Expanding the Therapeutic Pipeline for Treating and Preventing Alzheimer's Disease and Related Dementias: Preclinical Validation and Drug Discovery for Novel Candidate Targets (U01 Clinical Trial Not Allowed)
Past Federal grant forecast Posted
- Opportunity number
- PAR-26-132
- Agency
-
National Institutes of Health
Department of Health and Human Services
- Applications expected due
- Award size
- Not on record
Opportunity facts
- Expected posting
- Assistance listings
-
- 93.866 Aging Research
- Funding instrument
- Cooperative Agreement
- Category
-
- Health
- Eligible applicants
-
- Other
- Small Businesses
- Higher Education Inst. (Public)
- Higher Education Inst. (Private)
- Non-501(c)(3) Nonprofits
- Special District Governments
- For Profit Organizations
- Tribal Governments (Federally Recognized)
- County Governments
- 501(c)(3) Nonprofits
- Tribal Organizations (Not Federally Recognized)
- City/Township Governments
- Public or Indian Housing Auth.
- State Governments
- Independent School Districts
- Points of contact
Opportunity details come from Grants.gov. Updated .
About this opportunity
The National Institute on Aging is forecasting a Notice of Funding Opportunity using the U01 cooperative agreement activity code to solicit applications for preclinical validation and early-stage drug discovery targeting novel Alzheimer's disease and related dementias candidates; applications are not currently being solicited, but notice is provided to allow potential applicants time to develop collaborations.
Eligible applicants include higher education institutions (public and private), 501(c)(3) and non-501(c)(3) nonprofits, small businesses, for-profit organizations, tribal governments (federally recognized and not federally recognized), state and local governments, public or Indian housing authorities, independent school districts, faith-based and community-based organizations, U.S. territories or possessions, regional organizations, eligible federal agencies, and non-domestic entities.
The NOFO will support rigorous preclinical research on small molecules, biologics, and emerging therapeutic modalities for AD/ADRD drug target validation and early-stage drug discovery. The funding instrument is a cooperative agreement, indicating anticipated substantial federal involvement in project direction and management.
The program operates under Assistance Listing 93.866 (Aging Research). The National Institute on Aging's broader portfolio demonstrates recent award activity concentrated in Project Grants, with cooperative agreements representing approximately 2 percent of historical awards. Recent individual awards under 93.866 have ranged from under $50,000 to multi-million dollars. Standard review timelines run six to nine months from application to funding decision. Awards typically carry project periods not exceeding five years.
Interested investigators with expertise in AD/ADRD pathology and drug discovery are encouraged to begin developing responsive projects and meaningful collaborations in advance of formal solicitation.
Forecast synopsis
The National Institute on Aging (NIA) intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for research on Alzheimer's disease (AD) and AD-related dementias (ADRD) drug target validation and early-stage drug discovery against novel targets. This NOFO will utilize the U01 activity code. The NOFO will support rigorous preclinical AD/ADRD drug target validation and early-stage drug discovery of small molecules, biologic, and emerging therapeutic modalities. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. Investigators with expertise and insights into AD/ADRD and drug discovery are encouraged to begin to consider applying for this new NOFO.
Eligibility
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
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