Notice of Intent to Sole Source - Schrodinger Suite License Renewal

SOLE SOURCE PROCUREMENT - The Division of Bioinformatics and Biostatistics(DBB) of the National Center for Toxicological Research (NCTR) of the Food and Drug Administration (FDA) is currently conducting research in computational chemistry. A crucial component of the research involves chemical structure analysis. We require the latest generation of chemical simulation software to provide us with comprehensive tools required for analysis of chemical structures, and quantitative structure-activity relationships (QSARs), as well as visual graphics, to enable our efforts in computational chemistry. The DBB has been utilizing the Schrödinger Suite chemical simulation software (Small Molecule Drug Discovery Suite) since 2012 at a cost of $230,000 to date.

The Schrödinger Suite chemical simulation software licenses (Small Molecule Drug Discovery Suite) are up for renewal. If these licenses are not renewed, the research in computational chemistry will be negatively impacted, as it will preclude NCTR's ability to continue the ongoing project that needs computational chemistry.
Job Orders shall be within scope, issued within ordering period, and be within the maximum total dollar value of approximately $32,500.00 for a one-year period and $130,000.00 for a total of one base period and 3 option periods.

• Chemical Simulation Software - Small Molecule Drug Discovery Suite

The proposed contract is for the supplies and services for which the Government intends to solicit and negotiate with one source, Schrodinger, LLC., 101 SW Main Street, Suite 1300, Portland, OR 97204 under authority of FAR 6.302-1 (statutory authority 10 U.S.C. 2304(c)(1)), Only One Responsible Source.
THIS NOTICE IS NOT A REQUEST FOR COMPETITIVE PROPOSALS, however, all responsible sources may submit a capability statement, proposal, or quotation, which shall be considered by the agency. However, a determination by the Government not to compete this proposed action based upon responses to this draft agreement is solely within the discretion of the Government. Information received will normally be considered solely for determining whether to conduct a competitive procurement.

All responses are due by Friday, May 24, 2019 at 12 noon. Responses may be sent to Erika Crawford at Erika.Crawford@fda.hhs,gov.

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