Biology of Bladder Cancer (R01 Clinical Trial Optional)

Closed Posted

Opportunity number
PAR-25-129
Agency
Applications due
Award size
Not on record

Opportunity facts

Funding instrument
Grant
Categories
  • Education
  • Health
Eligible applicants
  • Non-501(c)(3) Nonprofits
  • City/Township Governments
  • State Governments
  • Tribal Organizations (Not Federally Recognized)
  • Tribal Governments (Federally Recognized)
  • Independent School Districts
  • County Governments
  • For Profit Organizations
  • 501(c)(3) Nonprofits
  • Special District Governments
  • Small Businesses
  • Public or Indian Housing Auth.
  • Higher Education Inst. (Public)
  • Higher Education Inst. (Private)
  • Other
Full announcement

Opportunity details come from Grants.gov. Updated .

About this opportunity

The Department of Health and Human Services National Institutes of Health is soliciting applications for the "Biology of Bladder Cancer (R01 Clinical Trial Optional)" federal grant opportunity. The purpose of this funding is to support research investigating the biology and underlying mechanisms of bladder cancer, a significant health problem. Eligible applicants include a range of organizations such as state and local governments, higher education institutions, nonprofits, and small businesses. The NIH encourages applications that involve multidisciplinary teams and use clinical specimens or investigate both normal and cancer processes related to the bladder. The deadline for submitting proposals is September 7, 2025.

Recent federal grant awards under the related Cancer Cause and Prevention Research (CFDA 93.393) and Cancer Biology Research (CFDA 93.396) programs have typically ranged from $200,000 to over $2 million per year, with project periods of 2-5 years. The research is expected to be conducted at the recipient institutions' facilities across the United States.

Synopsis

Through this Notice of Funding Opportunity (NOFO) solicits applications investigating the biology and underlying mechanisms of bladder cancer. Bladder cancer is a significant health problem both in the United States and globally. Because of the high incidence and frequent tumor recurrence, bladder cancer exacts an outsized medical burden. While recent progress has been made in the molecular profiling of bladder cancers and identification of mutated genes, relatively little is known regarding the molecular mechanisms driving initiation, progression, and malignancy of bladder cancer. Furthermore, our understanding of biological processes of the normal bladder at the molecular, cell and organ levels is limited. Fundamental knowledge of how molecular and cellular functions of the bladder are altered in cancer will aid our understanding of bladder cancer biology and interventions. Applications that involve multidisciplinary teams and use clinical specimens or investigate both normal and cancer processes are encouraged.

Files

File Type Posted
PAR-25-129-Full-Announcement.html HTML file

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