The Civil Infrastructure Systems (CIS) program, administered by the National Science Foundation (NSF), supports fundamental and innovative research in the design, operation, and management of civil infrastructure. The program focuses on civil infrastructure as an interconnected system, with a particular interest in research that addresses novel system and service design, system integration, big data analytics, and socio-technological-infrastructure connections. The program encourages potentially disruptive ideas that will open new frontiers and significantly broaden and transform relevant research communities. Applicants should have expertise in diverse theoretical, scientific, mathematical, or computational contributions from a broad set of disciplines. The CIS program typically awards grants ranging from $250,000 to $650,000, with project periods spanning 3-5 years. The awards predominantly support project grants focused on developing advanced technologies, exploring scientific phenomena, and creating innovative solutions to complex engineering challenges. Eligible applicants include academic institutions, research organizations, and other eligible entities across the United States.