NIEHS Assessment of Immunotoxicity – In Vitro and In Vivo Assessment of Immune Function
Closed Pre-Solicitation Posted
- Solicitation number
- mmunotox_RFI_SSN_NIEHS_2023
- Agency
-
National Institute of Environmental Health Sciences
National Institutes of Health, Department of Health and Human Services
- Responses due
- Set-aside
- No set-aside
Opportunity facts
- NAICS code
- 541715 Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
- PSC
- AJ11 General Science And Technology R&D Services; General Science And Technology; Basic Research
- Place of performance
- Durham, North Carolina, United States
- Points of contact
Notice details come from SAM.gov. Updated .
About this opportunity
The National Institute of Environmental Health Sciences (NIEHS) within the National Institutes of Health is seeking a contractor to provide comprehensive immunotoxicity assessment services using in vitro and in vivo research methods. The primary objectives include evaluating chemical modulation of immune function through primary human cell screening, assessing potential chemical-induced hypersensitivity using in chemico or in vitro models, and conducting immunotoxicity research studies in adult mice, adult rats, and developing rats. The contract will require robust capabilities in developing and evaluating novel tools and methods for immune function assessment, with a focus on measuring humoral, cell-mediated, and innate immune endpoints. Interested parties must submit capability statements not exceeding 15 pages by August 9, 2023, detailing their technical expertise, relevant project experience, and comments on the draft statement of work. The government will use these submissions to conduct market research and determine potential sources for the upcoming contract.
The opportunity is designated for small businesses under NAICS code 541715 with a size standard of 1,000 employees, and no specific socioeconomic set-aside has been established. The anticipated contract is a cost-reimbursement type with an expected performance period of 10 years, consisting of a base year and nine option years. While specific budget details are not explicitly stated, previous amendments suggest an annual labor hour rate ranging between $8,000 to $12,000. The total contract value is expected to be significant, reflecting the comprehensive scientific research services required. The procurement will leverage multiple testing protocols, including sample protocols for in vivo studies using compounds like lycopene, to evaluate immunotoxicity across different exposure scenarios and animal models. Contractors must be prepared to comply with HHS, NIH, and NIEHS policies and regulations throughout the contract period.
Notice text
4 versions
Update #4 · Latest ·
12/16/2024 - A presolicitatoin notice for this requirement has been posted under ID Number: 75N96025R0001.
11/19/2024 Amendment 02 - See attached Amendment 02 Small Business Sources Sought Notice and related attachments. Request is only for small businesses to reply.
Amendment 01 - This combined RFI/SSN is amended to update the applicable NAICS code. Please see the attachments for the updated Combined RFI/SSN_Amend 01 file.
This is a combined request for information (RFI)/sources sought notice (SSN) only. Please see attachments for the Combined RFI/SSN.
Update #3 ·
11/19/2024 Amendment 02 - See attached Amendment 02 Small Business Sources Sought Notice and related attachments. Request is only for small businesses to reply.
Amendment 01 - This combined RFI/SSN is amended to update the applicable NAICS code. Please see the attachments for the updated Combined RFI/SSN_Amend 01 file.
This is a combined request for information (RFI)/sources sought notice (SSN) only. Please see attachments for the Combined RFI/SSN.
Update #2 ·
Amendment 01 - This combined RFI/SSN is amended to update the applicable NAICS code. Please see the attachments for the updated Combined RFI/SSN_Amend 01 file.
This is a combined request for information (RFI)/sources sought notice (SSN) only. Please see attachments for the Combined RFI/SSN.
Update #1 ·
This is a combined request for information (RFI)/sources sought notice (SSN) only. Please see attachments for the Combined RFI/SSN.
Files
Similar open opportunities
| Opportunity | Agency | Set-aside | Responses due |
|---|---|---|---|
| Pre-Clinical Models of Infectious Diseases | National Institute of Allergy and Infectious Diseases | No set-aside |
On GovTribe
Work this opportunity
- Track it in your pipeline
- Find teaming partners
- Similar opportunities
- Ask GovTribe AI about this opportunity