W81XWH22Q0067 Amendment 0003.pdf

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Microbiome Sequencing and Analysis Services
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W81XWH22Q0067
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W81XWH22Q0067-0003

Amendment W81XWH22Q0067-0003

The purpose of Amendment W81XWH22Q0067-0003 is to add Section B which was previously omitted. The CLIN structure has changed to allow for revised pricing and a sixty (60) month ordering period. The delivery information has changed to include a Period of Performance of sixty (60) months rather than a five-year ordering period with options. Finally, the follow ordering clauses are included by full text: 52.216-18, 52.216-19 and 52.216-22.

See changes below.

SECTION B

B.1 This requirement is for the procurement of Microbiome Sequencing and Analysis Services. The contractor is expected to provide the aforementioned Microbiome Sequencing and Analysis Services for the duration of the requested five-year ordering period of performance (POP).

B.2. This is an Indefinite-Delivery, Indefinite-Quantity (IDIQ) contract award, as identified under FAR 16.504(c).

Delivery Orders will be awarded on a Firm Fixed Price (FFP) basis.

B.3. Notice of Individuals Authorized to Purchase Under the IDIQ: The USAMRAA Contracting Officer and Government Purchase Card (GPC) Ordering Officers will be the only authorized buyers under this IDIQ.

USAMRAA will be authorized to place Delivery Orders for other agencies within the Department of Defense Medical Community, as needed. Orders by other individuals will not be honored without prior written approval from the USAMRAA Contracting Officer. The following offices are hereby authorized to place orders under this

IDIQ:

• U.S. Army Medical Research Acquisition Activity (USAMRAA)

• US Army Research Institute of Environmental Medicine (USARIEM)

B.3.1 Individual(s) Authorized to Purchase utilizing a Government Purchase Card (GPC) up to $25,000.00:

TBD at Time of Award

USARIEM

B.4. The Contracting Officer will order against the contract through issuance of Delivery Orders via a DD Form 1155 or SF1449 signed by the Contracting Officer. Delivery Orders will be executed in writing by the Contracting Officer and transmitted either via facsimile or electronically via e-mail. The contractor shall acknowledge receipt via e-mail.

B.5. Each Delivery Order will contain at a minimum the following information:

a. The date of order

b. Contract number and order number

c. Description of the requirement

d. Pricing Information

e. The period of performance/ delivery date

f. Accounting and appropriations data

g. Payment office address

h. Invoicing and acceptance instructions

i. Any other pertinent data

B.6. The ordering period begins with the initial start of contract and is estimated to be 60 months. The ordering period will end before 60 months if maximum dollar value of $850,000.00 is reached.

B.7. Contract Minimum/Maximum values The minimum contract value for all orders issued against this contract shall not be less than $1,000.00. The maximum contract value for all orders issued against this contract shall not exceed the maximum contract value of $850,000.00.

ITEM NO SUPPLIES/SERVICES MAX

QUANTITY

UNIT UNIT PRICE AMOUNT

0001 DNA Extraction

1250 $ $

ID/IQ

To include Consultation FOB: Destination

PSC CD: Q301

NET AMT $

UNIT UNIT PRICE AMOUNT

0002 20,000-30,000 reads/sample for 16s sequencing including library preparation, mock communities & quality control

FFP

To include Consultation

UNIT UNIT PRICE AMOUNT

0003 Metagenome sequencing 5-10Gb including library preparation, mock communities & quality control

To include Consultation

UNIT UNIT PRICE AMOUNT

0004 Custom bioinformatics services for 16S sequencing using validated procedures and databases and incorporation of quality control steps that include taxonomy tables at phyla, family, genus, and when possible, species level-resolution with read counts and relative abundances and assigned taxonomies;

Rarefaction plots, Alpha diversity metrics (observed ASVs, Shannon, Simpson) and Beta diversity metrics (Bray-Curtis, weighted and unweighted UniFrac)

To include Consultation

UNIT UNIT PRICE AMOUNT

0005 Custom bioinformatics services for metagenome sequencing using validated procedures and databases and incorporation of quality control steps that include taxonomy tables at phyla, family, genus, species level-resolution with read counts and relative abundances and assigned taxonomies; tables with identified genes, gene families, gene pathways and functional annotations with associated read counts; Rarefaction plots, Alpha diversity metrics (observed ASVs, Shannon, Simpson) and Beta diversity metrics (Bray-Curtis, weighted and unweighted UniFrac).

To include Consultation

UNIT UNIT PRICE AMOUNT

0006 Biostatistics services for 16S sequencing that include statistical modelling of comparisons between groups to include longitudinal modelling of between group comparisons over time using appropriate statistical models in accord with best practice recommendations.

To include Consultation

UNIT UNIT PRICE AMOUNT

0007 Biostatistics services for metagenomics sequencing that include statistical modelling of comparisons between groups to include longitudinal modelling of between group comparisons over time using appropriate statistical models in accord with best practice recommendations.

To include Consultation

UNIT UNIT PRICE AMOUNT

0008 Advanced biostatistics services including multi-omics data integration to assess relations between multi-omics data sets to include longitudinal relations using best practice recommendations.

To include Consultation

UNIT UNIT PRICE AMOUNT

0009 Absolute abundance quantification

To include Consultation

DELIVERY INFORMATION

CLIN DELIVERY DATE QUANTITY SHIP TO ADDRESS DODAAC / CAGE

0001 POP 12-SEP-2022 TO

11-SEP-2027

N/A USARIEM

US Army Research Institute of Environmental Medicine 10 General Greene Avenue, BLDG 42

Natick MA 01760

W561UG

0002 POP 12-SEP-2022 TO

N/A (SAME AS PREVIOUS

LOCATION)

0003 POP 12-SEP-2022 TO

N/A (SAME AS PREVIOUS

LOCATION)

0004 POP 12-SEP-2022 TO N/A (SAME AS PREVIOUS W561UG

11-SEP-2027 LOCATION)

0005 POP 12-SEP-2022 TO

N/A (SAME AS PREVIOUS

LOCATION)

0006 POP 12-SEP-2022 TO

N/A (SAME AS PREVIOUS

LOCATION)

0007 POP 12-SEP-2022 TO

N/A (SAME AS PREVIOUS

LOCATION)

0008 POP 12-SEP-2022 TO

N/A (SAME AS PREVIOUS

LOCATION)

0009 POP 12-SEP-2022 TO

N/A (SAME AS PREVIOUS

LOCATION)

CLAUSES INCORPORATED BY FULL TEXT

52.216-18 ORDERING. (AUG 2020)

(a) Any supplies and services to be furnished under this contract shall be ordered by issuance of delivery orders or task orders by the individuals or activities designated in the Schedule. Such orders may be issued from Sept 2021 through Aug 2026.

(b) All delivery orders or task orders are subject to the terms and conditions of this contract. In the event of conflict between a delivery order or task order and this contract, the contract shall control.

(c) A delivery order or task order is considered "issued" when--

(1) If sent by mail (includes transmittal by U.S. mail or private delivery service), the Government deposits the order in the mail;

(2) If sent by fax, the Government transmits the order to the Contractor's fax number; or

(3) If sent electronically, the Government either--

(i) Posts a copy of the delivery order or task order to a Government document access system, and notice is sent to the Contractor; or

(ii) Distributes the delivery order or task order via email to the Contractor's email address.

(d) Orders may be issued by methods other than those enumerated in this clause only if authorized in the contract.

(End of clause)

52.216-19 ORDER LIMITATIONS (OCT 1995)

(a) Minimum order. When the Government requires supplies or services covered by this contract in an amount of less than $1,000, the Government is not obligated to purchase, nor is the Contractor obligated to furnish, those supplies or services under the contract.

(b) Maximum order. The Contractor is not obligated to honor -

(1) Any order for a single item in excess of $850,000.00

(2) Any order for a combination of items in excess of $850,000.00 or

(3) A series of orders from the same ordering office within 5 days that together call for quantities exceeding the limitation in paragraph (b) (1) or (2) of this section.

(c) If this is a requirements contract (i.e., includes the Requirements clause at subsection 52.216-21 of the Federal Acquisition Regulation (FAR)), the Government is not required to order a part of any one requirement from the Contractor if that requirement exceeds the maximum-order limitations in paragraph (b) of this section.

(d) Notwithstanding paragraphs (b) and (c) of this section, the Contractor shall honor any order exceeding the maximum order limitations in paragraph (b), unless that order (or orders) is returned to the ordering office within 10 days after issuance, with written notice stating the Contractor's intent not to ship the item (or items) called for and the reasons. Upon receiving this notice, the Government may acquire the supplies or services from another source.

52.216-22 INDEFINITE QUANTITY. (OCT 1995)

(a) This is an indefinite-quantity contract for the supplies or services specified, and effective for the period stated, in the Schedule. The quantities of supplies and services specified in the Schedule are estimates only and are not purchased by this contract.

(b) Delivery or performance shall be made only as authorized by orders issued in accordance with the Ordering clause. The Contractor shall furnish to the Government, when and if ordered, the supplies or services specified in the Schedule up to and including the quantity designated in the Schedule as the "maximum". The Government shall order at least the quantity of supplies or services designated in the Schedule as the "minimum".

(c) Except for any limitations on quantities in the Order Limitations clause or in the Schedule, there is no limit on the number of orders that may be issued. The Government may issue orders requiring delivery to multiple destinations or performance at multiple locations.

(d) Any order issued during the effective period of this contract and not completed within that period shall be completed by the Contractor within the time specified in the order. The contract shall govern the Contractor's and Government's rights and obligations with respect to that order to the same extent as if the order were completed during the contract's effective period; provided, that the Contractor shall not be required to make any deliveries under this contract after delivery date specified on an order issued prior to the expiration of contract to include all options exercised.

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