AAV AQP1 Study Prevention of radiation induced xer
Closed Solicitation Posted
This opportunity was awarded. See the award notice from .
- Solicitation number
- 75N92023R0178
- Agency
-
National Heart Lung and Blood Institute
National Institutes of Health, Department of Health and Human Services
- Responses due
- Set-aside
- No set-aside
Opportunity facts
- NAICS code
- 541940 Veterinary Services
- PSC
- 8820 Live Animals, Not Raised For Food
- More information
Notice details come from SAM.gov. Updated .
About this opportunity
This solicitation seeks proposals for an AAV AQP1 study to prevent radiation induced xerostomia in minipigs by administering AAV AQP1. The National Heart, Lung and Blood Institute of the Department of Health and Human Services will evaluate proposals to determine the effectiveness of gene therapy using an adeno-associated virus vector containing the aquaporin-1 gene to reduce damage to salivary glands from radiation therapy. Proposals are due by March 22, 2023 and will be evaluated based on the offeror's technical approach, qualifications, and price.
There is no set-aside designation for this requirement. The primary NAICS code is 541715 and PSC code is R425. As the incumbent, the National Institutes of Health will likely perform the research internally with a budget under $150,000. The place of performance will be the NIH facilities in Bethesda, Maryland. Up to 10 minipigs will be used over a 12 month period to assess changes in salivary flow rates and gland histology at regular intervals post-radiation and gene therapy administration.
Notice text
AAV AQP1 Study Prevention of radiation induced xerostomia in minipigs by administering AAVAQP1
Notice history
| Notice | Type | Posted |
|---|---|---|
| AAV AQP1 Study Prevention of radiation induced xerostomia in minipigs by administering AAVAQP1 | Award Notice | |
| This notice | Solicitation |
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