Health and Extreme Weather Solutions-Focused Research Hubs (U54 - Clinical Trial Optional)

Forecasted Federal grant Posted

Opportunity number
RFA-ES-28-002
Agency
Applications expected due
Award size
Up to $2,000,000

Opportunity facts

Expected posting
Assistance listings
Funding instrument
Cooperative Agreement
Category
  • Health
Eligible applicants
  • City/Township Governments
  • For Profit Organizations
  • Independent School Districts
  • Non-501(c)(3) Nonprofits
  • Higher Education Inst. (Private)
  • Tribal Organizations (Not Federally Recognized)
  • Other
  • State Governments
  • Tribal Governments (Federally Recognized)
  • 501(c)(3) Nonprofits
  • Higher Education Inst. (Public)
  • Small Businesses
  • Special District Governments
  • Public or Indian Housing Auth.
  • County Governments
Points of contact

Opportunity details come from Grants.gov. Updated .

About this opportunity

The National Institute of Environmental Health Sciences is forecasting a Notice of Funding Opportunity to solicit cooperative agreement applications for regional translational research hubs addressing health impacts of extreme weather and cumulative exposures, including but not limited to wildfire smoke, extreme heat, flooding, hurricanes, drought, and climate-related hazards affecting populations at heightened risk; no hard deadline is specified in this forecast.

Eligible applicants include city and township governments, for-profit organizations, independent school districts, non-501(c)(3) nonprofits, private and public higher education institutions, tribal organizations (federally and non-federally recognized), state governments, small businesses, special district governments, housing authorities, county governments, federal agencies, U.S. territories, faith-based and community-based organizations, and regional organizations.

Applications must be led by multidisciplinary teams including non-academic partners such as state and local public health departments, community-based organizations, tribal entities, health care systems, and emergency preparedness agencies. Consortia of multiple institutions are encouraged, particularly those demonstrating meaningful community engagement and balanced, mutually beneficial partnership structures. Research can span the translational continuum from fundamental to implementation research, with emphasis on problem-based, solutions-oriented approaches that clearly inform implementation, scalability, and measurable public health impact. Award recipients must collaborate with the HEW Research Coordination and Data Center(s) and participate in data harmonization efforts, shared metrics development, and cross-site dissemination activities.

The cooperative agreement uses the U54 activity code, which supports specialized centers functioning as regional resources for targeted research initiatives, including infrastructure development, pilot projects, and community partnerships. The award falls under CFDA 93.113 (Environmental Health).

Forecast synopsis

The National Institute of Environmental Health Sciences (NIEHS) intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications that propose translational research hubs with multiple highly integrated components focused on research, capacity building, and community/public health translation for regionally relevant topics related to the health impacts of extreme weather and cumulative exposures, including but not limited to wildfire smoke, extreme heat, flooding, hurricanes, drought, and other climate-related hazards affecting populations at heightened risk across the lifespan. Responsive applications will be led by a multidisciplinary team of investigators with non-academic partners, such as state and local public health departments, community-based organizations, Tribal entities, health care systems, and emergency preparedness agencies. Consortia of multiple institutions are encouraged, particularly those that demonstrate meaningful community engagement and balanced, mutually beneficial partnership structures. Research can be situated at different nodes on the translational research continuum, spanning from fundamental to implementation research with a focus on being problem-based and solutions oriented, and should clearly inform pathways to support implementation, scalability, and measurable public health impact. Award recipients will be expected to collaborate with the HEW Research Coordination and Data Center(s) and other members of the HEW Community of Practice, including participation in data harmonization efforts, shared metrics development, and cross-site dissemination activities. This NOFO will utilize the U54 activity code, that supports specialized centers that function as regional resources for targeted research initiatives, including support for infrastructure development, pilot projects, and partnerships with affected communities throughout the research lifecycle. The U54 is a cooperative agreement that anticipates substantial federal programmatic staff involvement to assist investigators in the achievement of project objectives, including coordination across funded hubs, strategic alignment with NIH priorities, and facilitation of cross-institute collaboration. Grant authorities that allow NIEHS to forecast this opportunity are as follows: 42 USC 285l (NIEHS specific); 42 USC sections 241 (NIH grant authorities).

Eligibility

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations

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