Epidemiology of Lupus: Longitudinal Studies in Population-Based Cohorts

This NOFO is intended to support research on lupus through a 2-component cooperative agreement: Component A (Longitudinal Studies in Population-based Cohorts of Adults with Lupus: 3 Year Followup): This is a longitudinal followup study designed to support an established, US-based, population-based cohort of adults age 18 and older with diagnosed lupus (systemic lupus erythematosus {SLE} and skin lupus) that includes followup data collected at least once since 2015. The intent of this study is to conduct data collection, building upon the cohort and initial followup activities. This data collection should include four content areas: The natural history (e.g., severity, morbidity, mortality, disability, comorbidity, work interference, etc.) of cohort members, and Treatment (e.g., medications, therapy, self-management, etc.) of lupus including the treatment of chronic pain and opioid use, and Health care access and gaps that adults with lupus experience, and Disparities (e.g., age, race/ethnicity, sex) and other factors associated with lupus outcomes. Component B: (A Pediatric Lupus Registry with Longitudinal Follow up): This is a project that will support an existing US-based registry of children age 0-17 years with diagnosed lupus (SLE and skin lupus). The intent of this study is to gather baseline data for children age 0-17 years and follow up data for this cohort for three additional years. The baseline and follow up data should include these 4 content areas: The natural history (e.g., severity, morbidity, mortality, disability, comorbidity, work interference, etc.) of cohort members, and Treatment (e.g., medications, therapy, self-management, etc.) of lupus including the treatment of chronic pain and opioid use, and Health care access and gaps that children with lupus experience, and Disparities (e.g., age, race/ethnicity, sex) and other factors associated with lupus outcomes.

This NOFO is intended to support research on lupus through a 2-component cooperative agreement:Component A (Longitudinal Studies in Population-based Cohorts of Adults with Lupus: 3 Year Followup):This is a longitudinal followup study designed to support an established, US-based, population-based cohort of adults age 18 and older with diagnosed lupus (systemic lupus erythematosus {SLE} and skin lupus) that includes followup data collected at least once since 2015. The intent of this study is to conduct data collection, building upon the cohort and initial followup activities. This data collection should include four content areas:The natural history (e.g., severity, morbidity, mortality, disability, comorbidity, work interference, etc.) of cohort members, andTreatment (e.g., medications, therapy, self-management, etc.) of lupus including the treatment of chronic pain and opioid use, andHealth care access and gaps that adults with lupus experience, andDisparities (e.g., age, race/ethnicity, sex) and other factors associated with lupus outcomes.Component B: (A Pediatric Lupus Registry with Longitudinal Follow up):This is a project that will support an existing US-based registry of children age 0-17 years with diagnosed lupus (SLE and skin lupus). The intent of this study is to gather baseline data for children age 0-17 years and follow up data for this cohort for three additional years. The baseline and follow up data should include these 4 content areas:The natural history (e.g., severity, morbidity, mortality, disability, comorbidity, work interference, etc.) of cohort members, andTreatment (e.g., medications, therapy, self-management, etc.) of lupus including the treatment of chronic pain and opioid use, andHealth care access and gaps that children with lupus experience, andDisparities (e.g., age, race/ethnicity, sex) and other factors associated with lupus outcomes.

This NOFO is intended to support research on lupus through a 2-component cooperative agreement: Component A (Longitudinal Studies in Population-based Cohorts of Adults with Lupus: 3 Year Followup): This is a longitudinal followup study designed to support an established, US-based, population-based cohort of adults age 18 and older with diagnosed lupus (systemic lupus erythematosus {SLE} and skin lupus) that includes followup data collected at least once since 2015. The intent of this study is to conduct data collection, building upon the cohort and initial followup activities. This data collection should include four content areas: The natural history (e.g., severity, morbidity, mortality, disability, comorbidity, work interference, etc.) of cohort members, and Treatment (e.g., medications, therapy, self-management, etc.) of lupus including the treatment of chronic pain and opioid use, and Health care access and gaps that adults with lupus experience, and Disparities (e.g., age, race/ethnicity, sex) and other factors associated with lupus outcomes. Component B: (A Pediatric Lupus Registry with Longitudinal Follow up): This is a project that will support an existing US-based registry of children age 0-17 years with diagnosed lupus (SLE and skin lupus). The intent of this study is to gather baseline data for children age 0-17 years and follow up data for this cohort for three additional years. The baseline and follow up data should include these 4 content areas: The natural history (e.g., severity, morbidity, mortality, disability, comorbidity, work interference, etc.) of cohort members, and Treatment (e.g., medications, therapy, self-management, etc.) of lupus including the treatment of chronic pain and opioid use, and Health care access and gaps that children with lupus experience, and Disparities (e.g., age, race/ethnicity, sex) and other factors associated with lupus outcomes.