Contract Research Organization - For the Housing, Care and Support of Nonhuman Primate Biomedical Research

Q&A Amendment

Q1) Can we use client's caging if needed?

A1) Yes, the client's caging can be used if needed. However the vendor will have to have the appropriate equipment to clean the caging properly; assumption is the vendor has a cage-washer. We would prefer if the vendor has caging to supplement our donated caging.

Q2) Can we get further clarification on what is required for the Blood Transfusion in sedated NHP, possibly some examples?

A2) Blood taken from a fully sedated donor animal (previously typed for cross-match) from a (maximum of 12.5% blood every 30 days) is combined with 10% citrate, rocked, and kept on ice during transport to USUHS. The blood is then irradiated with 2500 cGy utilizing the Walter Reed Hospital irradiator. Blood donor animals will have a CBC done prior to donation to confirm the absence of anemia.

Whole blood will be transfused if PLT counts are less than 20,000/uL and hemoglobin concentrations are less than 7g/dL or the hematocrit is less than 20%.

Packed RBCs will be administered in preference to whole blood if platelet counts are greater or equal to 100,000/uL with no signs of clinical bleeding.

Blood will be transfused into the fully sedated recipient (previously blood typed) via a blood infusion pump (syringe type) or manually via syringe and infusion set through the cephalic vein, saphenous vein, or some other peripheral vessel.

Animals will be visualized during and after the process for presence of a infusion reaction.

Q3) What is the typical duration of a primate study?

A3) The typical duration for any cohort of a primate study is 60-90 days.

Q4) Are attachments acceptable on this proposal?

A4) yes as long as you stay within stated page limitations

This amendment also extends the due date for quotes.

Quote packages are due by 5:00 p.m. Eastern Local Time on 29 August 2017. Quotes must be submitted via email to carolyn.randolph@usuhs.edu. Quotes will not be accepted by any other means. Late quotes will not be considered. Offerors will receive an email confirmation that their quote was received and whether it was on time or late within two (2) business days.

Quote packages should include a cover sheet that provides the following information:

• Company Name
• Point of Contact, to include email and phone number
• DUNS Number
• Statement that includes acknowledgement of latest amendment number (if applicable). Failure to acknowledge the most recent amendment number, may render an offeror's quote non-responsive.

The Uniformed Services University of the Health Sciences (USU) is the Nation's federal health sciences university and is committed to excellence in military medicine and public health during peace and war. We provide the Nation with health professionals dedicated to career service in the Department of Defense and the United States Public Health Service and with scientists who serve the common good. We serve the uniformed services and the Nation as an outstanding academic health sciences center with a worldwide perspective for education, research, service, and consultation; we are unique in relating these activities to military medicine, disaster medicine, and military medical readiness. USU is located in Bethesda, MD on the grounds of the Naval Support Activity Bethesda.

Additional information regarding USU can be found on our website: www.usuhs.mil.

USU has a requirement to establish a three (3) year single-award Blanket Purchase Agreement (BPA) for services of a Contract Research Organization - for the Housing, Care and Support of Nonhuman Primate Biomedical Research.

These services have not been previously procured.

This is a combined synopsis/solicitation for commercial items in accordance with the format in FAR Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; quotes are being requested and a written solicitation will not be issued. This is a request for quotes (RFQ) for commercial items in accordance with the procedures of FAR Part 12 - Acquisition of Commercial Items and FAR Part 13 - Simplified Acquisition Procedures, to include FAR Subpart 13.5, Simplified Procedures for Certain Commercial Items. This RFQ incorporates all provisions and clauses in effect through Federal Acquisition Circular (FAC) 05-95 (January 19, 2017) and Defense Federal Acquisition Regulation Supplement (DFARS) (December 22, 2016).

In order to be eligible for award, offerors must be registered in www.SAM.gov, with completed representations and certifications by the close date of the solicitation.

Offerors interested in responding to this requirement must provide a quote for the requested services outlined in the statement of work. A single-award three (3) year BPA will be awarded.

See attached RFQ for complete statement of work and submission requirements.

Provisions and Clauses are attached.