TECHNOLOGY LICENSING OPPORTUNITY: 3-HP Upgrading Platform
Closed Special Notice Posted
- Solicitation number
- S-193777
- Agency
-
Department of Energy
- Responses due
- Set-aside
- No set-aside
Opportunity facts
- NAICS code
- 325199 All Other Basic Organic Chemical Manufacturing
- PSC
- 6810 Chemicals
- Place of performance
- Los Alamos, New Mexico 87545, United States
- Points of contact
-
- Satya Srinivasan licensing@lanl.gov
Notice details come from SAM.gov. Updated .
About this opportunity
The Department of Energy has released a Special Notice regarding a technology licensing opportunity for the 3-HP Upgrading Platform, a chemical process developed by Los Alamos National Laboratory. This technology enables the conversion of 3-hydroxypropionic acid (3-HP), a renewably produced compound, into methyl methacrylate (MMA) through an integrated reactive extraction approach. The opportunity was posted on April 24, 2026, with a deadline of May 11, 2026. The notice is classified under All Other Basic Organic Chemical Manufacturing (NAICS 325199) and the Chemicals category (PSC 6810). This licensing opportunity is open without any set-aside restrictions, making it available to all eligible commercial entities.
The primary objective of this Special Notice is to attract commercial licensees who can develop and commercialize the 3-HP Upgrading Platform for the production of MMA, a high-demand chemical used in plastics, coatings, adhesives, and medical materials. The technology offers licensees a differentiated, bio-based production route that reduces dependency on petroleum-derived feedstocks while potentially lowering production costs by eliminating costly purification steps and improving overall efficiency. Interested contractors should note the May 11, 2026 deadline for responding to this opportunity. While specific eligibility criteria are not detailed in the provided excerpt, the notice indicates that manufacturers seeking sustainable alternatives in the chemical production sector are the target audience. The platform presents broader applications beyond MMA production, as it can be extended to other bio-based molecules, positioning licensees to transform biomass-derived feedstocks into various industrial chemical intermediates.
Notice text
This technology from Los Alamos National Laboratory, 3-HP Upgrading Platform, provides a novel, bio-based pathway to produce methyl methacrylate (MMA) by converting renewably producible 3-hydroxypropionic acid (3-HP) into a constituent substrate for normally petroleum-derived MMA. By operating directly on fermentation-derived 3-HP, the process reduces the need for costly purification steps and improves overall production efficiency. It also introduces a novel chemical intermediate formed during the reaction, offering additional differentiation. For manufacturers, this approach enables a more sustainable and potentially lower-cost route to a high-demand chemical used in plastics, coatings, adhesives and medical materials—without requiring changes to existing products or end-use applications.
Overview:
This invention is a chemical process for upgrading 3-hydroxypropionic acid (3-HP) into methyl methacrylate (MMA) using an integrated reactive extraction approach. In this system, 3-HP produced through fermentation is directly converted within a solvent phase, where extraction and chemical transformation occur simultaneously. This design improves reaction selectivity and enables more efficient handling of aqueous fermentation streams compared to conventional multi-step methods. The process includes multiple novel reaction pathways—such as ester- and lactone-based routes—and generates a distinct intermediate during conversion. In addition to MMA production, the approach can be extended to other bio-based molecules, providing a broader platform for transforming biomass-derived feedstocks into industrial chemical intermediates.
The Opportunity:
The 3-HP Upgrading Platform presents licensees with an opportunity to enter or expand into the MMA market using a differentiated, bio-based production route that aligns with growing demand for sustainable materials. By enabling the conversion of renewably sourced 3-HP into a constituent substrate for normally petroleum-derived MMA, companies can reduce reliance on fossil feedstocks while maintaining compatibility with existing PMMA applications and supply chains. The process is particularly attractive for producers seeking to integrate upstream fermentation capabilities or diversify raw material inputs, offering a pathway to improve cost efficiency and supply resilience. As end markets increasingly prioritize lower-carbon and bio-based content—across automotive, electronics, construction and medical sectors—this technology positions licensees to capture value through sustainable product offerings without requiring changes to downstream manufacturing or product performance.
Key Advantages:
- Bio-based production route reducing reliance on petroleum feedstocks
- Drop-in compatibility with existing MMA/PMMA applications and supply chains
- Direct use of fermentation streams, minimizing purification requirements
- Improved process efficiency through integrated reaction and extraction
- Novel conversion pathway from 3-HP to MMA, including a unique intermediate
- Alignment with sustainability goals and growing demand for greener materials
Market Applications:
- Automotive (glazing, coatings, lightweight components)
- Electronics & Displays (screens, optical materials, housings)
- Construction & Infrastructure (panels, sealants, protective surfaces)
- Medical & Healthcare (devices, implants, coatings)
- Adhesives & Coatings (industrial coatings, finishes, bonding materials)
- Consumer & Industrial Plastics (transparent plastics, durable goods, 3D printing materials)
Development Status: TRL 3
US Patent pending
LA-UR-26-23337
LANL Tech Partnerships: Unlock the Innovative Potential
Los Alamos National Laboratory offers a wide range of cutting-edge technologies and capabilities that may provide your company with a competitive edge in the market and unlock the innovative potential that can enhance, refine, and revolutionize your products.
LANL’s licensing program focuses on moving inventions developed by our researchers to commercial innovations. Patented and patent pending inventions and copyrighted software are available to existing and start-up companies through exclusive and non-exclusive licensing agreements. For specific discussions, please contact licensing@lanl.gov.
Note: This is not a call for external services for the development of this technology.
https://www.lanl.gov/engage/collaboration/feynman-center/partner-with-us/licensing-technology
m.lanl.gov/tech-search
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