HEAL Initiative: Program to Reveal and Evaluate Cells-to-gene Information that Specify Intricacies, Origins and the Nature of (PRECISION) Human Pain Network

Past Federal grant forecast Posted

Opportunity number
RFA-NS-26-013
Agency
Applications expected due
Award size
Not on record

Opportunity facts

Expected posting
Funding instrument
Cooperative Agreement
Category
  • Health
Eligible applicants
  • For Profit Organizations
  • Other
  • Tribal Governments (Federally Recognized)
  • City/Township Governments
  • Special District Governments
  • 501(c)(3) Nonprofits
  • Public or Indian Housing Auth.
  • Non-501(c)(3) Nonprofits
  • State Governments
  • Small Businesses
  • Tribal Organizations (Not Federally Recognized)
  • Independent School Districts
  • Higher Education Inst. (Private)
  • Higher Education Inst. (Public)
  • County Governments

Opportunity details come from Grants.gov. Updated .

About this opportunity

The National Institute of Neurological Disorders and Stroke, in conjunction with other NIH Institutes and Centers as part of the congressionally mandated HEAL initiative, forecasts publication of a Notice of Funding Opportunity to solicit applications for comprehensive omics and physiology dataset generation using primary human tissue across the pain neuraxis; applications are not being solicited at this time, and a specific deadline has not been announced.

This cooperative agreement mechanism seeks large-scale, high-throughput data generation and analysis of human genes, epigenome, transcriptome, proteome, metabolome, and phenotyping of neuronal and non-neuronal cells at single-cell and tissue levels. The work will expand generation and dissemination of comprehensive datasets using primary pain-associated human tissues, incorporate cutting-edge technologies, enhance coverage across multiple pain conditions, and extend integration and harmonization of multimodal outputs. Awarded centers will work collaboratively as a network to develop best practices, optimize protocols, replicate and cross-validate research findings, and collectively build an integrated knowledgebase with digital resources for the pain research and therapeutics development communities. NIH program staff involvement is expected to coordinate alignment with the broader HEAL Data Sharing Ecosystem and account for evolving priorities.

Eligible applicants include for-profit organizations, nonprofits (501(c)(3) and non-501(c)(3)), tribal governments and organizations, state and local governments, higher education institutions (public and private), faith-based or community-based organizations, regional organizations, eligible federal agencies including NIH Intramural Program, U.S. territories, and non-domestic entities. The mechanism is milestone-driven. The forecast is issued to allow potential applicants sufficient time to develop meaningful multidisciplinary collaborations and responsive projects. The opportunity falls under CFDA 93.853 (Extramural Research Programs in the Neurosciences and Neurological Disorders).

Forecast synopsis

The National Institute of Neurological Disorders and Stroke, in conjunction with other NIH Institutes and Centers (ICs) as a part of the congressionally mandated NIH Helping to End Addiction Long Term (HEAL) initiative intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for comprehensive 'omics and physiology dataset generation using primary human tissue across the pain neuraxis. Applications should focus on large-scale, high-throughput data generation and analysis of human genes, epigenome, transcriptome, proteome, metabolome, and phenotyping of neuronal and non-neuronal cells at the single-cell and tissue levels. This NOFO is intended as a continuation of the NIH HEAL Initiative's Program to Reveal and Evaluate Cells-to-gene Information that Specify Intricacies, Origins and the Nature of (PRECISION) Human Pain Network. The goal of this research will be to expand the generation and dissemination of comprehensive datasets using primary pain-associated human tissues, incorporate cutting-edge technologies, enhance coverage across multiple pain conditions, and extend integration and harmonization of multimodal outputs. This NOFO will utilize a milestone-driven, cooperative agreement mechanism, in which awarded centers will work collaboratively as a network to develop best practices, optimize protocols, replicate and cross-validate research findings, and collectively build an integrated knowledgebase, with digital resources for the entire pain research and therapeutics development communities. NIH program staff involvement is expected to coordinate alignment with the broader HEAL Data Sharing Ecosystem and account for evolving priorities to ensure program objectives are achieved.

Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful multidisciplinary collaborations and responsive projects. Investigators with expertise and insights into comprehensive 'omics and physiology dataset generation in primary human tissue are encouraged to consider applying for this NOFO. In addition, applications from collaborating, multidisciplinary teams of neurobiologists, pain biologists, human pain scientists and/or physicians, surgeons, and scientists with expertise in statistics, physics, engineering, and bioinformatics should consider applying to this funding opportunity.

Eligibility

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government, including the NIH Intramural Program;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

On GovTribe

Work this opportunity

  • Track it in your pipeline
  • Find teaming partners
  • Similar grant opportunities
  • Ask GovTribe AI about this opportunity