Sorting of peripheral blood mononuclear cells (PBMCs) from Venezuelan Equine Encephalitis Virus (VEEV) survivors for The U. S. Army Medical Research Institute of Infectious Diseases (USAMRIID)

This solicitation seeks sorting services for peripheral blood mononuclear cells from survivors of Venezuelan Equine Encephalitis Virus. The U.S. Army Medical Research Institute of Infectious Diseases seeks to discover and produce monoclonal antibodies for in-vitro and in-vivo assessment against the virus. The contractor will isolate 50-300 human antibodies from provided samples by the base period end using cell sorting. Responses are due by September 16, 2022. Performance will be evaluated on antibody binding, competition grouping, material production, and assay completion according to the Quality Assurance Surveillance Plan.

There is no set-aside designation. The NAICS code is 541715 and PSC code is R425. Services will be performed at the contractor's facility with deliverables sent to Fort Detrick, Maryland. The base period requires sorting and initial screening, with optional periods to select lead candidates, produce material for rodent testing, and generate polyclonal pools and monoclonal antibodies for nonhuman primate studies. The non-disclosure agreement protects government and contractor information exchanged during performance.