Collaborative Awards to Support Microphysiological System Pilot Studies in Type 2 Diabetes Research (R21, Clinical Trial Not Allowed)
Past Federal grant forecast Posted
- Opportunity number
- RFA-DK-27-102
- Agency
-
National Institutes of Health
Department of Health and Human Services
- Applications expected due
- Award size
- Not on record
Opportunity facts
- Expected posting
- Assistance listings
- Funding instrument
- Grant
- Category
-
- Health
- Eligible applicants
-
- Public or Indian Housing Auth.
- Higher Education Inst. (Private)
- Other
- Special District Governments
- City/Township Governments
- Non-501(c)(3) Nonprofits
- For Profit Organizations
- Independent School Districts
- Higher Education Inst. (Public)
- 501(c)(3) Nonprofits
- Tribal Governments (Federally Recognized)
- County Governments
- State Governments
- Tribal Organizations (Not Federally Recognized)
- Small Businesses
- Points of contact
-
- Albert J. Hwa, PhD albert.hwa@nih.gov (301) 451-1525
Opportunity details come from Grants.gov. Updated .
About this opportunity
The National Institute of Diabetes and Digestive and Kidney Diseases is forecasting a Notice of Funding Opportunity to solicit applications for research on microphysiological systems modeling type 2 diabetes, with no application due date set as this is a pre-announcement; applications are not currently being solicited.
Eligible applicants include higher education institutions (public and private), 501(c)(3) nonprofits, for-profit organizations, small businesses, state and local governments, tribal governments (federally recognized and other), other nonprofits, housing authorities, school districts, and other entities. Foreign institutions, faith-based and community-based organizations, and eligible federal agencies may also apply.
The initiative supports small pilot studies to conceptualize type 2 diabetes biology for microphysiological system modeling, feasibility studies, and preliminary data generation. The agency will encourage collaborative investigations combining expertise in bioengineering, type 2 diabetes biology, and human metabolism. Applications must use the R21 mechanism and cannot include clinical trials.
Award ceiling, floor, expected number of awards, period of performance, place of performance, cost share requirements, and evaluation criteria are not specified in the forecast notice.
This opportunity falls under CFDA 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research). The forecast is provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects prior to the formal NOFO release.
Forecast synopsis
The National Institute of Diabetes and Digestive and Kidney Diseases intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for research on microphysiological systems (MPSs) to model type 2 diabetes. Advances in biomaterials, microfluidics, and tissue engineering have resulted in MPSs that allow for greater control of three-dimensional cell cultures containing multiple cell types and constituting more physiological tissue organization. The utility of these systems lends themselves to powerful in vitro modeling of metabolic tissue crosstalk, study of basic mechanisms of human type 2 diabetes, and the testing of prevention and treatment strategies. MPSs are especially useful for investigating the heterogeneity of human T2D biology and clinical responses. The current initiative will support small pilot studies to conceptualize aspects of T2D biology for modeling with MPSs, to support feasibility studies, and to generate preliminary data. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. Collaborative investigations combining expertise in bioengineering, type 2 diabetes biology, and human metabolism will be encouraged and these investigators should begin considering applying for this application.
Eligibility
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
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