Synthesis of Therapeutic Agents for Treatment of Infectious Diseases

Introduction
The National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), of the Department of Health and Human Services (DHHS) supports research related to the basic understanding of microbiology and immunology leading to the development of vaccines, therapeutics, and medical diagnostics for the prevention, treatment, and diagnosis of infectious and immune-mediated diseases. The NIAID, Division of AIDS has a requirement for the synthesis of therapeutics directed against HIV and other infectious diseases as well as agents to serve and anti-HIV topical microbicides.

Description
This solicitation provides the resources for the synthesis of microbicides and compounds for the treatment of HIV, and other infectious diseases of relevance to the research agenda of NIAID. The contract will synthesize chemicals, in compliance with FDA's current Good Manufacturing Practice (cGMP) regulations if necessary, in quantities needed for testing in either in vitro screens, animals, or early Phase I clinical studies.

This is a 100% SMALL BUSINESS SET-ASIDE, NAICS 541712, with a size standard of 500 employees. The National Institute of Allergy and Infectious Diseases (NIAID) anticipates that one cost reimbursement, term (level of effort) type contract will be awarded for a one year base period of performance beginning on or about February 13, 2015. Options will be included to extend the term of the contract for an additional six years for a maximum period of performance of 7 years. The requirement will be for the delivery of 6.14 full time equivalents (FTEs) per year for the Base Period (Year 1) and each option period (Years 2 through 7).

Any responsible offeror may submit a proposal which will be considered by the Agency. This RFP will be available electronically on/about March 6, 2014, and may be accessed through FedBizOpps http://www.fedbizopps.gov/. This notice does not commit the Government to award a contract. No collect calls will be accepted. No facsimile transmissions will be accepted.

For this solicitation, the NIAID requires proposals to be submitted via two methods: (1)
Disc (CD or DVD) and (2) Online via the NIAID electronic Contract Proposal Submission (eCPS) website. The content of the disc and online proposals must be identical. Submission of proposals by facsimile or e-mail is not acceptable.

For directions on using eCPS, go to the website https://ecps.niaid.nih.gov and then click on "How to Submit."

Introduction
The National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), of the Department of Health and Human Services (DHHS) supports research related to the basic understanding of microbiology and immunology leading to the development of vaccines, therapeutics, and medical diagnostics for the prevention, treatment, and diagnosis of infectious and immune-mediated diseases. The NIAID, Division of AIDS has a requirement for the synthesis of therapeutics directed against HIV and other infectious diseases as well as agents to serve and anti-HIV topical microbicides.

Description
This solicitation provides the resources for the synthesis of microbicides and compounds for the treatment of HIV, and other infectious diseases of relevance to the research agenda of NIAID. The contract will synthesize chemicals, in compliance with FDA's current Good Manufacturing Practice (cGMP) regulations if necessary, in quantities needed for testing in either in vitro screens, animals, or early Phase I clinical studies.

This is a 100% SMALL BUSINESS SET-ASIDE, NAICS 541712, with a size standard of 500 employees. The National Institute of Allergy and Infectious Diseases (NIAID) anticipates that one cost reimbursement, term (level of effort) type contract will be awarded for a one year base period of performance beginning on or about February 13, 2015. Options will be included to extend the term of the contract for an additional six years for a maximum period of performance of 7 years. The requirement will be for the delivery of 6.14 full time equivalents (FTEs) per year for the Base Period (Year 1) and each option period (Years 2 through 7).

Any responsible offeror may submit a proposal which will be considered by the Agency. This RFP will be available electronically on/about March 6, 2014, and may be accessed through FedBizOpps http://www.fedbizopps.gov/. This notice does not commit the Government to award a contract. No collect calls will be accepted. No facsimile transmissions will be accepted.

For this solicitation, the NIAID requires proposals to be submitted via two methods: (1)
Disc (CD or DVD) and (2) Online via the NIAID electronic Contract Proposal Submission (eCPS) website. The content of the disc and online proposals must be identical. Submission of proposals by facsimile or e-mail is not acceptable.

For directions on using eCPS, go to the website https://ecps.niaid.nih.gov and then click on "How to Submit."

To submit online using eCPS, offerors must have a valid NIH electronic Research Administration (eRA) Commons account, which provides authentication and serves as a vehicle for secure transmission of documents and communication with the NIAID. The eRA Commons registration process may take up to 4 weeks. For more information, please see http://era.nih.gov/applicants/how-to_steps.cfm#register."