Health and Environmental Risk Assessment

Amendment 1 to this notice is being published to:

(1) Clarify that capability statement submissions should be through FedConnect vs. e-mail. If you encounter hardship in submitting through FedConnect you may inform us by e-mail, you may also e-mail any questions you have.

(2) Correct the statement regarding multiple awards. We have not made a determination on matters such as number of awards or contract type at this stage of the acquistion process, however, this reqirement is consiered a follow-on to EPA contract 68HERC19D003 which is a single award contract.

No other changes have been made to this notice.


THIS IS A SOURCES SOUGHT SYNOPSIS FOR WRITTEN INFORMATION ONLY. THIS IS NOT A SOLICITATION ANNOUNCEMENT FOR PROPOSALS AND NO CONTRACT WILL BE AWARDED FROM THIS ANNOUNCEMENT.

The Environmental Protection Agency (EPA) is performing a “market search” for small businesses in preparation for a future procurement. Information submitted in response to this notice is merely used for internal market research purposes and no feedback will be offered to the interested parties that submit capability statements.

This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding: (1) the availability and capability of qualified small business sources; (2) whether they are small businesses; HUBZone small businesses; service-disabled; veteran-owned small businesses; 8(a) small businesses; veteran-owned small businesses; woman-owned small businesses; or small disadvantaged; and (3) their size classification relative to the North American Industry Classification System (NAICS) code for the proposed acquisition. Your responses to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set-aside is possible.


The EPA has a need for a contractor to provide support for the development and evaluation of technologies, processes, and tools to prevent or reduce pollution of air, land, and water, and to restore ecosystems. The contract will be managed by the Contracts Branch in the Office of Administration and Research Support Extramural Management Division of the Office of Research and Development (ORD), however, contract support will be available to all ORD laboratories, Centers, and offices as well as other USEPA organizations that conduct research projects that could be supported under the scope of the Performance Work Statement (PWS).

Specific areas to be addressed in capability packages are as follows: (1) Conducting risk assessments on environmental stressors (i.e. physical, chemical, microbial, or other agent forms) and (2) developing state-of-the art methods, models, and guidance documents for human health and environmental risk assessment.

These tasks commonly require expertise in multiple disciplines such as: epidemiology, toxicology, pharmacology, physiology, pathology, microbiology, infectious disease epidemiology, public health, decision analysis, quantitative
dose-response assessment, quantitative uncertainty analysis, human health economics, exposure modeling, statistics, biostatistics, chemistry, ecology, environmental engineering, and mathematical modeling including
Benchmark Dose (BMD) modeling, physiologically-based pharmacokinetic (PBPK) modeling, exposure modeling, and computational toxicology modeling, as well as library science or information management, project/program management, technical and scientific writing and editing, and software or application development.

In many tasks, scientific needs are highly specialized, requiring expert personnel having the knowledge and ability to fully and critically evaluate study methodologies and results in the technical disciplines identified above. Analyses must be scientifically sound and sufficiently documented to withstand intensive critical examination and review by other experts in relevant disciplines. The successful contractor of any resultant contract will be expected to provide all necessary labor, materials, and facilities in support of the efforts delineated by the PWS.

Additional information regarding these tasks can be found in the DRAFT Performance Work Statement (PWS).

To be considered a potential source, a firm must demonstrate they have personnel expert in the relevant technical disciplines and capacity, materials, equipment and facilities to support the effort as delineated above. Firms classified as small can subcontract work to similarly situated entities (i.e. other small businesses) and include the capabilities of that potential small business team to demonstrate the respondent’s ability to perform the requirement. ANY INTERESTED FIRM may submit a capability statement which demonstrates the firm’s ability to perform the general support tasks described above.

The Government will review the qualifications of interested parties based on their responses regarding capability of performing the draft PWS.


It is anticipated that this requirement will result in a IDIQ type contract with the majority of the task orders issued as Time and Material (T&M) type with others issued on a Firm Fixed Price (FFP) basis. The estimated contract period of performance is 5 years.

Respondents are required to submit their capabilities statement via FedConnect no later than 4:00PM on Thursday, November 17, 2022. There is no charge to use FedConnect. (See https://www.fedconnect.net/Fedconnect). If you need technical assistance in registering or for any other FedConnect® function, call the FedConnect® Help Desk at (800) 899-6665 or email at support@fedconnect.net.

The respondent shall, at a minimum, address the following questions regarding its Company Profile and Capability Information. It is recommended that the respondent use the template below for the company profile.

A. Company Profile
1. Company name and address;
2. Affiliate information: parent company, joint venture partners, and potential teaming partners;
3. NAICS Code 541715 Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology) with a size standard of 1,000 employees
4. Two points of contact (names, titles, phone numbers and email addresses);
5. UEI number and CAGE Code, as registered in the System for Award Management (SAM) at http://www.sam.gov/:
6. Small Business designation/status under NAICS Code 541715 (must correlate with SAM registration):
_____ Small business _____ HUBZone _____ WOSB
_____ 8(a) _____ VOSB
_____ SDVOSB
_____ Small Disadvantaged Business


Standard company brochures will not be considered a sufficient response to this Sources Sought Synopsis. The EPA reserves the right to set these actions aside for small businesses. Inquiries related to this notice may be sent by email to Growney.matthew@epa.gov

THIS IS A SOURCES SOUGHT SYNOPSIS FOR WRITTEN INFORMATION ONLY. THIS IS NOT A SOLICITATION ANNOUNCEMENT FOR PROPOSALS AND NO CONTRACT WILL BE AWARDED FROM THIS ANNOUNCEMENT.

The Environmental Protection Agency (EPA) is performing a “market search” for small businesses in preparation for a future procurement. Information submitted in response to this notice is merely used for internal market research purposes and no feedback will be offered to the interested parties that submit capability statements.

This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding: (1) the availability and capability of qualified small business sources; (2) whether they are small businesses; HUBZone small businesses; service-disabled; veteran-owned small businesses; 8(a) small businesses; veteran-owned small businesses; woman-owned small businesses; or small disadvantaged; and (3) their size classification relative to the North American Industry Classification System (NAICS) code for the proposed acquisition. Your responses to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set-aside is possible.


The EPA has a need for a contractor to provide support for the development and evaluation of technologies, processes, and tools to prevent or reduce pollution of air, land, and water, and to restore ecosystems. The contract will be managed by the Contracts Branch in the Office of Administration and Research Support Extramural Management Division of the Office of Research and Development (ORD), however, contract support will be available to all ORD laboratories, Centers, and offices as well as other USEPA organizations that conduct research projects that could be supported under the scope of the Performance Work Statement (PWS).

Specific areas to be addressed in capability packages are as follows: (1) Conducting risk assessments on environmental stressors (i.e. physical, chemical, microbial, or other agent forms) and (2) developing state-of-the art methods, models, and guidance documents for human health and environmental risk assessment.

These tasks commonly require expertise in multiple disciplines such as: epidemiology, toxicology, pharmacology, physiology, pathology, microbiology, infectious disease epidemiology, public health, decision analysis, quantitative
dose-response assessment, quantitative uncertainty analysis, human health economics, exposure modeling, statistics, biostatistics, chemistry, ecology, environmental engineering, and mathematical modeling including
Benchmark Dose (BMD) modeling, physiologically-based pharmacokinetic (PBPK) modeling, exposure modeling, and computational toxicology modeling, as well as library science or information management, project/program management, technical and scientific writing and editing, and software or application development.

In many tasks, scientific needs are highly specialized, requiring expert personnel having the knowledge and ability to fully and critically evaluate study methodologies and results in the technical disciplines identified above. Analyses must be scientifically sound and sufficiently documented to withstand intensive critical examination and review by other experts in relevant disciplines. The successful contractor of any resultant contract will be expected to provide all necessary labor, materials, and facilities in support of the efforts delineated by the PWS.

Additional information regarding these tasks can be found in the DRAFT Performance Work Statement (PWS).

To be considered a potential source, a firm must demonstrate they have personnel expert in the relevant technical disciplines and capacity, materials, equipment and facilities to support the effort as delineated above. Firms classified as small can subcontract work to similarly situated entities (i.e. other small businesses) and include the capabilities of that potential small business team to demonstrate the respondent’s ability to perform the requirement. ANY INTERESTED FIRM may submit a capability statement which demonstrates the firm’s ability to perform the general support tasks described above.

The Government will review the qualifications of interested parties based on their responses regarding capability of performing the draft PWS.


It is anticipated that the contract will be multiple award IDIQ type contract with the majority of the task orders issued as Time and Material (T&M) type with others issued on a Firm Fixed Price (FFP) basis. The estimated contract period of performance is 5 years.

Respondents are required to submit their capabilities statement via FedConnect no later than 4:00PM on Thursday, November 17, 2022. There is no charge to use FedConnect. (See https://www.fedconnect.net/Fedconnect). If you need technical assistance in registering or for any other FedConnect® function, call the FedConnect® Help Desk at (800) 899-6665 or email at support@fedconnect.net.

The respondent shall, at a minimum, address the following questions regarding its Company Profile and Capability Information. It is recommended that the respondent use the template below for the company profile.

A. Company Profile
1. Company name and address;
2. Affiliate information: parent company, joint venture partners, and potential teaming partners;
3. NAICS Code 541715 Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology) with a size standard of 1,000 employees
4. Two points of contact (names, titles, phone numbers and email addresses);
5. UEI number and CAGE Code, as registered in the System for Award Management (SAM) at http://www.sam.gov/:
6. Small Business designation/status under NAICS Code 541715 (must correlate with SAM registration):
_____ Small business _____ HUBZone _____ WOSB
_____ 8(a) _____ VOSB
_____ SDVOSB
_____ Small Disadvantaged Business


Standard company brochures will not be considered a sufficient response to this Sources Sought Synopsis. The EPA reserves the right to set these actions aside for small businesses. Responses to the above should be submitted by email to Growney.matthew@epa.gov no later than November 17, 2022.