Thermofisher_ SOW.pdf

STATEMENT OF WORK

2/5/2024

1) BACKGROUND INFORMATION

The Electron Microscopy (EM) Unit of the Research Technologies Branch (RTB) provides state-of-the-art technologies to support the ultrastructural imaging needs of National Institute of Allergy and Infectious (NIAID) scientists both in the Bethesda, Maryland, area and at the Rocky Mountain Laboratories (RML) in Hamilton, Montana. The facility provides sample preparation and analysis ranging from basic to high resolution structural studies to immuno-localization of selected antigens for a wide array of specimens. A variety of methods, protocols, and equipment are employed to accommodate different preparative and imaging needs. Real-time viewing of samples by video image-sharing is available to NIAID users, enabling scientists at distant locations the ability to view samples simultaneously with microscopy staff. In order to continue to provide for the needs of NIAID researchers, the RTB must continue to upgrade, expand and maintain its instrumentation.

RTB requires service agreements for two FEI Company (FEI) Titan Krios 300kV High-resolution cryo TEMs and one Helios G4 FIB-SEM. The Krios microscopes are state-of-the-art microscopes that is used to solve structures of wide variety of proteins ranging from Prions and HIV spike to various vaccine candidates. The Helios G4 FIB -SEM has allowed NIAID investigators to study pathogen interaction by reconstructing the whole cell. Using the ion beam this microscope allows for removal of very thin layer of biological material to be imaged by the electron beam. These specialized microscopes need the highest level of training to operate and maintain. Since these microscopes operate 24/7 collecting data any down time has adverse effect on the mission of NIAID.

2) SCOPE

The contractor shall perform preventative, remedial maintenance, and repair services to maintain the following equipment to maintain it in optimal operating condition in accordance with the equipment manufacturer’s specifications.

Serial No. Description:

9930413 Krios G4 (4.1)

9930413.03 X-FEG Unit 300 kV

9930413.04 Ceta 16M Camera

300 kV

9930413.12 Phase Plate Solution

9930413.20 Falcon 4 300 kV

D3197 TEM FEG Titan D3197.8 Falcon-3EC D3197.6 Phase Plate Titan D3197.32 X-FEG unit 300 kV

D3197.33 Orius SC200D 300Kv Cam.

Helios G4 UX

3) CONTRACTOR REQUIREMENTS

The contractor shall provide all service reports, materials, parts, test equipment, transportation, labor, and all related services necessary to service the FEI equipment listed above at RML.

The contractor shall provide:

a) Full coverage for OEM replacement parts, labor, and travel. Coverage includes all fees associated with repairs (labor and replacement parts) for any service or repairs performed.

b) Priority scheduling and onsite response for all repairs during the period of performance.

Priority is defined as giving priority scheduling equal to a direct contract and guaranteeing the equivalent manufacturer’s priority onsite response. If you are a third-party service provider, the priority scheduling and/or response time, must be listed on your quote.

c) OEM Trained Certified Technician must be available during normal business hours. If you are a third party, documentation of OEM trained technicians is required with your quote.

d) One (1) Preventive Maintenance Inspections to be performed during a twelve-month period

e) 48-hour priority response time for onsite applications support (troubleshooting and repairs)

f) 48-hour priority response time for all emergency repairs and all on site visits

g) Instrument control software and hardware proprietary updates (can occur during scheduled preventative maintenance visits, unless critical for operation of instrument) software and firmware updates upon request, and in conjunction with a scheduled Preventive Maintenance or Corrective Maintenance visit, including software revisions.

Provide End User License Agreement (EULA) if applicable with your quote.

h) Unlimited service visits during normal business days hours, excluding Federal holidays

i) Unlimited telephone support for instruments and applications and Remote Technical

Support during business hours

4) CONTRACTOR SUPPLIED MATERIALS

The Contractor shall provide all necessary parts and equipment necessary to perform remedial repair and planned maintenance of the above equipment.

5) GOVERNMENT FURNISHED MATERIALS

No Government furnished materials are provided under this contract.

6) REPORTING REQUIREMENTS AND DELIVERABLES

Technical support, remedial repair as needed, and one annual planned maintenance (PM). and reporting document of service after PMs and repairs are completed.

7) INSPECTION AND ACCEPTANCE

a) All work will be inspected and approved by Elizabeth Fischer, Microscopy Unit, RTS, RTB, or designee at the completion of any repairs and at the completion of the annual maintenance.

b) All work will be completed in accordance with industry standards by FEI certified technicians.