Genohub bison sequencing

The U.S. Geological Survey Office of Acquisitions and Grants seeks whole genome sequencing services for 400 bison samples, with quotations due September 21, 2026 at 12:00 PM Mountain Time. This is a Total Small Business set-aside procurement.

Place of performance is the USGS Fort Collins Science Center. The contractor must perform DNA extraction, library preparation, and next-generation sequencing at minimum 20X average coverage using Illumina NovaSeq or equivalent platforms, with all work completed within 20 weeks of sample receipt. Deliverables include demultiplexed FASTQ files and return of all unused sample materials. The contract type is Firm Fixed Price with a performance period from September 24, 2026 through September 23, 2027.

Quotations must include unit and total costs for DNA extraction (400 samples), library preparation (400 samples), and next-generation sequencing 2X150 paired-end chemistry (400 samples). The NAICS code is 541380, Testing Laboratories and Services; PSC code is R425, Support—Professional: Engineering/Technical.

Evaluation uses a best-value approach with three equally weighted or nearly equally weighted factors: Technical Capabilities (Factor 1), Past Performance (Factor 2), and Price (Factor 3, less important). Vendors must document sample processing capacity, DNA extraction/library preparation/sequencing methodologies, and provide three references for similar service contracts completed within the past five years. Award will be made to the lowest-priced, technically acceptable offeror.

Quotation submissions must include the completed SF-18 form, SAM.gov UEI Number, point of contact information, and completed FAR provision representations (52.209-2, 52.209-11, 52.219-1, 52.240-90). Contact Jennifer Rollin at jennifer_rollin@ios.doi.gov. Amendment 0001, effective September 13, 2026, increased the contract quantity from 200 to 400 samples and added FAR clause 52.219-6, Notice of Total Small Business Set-Aside. Offerors must acknowledge receipt of this amendment by the deadline.