Mass Spectrometry-Based Untargeted Metabolomics Analysis - Wyndmoor, PA

The Department of Agriculture Agricultural Research Service (ARS) is soliciting mass spectrometry-based untargeted metabolomics analysis services through Solicitation 1232SA26Q0273. The contractor will analyze 258 filtered supernatant samples (177 samples from the first experiment and 81 from the second) using HILIC-LC-Orbitrap untargeted metabolomics acquisition across three analytical panels to identify over 1,000 validated compounds. Key requirements include at least two years of demonstrated experience with mass spectrometry-based untargeted metabolomics analysis, completion of analysis within 45 days of sample receipt, and provision of raw data files and methodologies that become sole property of USDA upon delivery. Results must include retention times, quantification masses, biochemical database identifiers, adduct information, and metabolite annotations with a minimum of four confidence rating levels. Award will be made to the highest technically rated offeror with acceptable or neutral past performance and fair and reasonable pricing on a firm fixed-price basis. The quote submission deadline is April 15, 2026 at 5:00 p.m. Central Time, and all pricing must be all-inclusive with pricing for all line items required to be considered responsive.

This is a total small business set-aside solicitation with a small business size standard of $19 million and NAICS code 541380 (Testing Laboratories and Services). No incumbent contractor is identified in the solicitation documents. The contract performance period runs from May 1, 2026 through April 30, 2027, with a delivery date of April 30, 2027, allowing flexibility for two independent sample shipments within the 12-month period. The specific dollar value or budget range for this firm fixed-price requirement is not disclosed in the solicitation notice. Place of performance is Glenside, PA (the USDA ARS Eastern Regional Research Center at 600 East Mermaid Lane, Wyndmoor, PA 19038), where samples will be shipped FOB Destination. Interested offerors should submit quotes electronically to shane.pope@usda.gov and include company name, point of contact, phone number, email address, and SAM.gov Unique Entity ID.