Biomatik Peptide Synthesis

Sources Sought #1132563-SS

This is a Sources Sought notice Only.  This is NOT a solicitation for proposals, proposal abstracts, or quotations.  This Sources Sought is issued for information and planning purposes only as part of USDA ARS market research and does not itself constitute an RFQ.

Background

The Heck Lab, located in Ithaca, NY on the Cornell campus, needs to purchase peptides to use with citrus greening research. These synthesized peptides are critical in the progression of research for the lab and we have used them in smaller scale in the past with good results. As the research is expanding, we need larger quantities of these peptides to continue our progress.

Requirements

Because it is critically important that the peptides are of exact configurations, we require the following:

Gross weight: 3g or more

Purity: >98%

N-Terminus: Acetylation

C-Terminus: Amidation

TFA Removal: Switch to Acetate salt, with TFA <1% guarantee

Solubility Test: 1.0mg peptide soluble in 0.5ml DMSO P201019-SJ803531

Schedule of Line Items:

1. Peptide Name: NCR_803364

Sequence: VKCVLPRIARCIKYRCQCRN

1. Peptide Name: NCR_803531

Sequence: LYCNVGSHMECVKHQCKCIK

1. Peptide Name: NCR_803543

Sequence: RGCKRDKDCPQFRGVNIRCR

1. Peptide Name: NCR_803570

Sequence: YSSCATKEECKCPDNKRPAC

1. Peptide Name: NCR_803629

Sequence: QNLCVGSPLPLQCLKFICRC

1. Peptide Name: Mastoparan-VT4

Sequence: INLKAIAPLAKKLL

1. Peptide Name: Protopolybia-MPI

Sequence: INWLKLGKKVSAIL

1. Peptide Name: Protopolybia-MPIII

Sequence: INWLKLGKAVIDAL

1. Peptide Name: EMP-ER

Sequence: FDIMGLIKKVAGAL

1. Peptide Name: EMP-AF

Sequence: INLLKIAKGIIKSL           

Deliverables:

The company synthesizing these peptides must make a try for dissolving to 20 mg/mL in potassium phosphate buffer (~pH 5.5), even if they cannot guarantee the result.

ADVANCE NOTICE: Must notify when the items have shipped. The shipment cost must include any customs charges.

The Contractor Shall:

This Sources Sought is only for the purpose of identifying potential sources as part of USDA ARS market research. The Government does not intend to make an award based on responses to this inquiry. This notice does not constitute a commitment by the Government.

Responses to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set-aside is possible.  

The purpose of this notice is to obtain information regarding the availability and capability of qualified sources including any Small Businesses; HUBZone small business; service-disabled, veteran-owned small business; 8(a) small business; veteran-owned small business; woman-owned small business; or small disadvantaged businesses. Please state if you are a large business or a small business according to the NAICS code listed in this Sources Sought.

All information submitted in response to this announcement is voluntary, and the Government will not pay for information requested nor will it compensate any respondent for any cost incurred in developing information provided to the Government.

Any organization responding to this notice should ensure that its response defines how it can specifically meet the specifications for the items requested.  Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted.  After reviewing the responses received, a Combined Synopsis solicitation notice may be published on Sam.gov.

Submit the Following:

• Capability Statement and/or product descriptions that demonstrate your ability to meet all of the specific requirements, including Company Contact Info.
• SAM.gov UEI Number.
• Identify if you are a large business or a small business with NAICS 541380.

Original Point of Contact: All responses to this Sources Sought Notice must be received by July 30, 2024, by 2:00 PM EST, the specified due date and time to be considered. 

Email responses to Rebecca Lumpkin at rebecca.lumpkin@usda.gov.

Responses will not be returned. Responders are solely responsible for all expenses associated with responding to this Inquiry.

Do not submit pricing information in response to this Request.