Generation and fluorescent formatting of aptamers targeting antiretroviral drugs (ARVs) for the detection of unreported ARV use on behalf of the CDC’s National Center for HIV, Viral Hepatitis, STD, and Tuberculosis Prevention Division of HIV Prevention.
Closed Solicitation Posted
- Solicitation number
- CDC-7D301-NCHHSTP-0001
- Agency
-
CDC Office of Acquisition Services
Centers for Disease Control and Prevention, Department of Health and Human Services
- Responses due
- Set-aside
- No set-aside
Opportunity facts
- NAICS code
- 541715 Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
- PSC
- AJ12 General Science And Technology R&D Services; General Science And Technology; Applied Research
- Place of performance
- Atlanta, Georgia 30329, United States
- Points of contact
Notice details come from SAM.gov. Updated .
About this opportunity
The Centers for Disease Control and Prevention seeks generation and fluorescent formatting of aptamers targeting antiretroviral drugs for detection of unreported ARV use, with proposals due July 31. This is a sole-source procurement awarded to Texas A&M University under FAR 12.102(a), restricting competition.
Place of performance is Atlanta, Georgia. The period of performance runs two years from August 3, 2026 through August 13, 2028. Work supports the National Center for HIV, Viral Hepatitis, STD, and Tuberculosis Prevention Division of HIV Prevention and addresses limitations of liquid chromatography with tandem mass spectrometry—the current gold standard for ARV detection—which is costly, labor-intensive, and impractical for high-throughput or resource-limited settings. The aptamer-based approach enables efficient qualitative screening of priority ARVs for surveillance and blood safety monitoring at scale and in resource-constrained laboratory environments. NAICS code is 541715, Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology). PSC is AJ12, General Science and Technology R&D Services.
Notice text
This is a combined synopsis/solicitation for a sole-source requirement.
The Centers for Disease Control and Prevention (CDC) Office of Acquisition Services intends to award a sole source contract to Texas A&M University for services to provide generation and fluorescent formatting of aptamers targeting antiretroviral drugs (ARVs) for the detection of unreported ARV use on behalf of the CDC’s National Center for HIV, Viral Hepatitis, STD, and Tuberculosis Prevention Division of HIV Prevention.
Antiretroviral drugs (ARVs) are the foundation of HIV treatment and prevention. Detection of unreported ARV use is essential for surveillance, behavioral research, and blood safety monitoring. While liquid chromatography with tandem mass spectrometry (LC-MS-MS) remains the gold standard for ARV detection, it is costly, labor-intensive, and impractical for high-throughput or resource-limited settings. These constraints limit its scalability for high-throughput surveillance and preclude its use in many public health or resource-limited laboratory settings.
The Division of HIV Prevention Laboratory Branch (DHP LB) at the CDC is developing a high-throughput assay that leverages aptamer-based technologies and plate-based detection to enable efficient qualitative screening of ARVs that are priorities for surveillance and blood safety monitoring.
The anticipated period of performance for a two-year multi-year contract from 8/03/2026 through 8/13/2028.
The NAICS Code is: 541715 - Research and Development Laboratories or Services (except Biotechnology and Nanotechnology Research and Development)
The PSC is: AJ12 – General Science and Technology R&D Services
As indicated above, this contract action is for services for which the Government intends to solicit and negotiate with only one source under the authority of Revolutionary FAR Overhaul 12.102(a), Restricting competition.
No solicitation will be published for this requirement. This notice is issued solely to determine whether there are any responsible sources capable of meeting the Government’s requirements.
Interested parties may identify their interest and submit documentation of their capability to respond to this requirement. This notice of intent is not a request for competitive quotations/proposals; however, all responses received within the issuance period of this notice will be considered by the Government. A determination by the Government not to competitively solicit for the proposed contract action based upon responses to this notice is solely within the discretion of the Government. Information received will normally be considered solely for the purpose of determining whether to conduct a competitive procurement.
Responses should be emailed to the Contracting Officer, Serina Allingham, xog9@cdc.gov, by 5:00p.m. on July 31, 2026.
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