Statement of Work PROCISE Protein Sequencers.pdf

STATEMENT OF WORK

1) BACKGROUND INFORMATION

The Research Technologies Branch (RTB), Protein Chemistry Section (PCS) enables intramural National Institute of Allergy and Infectious Diseases (NIAID) investigators to use state-of-the-art applications in mass spectrometry, bioinformatics, peptide synthesis and analysis, and protein sequencing in their research programs. Peptide synthesis and analysis provides synthetic peptides, peptide-carrier protein conjugates, peptide purification, and quality control analyses. In addition, our staff is available for advice and consultations. In cooperation with protein sequencing and mass spectrometry, extensive support is available for expert analysis and characterization of peptides, proteins, and small bio-molecules. The PROCISE Protein Sequencers in RTB are the only machines capable of determining the amino acid sequence of proteins/peptides in the NIH community. They are necessary to determine whether or not proteins/peptides are correctly made, by unravelling the amino acid residues from one end of a molecule. Many of the projects involve proving that proteins produced from recombinant sources are pure and therefore usable for antibody production or structural studies involving X-ray crystallography. Additionally, many times proteins can become degraded for a number of different reasons and by utilizing the sequencers we can locate the site of degradation or the reason for this breakdown. Therefore, it is imperative to obtain a Service Agreement for the PROCISE Protein Sequencers to maintain instruments in optimal condition.

These instruments are constantly in use daily and if it were put out of action due to lack of maintenance or mechanical failure the ability of the investigators in the Division of Intramural Research (DIR) to conduct their research would severely handicapped. It is for this reason that a Service Agreement is essential.

2) SCOPE

The scope of this acquisition is to provide a service agreement for two (2) PROCISE Protein Sequencers that consist of the following: 1) Sequencer AB Model 494, Serial #9409169J that includes a PE200 UV detector s/n 292N0060802E and AB 140C HPLC pump s/n 19408167 , and 2) Sequencer AB Model 491, Serial #1000000035 that includes a PE200 UV detector s/n 292N4091001 an AB 140D HPLC pump s/n 110000078.

3) CONTRACTOR REQUIREMENTS:

a) The Contractor shall provide the following service coverage:

• Parts (excluding consumables and reagents), labor and travel for remedial repair during the twelve-month period,

• One (1) Preventive Maintenance (PM) visit per instrument during the twelve-month period,

• Guaranteed priority response time of two (2) business days to schedule repair/service (Monday through Friday, 9:00am to 5:00pm eastern time),

• Software service in accordance with the manufacturer’s latest established service procedures, to include telephone access to technical support for use of program software and troubleshooting of the operating systems,

• Advance notice of installation of all software updates, including regular updates and defective software revisions, and

• Telephone and email access to application technical support during normal business hours (Monday through Friday, 9:00am to 5:00pm eastern time).

4) CONTRACTOR SUPPLIED MATERIALS

The Contractor shall provide all necessary parts and equipment necessary to perform remedial repair and planned maintenance of the above equipment.

5) GOVERNMENT FURNISHED MATERIALS

No Government furnished materials are provided under this contract.

6) REPORTING REQUIREMENTS AND DELIVERABLES

The Contractor shall provide a detailed report of all the steps performed during the annual preventative maintenance and service repair.

7) PERIOD OF PERFORMANCE

The period of performance is July 24, 2020 – July 23, 2021.

8) INSPECTION AND ACCEPTANCE

a) All work will be inspected and approve by RTB, PCS representative at the completion of any repairs and at the completion of the annual maintenance.

b) All work will be completed in accordance with industry standards.