AJ11--Synthesis of Cyclic Peptide NPC86
Closed Special Notice Posted
- Solicitation number
- 36C24826Q0987
- Agency
-
Veterans Integrated Service Network 8
Veterans Health Administration, Department of Veterans Affairs
- Responses due
- Set-aside
- No set-aside
Opportunity facts
- NAICS code
- 541715 Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
- PSC
- AJ11 General Science And Technology R&D Services; General Science And Technology; Basic Research
- Points of contact
Notice details come from SAM.gov. Updated .
About this opportunity
The James A. Haley VA Medical Center, part of the Department of Veterans Affairs Veterans Health Administration, issued a Special Notice on July 23, 2026 announcing a sole-source intent to Curia Global Inc. for non-GMP synthesis of NPC86, a cyclic peptide designed to treat metabolic diseases including Type 2 Diabetes and neurodegenerative diseases, with responses due by July 28, 2026 at 10:00 AM EST.
The requirement calls for synthesis of 2 grams of NPC86 using Solid Phase Peptide Synthesis (SPPS) methodology on Rink amide resin, targeting 95% purity by HPLC (area%, non-validated). Performance runs from August 17, 2026 through August 16, 2027. The work is classified under NAICS 541715 (Research and Development in the Physical, Engineering, and Life Sciences) and PSC AJ11 (General Science and Technology R&D Services).
Interested parties must submit a letter from the manufacturer stating authorization to work with Curia Global Inc. by the July 28 deadline. The notice is issued for information and planning purposes only and does not constitute a binding solicitation; responses are not offers and cannot form a contract. Responders bear all response expenses. The contracting office is located at 8875 Hidden River Parkway, Suite 160A, Tampa, Florida 33637.
Notice text
Special Notice
Special Notice
Page 4 of 4
Non-GMP Synthesis of NP-C86 (Cyclic Peptide)
James A. Haley VA Medical Center, 13000 Bruce B. Downs Blvd., Tampa, Florida 33612, intends to solicit sole source to Curia Global Inc., for the NPC86 which is a new drug designed to alleviate metabolic diseases such as T2D and neurodegenerative diseases. The chemistry to synthesize the drug is highly specialized and uses the solid state synthesis method. The target is to synthesize 2 grams of NPC86 which is acyclic peptide.
Curia will use Solid Phase Peptide Synthesis (SPPS) for this peptide, initiating the synthesis on Rink amide resin. This approach will yield an amide functionality at the C-terminal upon cleavage. The target specification for the final compound is 95% purity by HPLC (area%, non-validated).
Period of performance is 8/17/2026 to 8/16/2027. The North American Industry Classification System (NAICS) code is 541715, Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology).
Any information regarding this requirement must be received no later than 7/28/2026 @ 10:00 AM EST. Please provide a letter from the manufacturer stating authorization to work with Curia Global Inc.
DISCLAIMER
This request for information is issued solely for information and planning purposes only and does not constitute a solicitation. All information received in response to this request for information that is marked as proprietary will be handled accordingly. In accordance with FAR 15.201(e), responses to this notice are not offers and cannot be accepted by the Government to form a binding contract. Responders are solely responsible for all expenses associated with responding to this RFI.
Files
| File | Type | Posted |
|---|---|---|
| 36C24826Q0987.docx | DOCX document |
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