(c)(3) Nonprofits
  • Higher Education Inst. (Public)
Points of contact

Opportunity details come from Grants.gov. Updated .

About this opportunity

The National Institute of Allergy and Infectious Diseases (NIAID) is forecasting a cooperative agreement opportunity to support the Immune Drivers of Autoimmune Disease (IDAD) network, a complex sustained collaboration aimed at understanding the earliest steps and triggers leading to autoimmunity and flare in humans with the ultimate vision of preventing autoimmune disease. This is a forecast; a specific application due date has not been announced.

Eligible applicants include higher education institutions (public and private), nonprofit organizations (501(c)(3) and non-501(c)(3)), for-profit organizations, small businesses, state and local governments, Indian tribes and tribal organizations (federally and non-federally recognized), faith-based or community-based organizations, regional organizations, eligible federal agencies, U.S. territories or possessions, and non-domestic entities.

The IDAD network prioritizes discovering pre-clinical immune mechanisms, developing autoimmunity risk and staging prediction tools and biomarkers, building preclinical cohorts, leveraging remote recruitment and sampling, and artificial intelligence and big data analytics. The initiative will establish an Infrastructure Opportunity Fund (IOF) to enable collaborative research projects among network awardees, and an IDAD Network Coordinating Center (NCC) to administer the IOF and coordinate network activities including Steering Committee meetings, resource sharing, data harmonization, and sample sharing.

The cooperative agreement operates under the Allergy and Infectious Diseases Research program (CFDA 93.855) and is authorized under Sections 301 and 405 of the Public Health Service Act (42 USC 241 and 284) and 42 CFR Part 52 and 2 CFR Part 2. Award details including ceiling, floor, and expected number of awards have not been specified in the forecast.

Forecast synopsis

The National Institute of Allergy and Infectious Diseases (NIAID) seeks to advance its mission through the continued support of the Immune Drivers of Autoimmune Disease (IDAD) network. This network aims to understand the earliest steps and triggers leading to autoimmunity and flare in humans, with the vision of ultimately preventing autoimmune disease. Priorities include discovering pre-clinical immune mechanisms, developing autoimmunity risk and staging prediction tools and biomarkers, building preclinical cohorts, leveraging remote recruitment and sampling, and artificial intelligence (AI)/big data. This complex, sustained collaboration relies on shared infrastructure to identify common triggers, pathways, and prevention opportunities. An Infrastructure Opportunity Fund (IOF) will be included in the initiative to provide the network the opportunity to conduct collaborative research projects. An IDAD Network Coordinating Center (NCC) will be responsible for administering the IOF and supporting additional coordinating activities amongst IDAD awardees, including the organization of Steering Committee meetings, resource sharing, data harmonization, sample sharing, and administering the IOF. Grant authorities that allow NIAID to forecast this opportunity are as follows: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 2.

Eligibility

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

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