Engineering Biological and Biomedical Systems (EBBS)
Posted
- Opportunity number
- PD-26-369Y
- Agency
-
National Science Foundation
- Applications due
- Not on record
- Award size
- Not on record
Opportunity facts
- Assistance listings
-
- 47.041 Engineering
- Funding instrument
- Grant
- Category
-
- Science and Technology and other Research and Development
- Eligible applicants
-
- Unrestricted
- Points of contact
- Full announcement
Opportunity details come from Grants.gov. Updated .
About this opportunity
The National Science Foundation is soliciting applications for the Engineering Biological and Biomedical Systems (EBBS) program, which supports fundamental engineering research that expands understanding of biological and physiological systems to improve human health; no application due date is specified in the posted materials.
Applicants are unrestricted. The program funds research combining mechanistic insights with experimental and computational techniques to develop platforms, devices, organisms, tissues, and processes that control biological functions. Priority research areas include mechanisms driving microbial and cellular behavior; therapeutic cells and tissues; engineering principles for biological system responses and bioreactors; novel biosensing platforms; optical imaging and modulation strategies; biological systems designed to sense and respond to novel stimuli; tissue changes and injury insights; systems imitating or restoring tissue and organ functions; rehabilitation engineering through new theories and approaches; fundamental engineering research driven by disability needs; and biomanufacturing advancement.
EBBS research must enable improved biological processes, create novel biomedical technologies, or achieve new understanding of physiological or pathological processes. The program excludes proposals with primary goals of drug design, drug delivery, or animal disease model development. Existing models are acceptable for experimental testing and validation. Projects focused on therapy testing and validation, and clinical trials, receive no support.
The program operates under NSF's Directorate for Engineering (CFDA 47.041). Applicants must register with NSF, obtain Unique Entity Identifiers through the System for Award Management, and establish NSF accounts. Applications are submitted through Grants.gov and completed in Research.gov. Senior key personnel salary compensation is limited to two months per year unless specifically approved. Data management and sharing plans are limited to two pages maximum.
Synopsis
2 versions
Update #2 · Latest ·
The Engineering Biological and Biomedical Systems (EBBS) program expands our understanding of biological and physiological systems, and it helps improve human health. For U.S. leadership in biotechnology, the engineering of biology is required at every scale. Engineering is needed for sensing biomarkers to making proteins to restoring functions of the body. In EBBS, fundamental mechanistic insights are combined with experimental and computational techniques. This approach helps develop platforms, devices, organisms, tissues, and processes that bring new understanding and control of biological functions. EBBS supports studies of mechanisms that drive the behavior of microbial populations and cells, and of therapeutic cells and tissues. This includes discovering the underlying engineering principles that are needed to capture the responses of biological systems and bioreactors. It also includes the creation of novel biosensing platforms and new optical imaging and modulation strategies. Research that enables the design of biological systems to sense and respond to novel stimuli is welcome. Similarly, projects leading to insight into tissue changes or injury, and to systems that imitate or restore the functions of tissues or organs are encouraged. Projects that advance rehabilitation engineering through new theories and approaches are supported by the EBBS program. Fundamental engineering research driven by the needs of persons with disabilities is encouraged. The EBBS program expands what is possible in biomanufacturing; research may advance biotechnology and/or health. EBBS research must enable improved biological processes, create novel biomedical technologies, or achieve new understanding of physiological or pathological processes. EBBS does not support proposals with a main goal of drug design, drug delivery, or the development of animal models of disease. Using existing models for experimental testing and validation is acceptable. Projects that focus on testing and validating therapies are not supported. Clinical trials are not supported. Limited studies involving human volunteers may be supported if appropriate to the project objectives. Projects focused on commercialization are more appropriate for the NSF Directorate for Technology, Innovation, and Partnerships (TIP). Partnerships: To speed discovery and innovation, NSF partners with federal agencies, industry, international groups, and others. Current opportunities are at NSF ENG Partnerships.
Update #1 ·
TheEngineering Biological and Biomedical Systems(EBBS)program expandsour understanding of biological and physiological systems,andithelpsimprove humanhealth.ForU.S.leadershipin biotechnology,theengineeringofbiologyisrequiredat every scale.Engineering is needed forsensingbiomarkerstomakingproteinsto restoring functions of the body.InEBBS,fundamentalmechanistic insightsarecombinedwith experimental and computational techniques.Thisapproachhelpsdevelopplatforms, devices, organisms, tissues,andprocesses thatbringnewunderstanding and control of biological functions.
EBBSsupportsstudies of mechanismsthatdrivethe behavior of microbial populations and cells,and of therapeutic cells and tissues.This includes discovering theunderlying engineering principlesthat are needed tocapturethe responses of biological systems and bioreactors.It alsoincludesthecreationofnovelbiosensing platformsandnew optical imaging and modulation strategies.Research that enables the design of biological systems to sense and respond to novel stimuli is welcome. Similarly, projects leading to insight intotissuechangesor injury,andtosystems thatimitateor restorethefunctionsoftissuesororgans areencouraged.
Projects thatadvancerehabilitation engineeringthrough new theories and approaches are supported by the EBBS program. Fundamental engineering research driven by theneeds of persons with disabilitiesis encouraged.
The EBBS programexpandswhat is possible inbiomanufacturing;researchmayadvancebiotechnology and/orhealth.EBBSresearchmustenableimprovedbiological processes,createnovelbiomedical technologies, orachievenewunderstanding of physiological or pathological processes.
EBBSdoesnot support proposalswithamaingoal ofdrug design,drugdelivery, or the development of animal models of disease.Usingexisting models for experimental testing and validation is acceptable. Projectsthatfocus ontesting andvalidatingtherapiesare not supported.Clinical trials are not supported.Limitedstudies involving human volunteers may be supported ifappropriate tothe projectobjectives. Projects focused on commercialization are moreappropriate fortheNSFDirectorate for Technology, Innovation, and Partnerships (TIP).
Partnerships:Tospeeddiscovery and innovation, NSF partners with federal agencies, industry, internationalgroups, and others. Current opportunities are atNSF ENG Partnerships.
Files
| File | Type | Posted |
|---|---|---|
| PKG00292501.pdf |
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