6640--534-20-3-8195-0177 Fluorescence Microscope (VA-20-00056078)

This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in FAR Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; quotes are being requested and a written solicitation will not be issued. This is a Request for Quote (RFQ) and the solicitation number is 36C24E20Q0160. The government anticipates awarding a firm-fixed price contract resulting from this combined synopsis/solicitation. This solicitation is issued as a 100% set aside for small business concerns. It is the responsibility of the contractor to be familiar with the applicable clauses and provisions. The clauses may be accessed in full text at www.acquisition.gov.

STATEMENT OF NEED (SON)

CONTRACT DESCRIPTION AND REQUIREMENTS

The Charleston VA Medical Center has a requirement to purchase a Keyence BZ-X810 All-in-one Fluorescence Microscope for the Research Department. A firm-fixed price contract will be awarded for the purchase of Brand Name or Equal equipment in accordance with all terms, conditions, provisions, specifications and schedule of this solicitation herein. Quotes shall contain the Offeror s best terms for cost/price and technical capabilities of the required Keyence or equivalent equipment. The government reserves the right to award without discussions.

1.1 PRICING

The Offeror shall submit price quotes for the required brand name or equal equipment, to the specifications listed in Section 1.2 below. Please enclose the established price list and description of capabilities and product specifications for the required equipment. The Offeror shall submit a separate price sheet for equal items to include Manufacturer Name, Stock/Part #, Unit of Issue and Price. Items offered that are brand name or equal shall identify items as being on GSA schedule and reference the contract number for each item.

Note: The Offeror should include a description of any support services or warranty information in the technical quote.

1.2 REQUIRED PRODUCTS & SPECIFICATIONS

Keyence BZX Fluorescence Microscope, or equal, equipment in support of funded research projects.

ITEM INFORMATION

ITEM NUMBER

DESCRIPTION OF SUPPLIES/SERVICES

QUANTITY

UNIT

0001

BZX Fluorescence Microscope BZX Microscope Head

STOCK NUMBER: BZ-X810

1.00

EA

0002

BZX Microscope Controller

STOCK NUMBER: BZ-X800E

1.00

EA

0003

BZ Support Package

STOCK NUMBER: BZ SUPPORT PACKAGE

1.00

EA

0004

BZX Hardware Module BZX Multi-Stack Module

STOCK NUMBER: BZ-H4XD

1.00

EA

0005

BZX Hardware Module BZX Sectioning Module

STOCK NUMBER: BZ-H4XF

1.00

EA

0006

KIW F1(FOR 5PER PRE-MIXED) TOKAIHIT Tokai Hit Por 5% Pre-mixed

STOCK NUMBER: 972083

1.00

EA

0007

BZX Hardware Module BZX Time Lapse Module

STOCK NUMBER: BZ-H4XT

1.00

EA

0008

BZX Software BZX Analyzer Software

STOCK NUMBER: BZ-H4A

1.00

EA

0009

BZX Software BZX Hybrid Cell Count Software

STOCK NUMBER: BZ-H4C

1.00

EA

0010

BZX Software BZX Macro Cell Count Software

STOCK NUMBER: BA-H4CM

1.00

EA

0011

BZX Software BZX Measurement Module

STOCK NUMBER: BZ-H4M

1.00

EA

0012

BZX Accessory BZX DAPI Filter

STOCK NUMBER: OP-87762

1.00

EA

0013

BZX Accessory BZX GFP Filter

STOCK NUMBER: OP-87763

1.00

EA

0014

BZX Accessory BZX Texas Red Filter

STOCK NUMBER: OP-87765

1.00

EA

0015

BZX Accessory BZX Cy5 Filter

STOCK NUMBER: OP-87766

1.00

EA

0016

BZ NIKON OBJECTIVE LENS (2X) CFI PLAN APO 2X LAMBDA

STOCK NUMBER: 972029

1.00

EA

0017

BZ NIKON OBJECTIVE LENS (10X) CFI PLAN APO 10X LAMBDA

STOCK NUMBER: 972031

1.00

EA

0018

BZ NIKON OBJECTIVE LENS (20X) CFI PLAN APO 20X LAMBDA

STOCK NUMBER: 972032

1.00

EA

0019

BZ NIKON OBJECTIVE LENS (40X PHASE) CFI S PLAN FLUOR ELWD ADM 40X

STOCK NUMBER: 971963

1.00

EA

0020

BZ NIKON OBJECTIVE LENS (60X OIL) CFI PLANAPO60XH LAMBDA

STOCK NUMBER: 972036

1.00

EA

0021

Win10 PC for BZ-X800

STOCK NUMBER: 972326

1.00

EA

0022

IMMERSION OIL 971806 IMMERSION OIL

STOCK NUMBER: 971806

1.00

EA

0023

TRAINING AND SUPPORT PKG

STOCK NUMBER: BZSUPPORTPKG

1.00

EA

0024

SHIPPING

1.00

EA

1.3 Product Capabilities & Salient Characteristics or equal:

The all-in-one system requested will make possible confocal, high-throughput, live-cell and whole-section imaging of cells and tissue in a single, self-contained, dynamic system. Its addition will expand and advance current imaging capabilities of the VA Research, to include high-resolution fluorescence, differential interference contrast, IR-differential interference contrast, phase contrast, relief contrast, simple polarized, brightfield, and darkfield observation methods of normal and diseased tissues and cells. A strength of the BZ-X810 system is its versatility it can accommodate a variety of specimen holders, including slides, dishes, and well plates, making it ideal for a multitude of studies that span fluorescent imaging of cellular/molecular phenotype to whole slide imaging of normal vs. diseased organ tissue in small animal models. This system is also well equipped for live cell imaging over many hours-days, making possible long-term observation of changes in cellular phenotype at a frame rate of 95 fps, as well as functional molecular/cellular assays. With a built-in dark room environment and compact footprint, the BZ-X810 will be an economical and practical addition to the VA Imaging & Microscopy Core, which is a Shared Resource Facility providing multiple types of shared instrumentation.

Fully enclosed, inverted-type microscope with the following features:

Compact frame

Built-in darkroom (fully-contained stage) necessary for fluorescent imaging

This system will be installed in a Shared Resource Facility where a darkroom environment cannot be maintained due to the use of other equipment in the space. The instrument must have a fully contained stage, achievable without the addition/removal of a separate apparatus, as this is not practical for shared instrumentation that will be used daily by numerous investigators.

Built-in vibration dampening system to reduce fluorescent blurring and background introduced by external noise

Observation methods: fluorescence (blue, green ultraviolet excitations), differential interference contrast, IR-differential interference contrast, phase contrast, relief contrast, simple polarized light, brightfield, darkfield, live-cell

High resolution observation deep into live cells

Multi-stack module for full automation of z-stacking and for seamlessly stitching whole sections

Sectioning module for optical sectioning, to produce confocal-quality images

Time-lapse module for stage-top incubation to control temperature, CO2, and humidity and image over hours-days with focus tracking and the ability to change capture conditions including location of interest, exposure time, focus, z stack, lens magnifications and filters

Live-cell incubator and imaging

Tokai hit 5% CO2 system for optimal, controlled stage-top incubation of samples (including multi-well plates) and live-cell imaging with video recording at a frame rate of 95 fps

Integrated workstation with software for analysis

General analysis module for post-imaging adjustments (deconvolution, annotations, etc.)

Hybrid cell counting module for quantification of cells, measurements of area, brightness (intensity of excitation), major axis, minor axis, etc. using brightfield, phase and fluorescence imaging

Macro cell counting module for quantification of up to 400 fields of view at a single time and for automatic counting on multiple image files in a batch under the same condition based on a user-tailored conditions file; must also be compatible with live-cell imaging for high-precision quantification of video and time lapse recordings

Measurement module for 3D rendering, 3D measurement and volumetric analysis

Optical sectioning module for customization of structured light projections and rasterization of these patterns across each focal plane, allowing for subtraction of out-of-focus fluorescence light and optimal signal output for high resolution 3D models

Ability to integrate with Akoya s CODEX technology for high-parameter (> 40 markers) imaging and analysis

Training and support

Onsite training upon installation

Follow-up onsite training for advanced applications, 3-6 months after installation

Training, as needed, for the lifetime of the microscope

The product capabilities and salient characteristics identified above by a brand name or equal" description are intended to be descriptive, not restrictive, and to indicate the quality and characteristics of the product that will be satisfactory. Quotes offering "equal" products (including products of the brand name manufacturer other than the one described by the brand name) will be considered if such product is clearly identified in the quote and is determined by the VA to meet fully the salient characteristics on above products. If offering an equivalent product, the brand name of the equivalent product shall be clearly identified in the quote. Unless visibly identified as an equivalent product, offered items shall be considered as the brand name product referenced in this announcement.

The evaluation of quotes and the determination as to the equality of the products shall be the responsibility of the Government and shall be based on information provided by the Offeror. The Government is not responsible for locating or securing any information not provided in the quotation by the Offeror. To ensure that sufficient information is available, the Offeror must furnish, as a part of the quote, all descriptive material necessary for the purchasing activity to determine whether the products meet the salient characteristics of this requirement. Vendors proposing to modify a product to make it conform to the requirements of this announcement shall include a clear description of the proposed modification and clearly mark any descriptive material to show the proposed modification. Offers that do not have descriptive material will not be considered for award.

Instructions to the Offeror

Basis for award resulting from this RFQ will made to the Best Value Offer that provides a complete package pursuant to the preparation requirements set forth in 52.212-1. FAR 52.212-2 (Evaluation- Commercial Items) will be incorporated in full text into the RFQ and will be evaluated on the following factors. Evaluations will be in accordance with FAR 13 Simplified procedures.

Evaluation Factors for Award:

Factor 1 - Technical Capabilities

All offerors must meet or exceed all requirements and salient features as listed in the Statement of Need.

Factor 2 - Past Performance - Past Performance will be based on the most current PPIPRS

Report.

Factor 3 - Price

The following FAR provision and clauses apply to this solicitation and are incorporated by reference. The solicitation document, incorporated provision and clauses are those in effect through the Federal Acquisition Circular (FAC) 2005-89, Effective July 2, 2015. It is the responsibility of the contractor to be familiar with the applicable clauses and provisions. The clauses may be accessed in full text at www.acquistion.gov. This contract incorporates one or more clauses by reference, with the same force and effect as if they were given in full text. Upon request, the Contracting Officer will make their full text available.

FAR 52.212-1 Instructions to Offerors Commercial

FAR 52.212-2 Evaluation- Commercial Items

FAR 52.212-3 Offeror Representations and Certifications

FAR 52.212-4 Contract Terms and Conditions

FAR 52.212-5 Contract Terms and Conditions Required To Implement Statutes Or Executive Orders Commercial Item

FAR 52.219-6 Notice of Total Small Business Set-Aside (Nov 2011)

FAR 52.219-8 Utilization of Small Business Concerns (Oct 2014)

FAR 52.233-3 Protest After Award (Aug 1996)

FAR 52.211-6 Brand Name or Equal

FAR 52.233-2 Service of Protest

Quotes shall be submitted via email to millicent.covert@va.gov and Offerors must reference Solicitation 36C24E20Q0160 in the subject line of the email. No telephone request for information will be considered. Incomplete packages will be considered nonresponsive. All offers must be received by the closing date Monday, June 22, 2020, NLT 11:59 AM EST.