Population Health Research Support

Added: Mar 12, 2018 2:46 pm Modified: Jul 12, 2018 9:33 amTrack Changes

Amendment 2 is posted with responses to additional questions from potential offerors.

Added: Mar 12, 2018 2:46 pm Modified: Jul 06, 2018 11:02 amTrack Changes

Amendment posted.

Added: Mar 12, 2018 2:46 pm Modified: Jun 27, 2018 1:57 pmTrack Changes

Response Dare entered.

Added: Mar 12, 2018 2:46 pm Modified: Jun 11, 2018 4:13 pmTrack Changes

The official solicitation is estimated to be posted to FedBizOpps on or about June 15, 2018.

Added: Mar 12, 2018 2:46 pm Modified: May 04, 2018 10:30 amTrack Changes

Attached is a DRAFT SOLICITATION for solicitation # NIH-NICHD-DIPHR-2018-12.

Please review the attached draft carefully.

Added: Mar 12, 2018 2:46 pm

THIS IS A RESEARCH AND DEVELOPMENT (R&D) NOTICE OF INTENT, NOT A REQUEST FOR PROPOSAL.

The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Division of Intramural Population Health Research (DIPHR) plans to compete and award a contract for population health research centers.

Background:

The is an intramural research division at the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) whose mission is to improve population health across the life course by maximizing health and preventing disease [http://www.nichd.nih.gov/about/org/DIPHR/Pages/default.aspx].  The Division comprises the Office of the Director along with three research branches: Biostatistics and Bioinformatics, Epidemiology, and Health Behavior.  As an intramural research entity, the Division designs and conducts innovative, high-risk research aimed at answering critical data gaps regarding human fecundity, reproduction and development; pregnancy and delivery, including adverse pregnancy outcomes; offspring health, growth and development from birth to adulthood, and adolescent behavior.  In addition, the Division conducts original methodologic research aimed at developing novel statistical tools for analytic purposes. 

Innovative and flexible research centers capable of implementing epidemiologic and behavioral research focusing on human reproduction; pregnancy; infant, child and adolescent health, growth and development; and human behavior are needed to assist the Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), in the successful completion of original population health research.  The breadth and complexity of population health research undertaken by Division investigators poses unique challenges with regard to several aspects: defining sampling frameworks that can be enumerated, incorporating varying units of analysis (e.g., individuals, menstrual or treatment cycles, couples, twins/siblings, families) into study designs; specifically targeted recruitment and retention of study participants; and longitudinal questionnaire data and biospecimen collection to capture of time-varying covariates and outcomes.  Of note is the hierarchical data structure generated by much of the Division’s research reflecting the recruitment of triads/dyads or genome wide analytic studies (GWAS) or multi-scale data from study participants (e.g., day, cycle, woman and couple level data collection for fecundity and fertility research, schools, census levels). 

Therefore, DIPHR aims to establish approximately three to five research support centers capable of implementing sophisticated initiatives, from preconception through adulthood, using scientifically valid and rigorous methodologies, to assist in the conduct of population health research initiatives.  It is anticipated that initially 1-2 new research (observational cohorts and/or intervention trials) initiatives would be implemented each year utilizing one or more centers per initiative. 

This RFP (NIH-NICHD-DIPHR-2018-12) will be electronically available on or about March 30, 2018 in draft form. The RFP may be accessed through the FedBizOpps website, https://www.fbo.gov. All responsible sources may submit proposals. This is not a request for proposals. This requirement is defined as code 541715 under the North American Industry Classification System (NAICS).