Statement of Requirements.pdf

STATEMENT OF REQUIREMENTS

Liquid Chromatography System

I. BACKGROUND INFORMATION

The Surface and Trace Chemical Analysis Group (STCAG) of the Materials Measurement Science Division (MMSD) of the Materials Measurement Laboratory (MML) has significant research efforts in the fields of forensic science and homeland security. A major focus of these efforts surrounds development, evaluation, and quantification of standard test materials (TMs) for a suite of trace detection technologies. Another is the quantification of trace level drug residues in operational environments. STCAG requires a liquid chromatography system to replace an existing system coupled to a Thermo Fisher Scientific TSQ Quantis-Plus mass spectrometer. An upgraded liquid chromatography system will enable the group to continue research with trace level identification and quantification of inorganic and organic compounds critical to trace contraband detection and forensic science programs.

II. REQUIREMENTS

The Contractor shall deliver a liquid chromatography system and all necessary parts to replace an existing Thermo Fisher Ultimate3000 system connected to a Thermo Fisher TSQ Quantis-Plus. The requirements for a Vanquish Flex system are listed below.

III. SPECIFICATIONS

Compatibility with Existing Technologies

• Must be fully interoperable with a Thermo Fisher TSQ Quantis-Plus mass spectrometer.

Liquid Chromatography System

• Must include a binary pump that:

o Is capable of flow rates from 0.001 mL/min to 8.0 mL/min o Has an operating pressure range of 20 bar to over 1000 bar o Has a flow accuracy of at least ±0.5 % o Has a proportioning precision of at least 0.25 % o Has a 150 µL static mixer o Has leak detection and excess pressure monitoring capabilities o Has a two-dimensional footprint which does not exceed 18 in. by 26 in.

• Must include a split sampler autosampler that:

o Include technology to reduce pressure drops during injections o Has an operating pressure range of 20 bar to over 1000 bar o Has a variable injection volume range of at least 0.1 µL to 25 µL o Has an injection volume precision of 0.25 % or lower o Has an injection volume accuracy of ±0.5 % or better o Has less than 0.005 % carryover o Has a temperature programmable sample compartment with a temperature range of at least 5 °C to 40 °C o Has a sample compartment capable of holding at least 50 2.0 mL (12 mm O.D.) vials o Has leak detection capabilities

• Must include a column compartment that:

o Has a temperature range of at least 5 °C to 100 °C o Has a temperature stability of at least ±0.1 °C o Has the ability to hold at least two columns o Is capable of accepting columns up to 250 mm in length o Has an operating pressure range of 20 bar to over 1000 bar o Has leak detection capabilities

• Must include a diode array detector (DAD) that:

o Has a wavelength range of 190 nm to 800 nm o Has a wavelength accuracy of at least ±1 nm o Has a wavelength repeatability of at least ±0.25 nm o Has a pixel resolution of at least 1.0 nm o Has a settable slit width o Has internal calibration capabilities o Has better than 5 % linearity o Can monitor up to 10 channels and a 3D field o Has leak detection capabilities o Has a two-dimensional footprint which does not exceed 18 in. by 26 in.

o Has a 10 mm (path length), 13 µL (volume) flow cell capable of handling pressures out to 1000 bar

• Must include a second diverter valve that enables a sample to be injected directly into the mass spectrometer or sent through the column without require manual switching of tubing.

• The contractor shall provide an operations and maintenance manual stating the manufacturer’s operating standards, and directions on system operation, maintenance and troubleshooting.

Software

• System must be capable of being controlled by Chromeleon® software, version 7.3 or higher and allow for complete software integration with the ThermoFisher TSQ Quantis-Plus mass spectrometer.

Warranty

• The Contractor shall include at least a one (1) year warranty on the liquid chromatography system.

IV. DELIVERY

Delivery of the instrument shall occur within 60 calendar days of award to Building 217 room C104.

Delivery shall take place during normal business hours between 8:30am to 5:00pm Eastern Time, Monday through Friday, except Federal Holidays.

V. INSTALLATION

The Contractor shall install the instrument in Building 217 room C104 at NIST Gaithersburg, MD within 30 days of delivery. Installation shall include, at minimum, uncrating/unpacking of all equipment, set-up and hook-up of all equipment, start-up demonstration of specifications, and removal of all trash. Instrument will operate to manufacturers specifications upon installation.

Installation will take place during business hours of 8:30 am to 5:30 pm Eastern Time, Monday through Friday, except Federal Holidays, and will be coordinated with the Contracting Officers Representative (COR).

VI. TRAINING

The contractor shall provide training within 30 days of installation for up to three (3) NIST personnel with instruction on proper use, troubleshooting and basic system maintenance.

VII. PLACE OF PERFORMANCE

The Contractor shall accomplish all services at NIST, Gaithersburg, Maryland. Normal duty hours are Monday through Friday, 8:30 a.m. to 5:00 p.m. with the exception of Federal holidays. Work will be coordinated with the COR.

VIII. PERIOD OF PERFORMANCE

Delivery date is within 60 days of award. Anticipated dates for base and options years for initial and extended warranty are as follows:

Option Year I: FY25 to FY26 – 12 months from the end of Manufacturer’s Warranty;

Option Year II: FY26 to FY27 – 12 months from the expiration of the option year I;

Option Year III: FY27 to FY28 – 12 months from the expiration of option year II;

Option Year IV: FY29 t0 FY30 – 12 months from the expiration of option year III

IX. DELIVERABLES

Description Quantit y Due Date Delivery of instrument One (1) Within 60 days of award

Operations and maintenance manual for the accessories (electronic copies) One (1) Within 60 days of award

Installation of the Instrument One (1) Within 30 days after delivery of the instrument

Training for up to 3 people One (1) Within 30 days after installation of the instrument.

X. OPTIONAL SERVICE & MAINTENANCE

Preventative Maintenance

• The Contractor shall include a service and maintenance agreement for up to four (4) years to include, at a minimum, cleaning of the ionization source and ion optics, mass calibration, and detector calibration and verification.

• The service and maintenance agreement shall include the following:

o One routine and preventative maintenance visit per year to ensure long-term performance and reliability of the instrument.

o Preventative Maintenance visits will be coordinated at least 15 days in advance with the Contracting Officers Representative (COR) o Dispatch of a technician for emergency service within 48 hours when the instrument becomes inoperable or fails to perform to specifications due to a failure in the instrument.

o Replacement of defective parts with parts approved for use by the Original Equipment Manufacturer.

XI. SYSTEM ENHANCEMENTS

System Enhancements The Contractor shall be responsible for contacting and notifying the COR of all software updates released not later than 60 days after any such update is released.

If Contractor installation is necessary to ensure proper performance, prior to completion of the installation, the Contractor shall test the equipment, review the instrument’s performance, and take whatever steps necessary to ensure each instrument is function in accordance with the manufacturer’s specifications.

Service Tickets The Contractor shall submit a service ticket prior to departure from NIST on any given service call for maintenance or repairs. The service ticket shall include the following:

a. Date and time of arrival to NIST.

b. Description of service performed.

c. Name and quantity of any parts that were repaired.

d. Name and quantity of any parts that were replaced.

e. Date and time of departure from NIST.

f. Diagnostic test results or narrative summary demonstrating that the instrument and/or accessories are meeting the performance standards.

g. Any comments or recommendations.

h. Signature of Contractor’s service person

i. Signature block for accepting services rendered.

XII. ACCEPTANCE CRITERIA

Formal acceptance of the system will be given at the time the Contractor demonstrates all performance standards have been met.

XIII. GENERAL INFORMATION

Safety: The Contractor employee shall be responsible for knowing and complying with NIST installation safety prevention regulations. Such regulations include, but are not limited to, general safety, fire prevention, and waste disposal.

Security: NIST is a restricted campus. An identification badge is required for access for entry into buildings and also is shown to the armed Security Police when entering the campus.

Identification Badges: Contractor employees shall comply with NIST identification and access requirements. Each Contractor employee shall wear a visible identification badge provided by the NIST Security Office.

Vehicle Registration: All Contractor employees must register their vehicles with the NIST Security Office to gain access to the campus. A valid driver’s license, Government-furnished civilian ID, proof of insurance and current registration must be presented to the NIST Security Office, at which time a NIST vehicle pass will be issued. The pass shall be displayed on the vehicle’s rear view mirror in accordance with instructions.