AN21 - Health Research and Developmental Services; Health Research and Training; Basic Research
Closed Solicitation Posted
- Solicitation number
- N0018924QZ406
- Agency
-
Naval Supply Systems Command
Department of the Navy, Department of Defense
- Responses due
- Set-aside
- No set-aside
Opportunity facts
- NAICS code
- 541720 Research and Development in the Social Sciences and Humanities
- Points of contact
Notice details come from SAM.gov. Updated .
About this opportunity
Paragraph 1:
The Naval Submarine Medical Research Laboratory (NSMRL) is seeking research and developmental services to conduct an applied biomarkers study on decompression stress in U.S. Navy divers. The primary objective is to identify substances in the exhaled breath of divers that are associated with decompression stress. NSMRL will provide the contractor with de-identified, coded samples of exhaled breath condensate and volatile organic compounds collected from the divers during both decompression dives and normobaric control conditions. The contractor will be responsible for analyzing these samples. There is no set-aside designation for this opportunity, and the solicitation has a due date of August 12, 2024.
Paragraph 2:
This is an open competition, and there is no information provided on potential incumbent contractors. The award value and budget range are not specified. The study will involve up to 14 U.S. Navy divers as test subjects, and the place of performance will be at the NSMRL facilities.
Notice text
The Naval Submarine Medical Research Laboratory (NSMRL) is interested in understanding the physiological
responses to decompression stress. To that end, NSMRL plans to conduct dry hyperbaric experiments with up to 14
U.S. Navy divers as test subjects during which they will be exposed to a dive profile that is expected to produce
venous gas emboli (VGE). As VGE are filtered by the lungs, it is possible that biomarkers of this decompression
stress may be evident in the exhaled breath of the divers following decompression. Thus, one of the primary aims of
the NSMRL study entitled Applied Biomarkers of Decompression Stress is to identify substances in exhaled
breath that are associated with decompression stress.
To do this, NSMRL researchers will collect exhaled breath
condensate (EBC) immediately before the dive and at two time points post-dive. These EBC samples will be
compared to a control condition in which the same divers breathe a normobaric nitrox gas mixture (with the PiO2
matched to the decompression dive) that will not produce any VGE. During both the decompression dive and the
control condition, will also collect breath samples on thermal desorption tubes pre- and post-dive at the same
time points, as well as gas sample controls to allow for analysis of the volatile organic compounds in exhaled breath.
NSMRL will be responsible for securing human use approval prior to conducting the study and will supply all EBC
and VOC samples to the awarded contractor as de-identified coded samples.
Description of tasks in attached synopsis.
Similar open opportunities
| Opportunity | Agency | Set-aside | Responses due |
|---|---|---|---|
| Broad agency announcement - biomedical research and diving equipment development | Naval Sea Systems Command | No set-aside |
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