NIAID DMID Topic 131 (Phase II) "Development of Bacteriophage for Treatment of Mycobacterial Infections"
Past New Requirement Updated
- Agency
-
National Institutes of Health
Department of Health and Human Services
- Solicitation expected
- Estimated value
- $1,500,000 to $3,000,000
- Set-aside
- Total Small Business
Forecast facts
- Anticipated award
- NAICS code
- 541715 Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
- Points of contact
Forecast details come from HHS's procurement forecast. Agencies' dates and values are estimates.
About this forecast
The National Institutes of Health plans to release a solicitation on September 1, 2026 for Phase II preclinical research and development of therapeutic bacteriophage products targeting mycobacteria, with special emphasis on Non-Tuberculous Mycobacterial (NTM) infections, including antibiotic-resistant mycobacterial infections, under NIAID DMID Topic 131. The effort continues a Phase I contract that ended in September 2025 and includes Phase I activities within a milestone-driven Phase II period, as described in the attached Statement of Work. This Total Small Business set-aside falls under NAICS 541715, with an estimated award date of October 1, 2026, and both estimated dates precede the November 14, 2026 posting date.
The estimated award value range is $1.5 million to $3.0 million. Callie Prassinos, Contracting Officer at NIH (callie.prassinos@nih.gov, +1 240-669-5155), and James Boyce, Department of HHS (jim.boyce@nih.gov), are the listed points of contact.
Forecast text
The goal for Research Topic 131 is to provide support for preclinical research and development of
therapeutic phage products that target mycobacteria. Within this scope, special emphasis is placed on preclinical development of Non-Tuberculous Mycobacterial (NTM) infections; and including antibiotic-resistant mycobacterial infections. This is a continuation of a Phase I contract that ended in September 2025. If not continued in a planned milestone driven Phase II period, the investment in discoveries made during the Phase I period could languish or be lost. Phase II activities are described in the attached Statement of work and include continuation of Phase I activities.
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