SSN - Service Agreement.pdf

SOURCES SOUGHT NOTICE

1. Solicitation Number: 75N95025Q00217

2. Title: Service agreement for four (4x) Access Systems and twelve (12x)

Echo Acoustic Liquid Handlers, and one (1x) Biomek i7 Hybrid System

3. Classification Code: 6640 – Instruments and Laboratory Equipment

4. NAICS Code: 334516 – Analytical Laboratory Instrument Manufacturing

5. Description:

This is NOT a solicitation for proposals, proposal of abstracts or quotations. The purpose of this notice is to obtain information regarding: (1) the availability and capability of qualified small business sources; (2) whether they are small businesses (e.g., 8(a), Veteran-owned small businesses, service-disabled Veteran-owned small businesses, HUBZone small businesses, small disadvantaged businesses, and women-owned small businesses); and (3) their size classification relative to the North American Industry

Classification System (NAICS) code for the proposed acquisition. Your response to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set-aside is possible.

This notice is issued to help determine the availability of qualified companies technically capable of meeting the Government requirement and to determine the method of acquisition. It is not construed as a commitment by the Government to issue a solicitation or ultimately award a contract. Responses will not be considered as proposals or quotes. No award will be made as a result of this notice. The Government will NOT be responsible for any costs incurred by the respondents to this notice. This notice is strictly for market research and information purposes only. Furthermore, it should be noted that any future solicitations that may be issued as a result of this notice, or in response to this requirement, may be issued using a different solicitation number from the one identified above.

Background: The Neuroimaging Research Branch (NRB) previously identified that change in brain regions using the non-invasive imaging technique called functional magnetic resonance imaging (fMRI) associated with addiction vulnerability. This vulnerability can be measured by drug-taking behavior despite foot shock in rats. Early social experiences, including peer interactions, are critical for brain development and behavioral regulation. Disruptions in these experiences have been linked to increased risk of substance use disorders. However, it is unclear how social experiences affect vulnerability to substance used disorders.

To shed light on this issue, the proposed self-administration system will allow researchers to evaluate social interaction behavior, drug self-administration and compulsive drug-taking behaviors. These behavioral assessments are essential for understanding how social experiences modulate brain-behavior relationships involved in substance used disorders. This finding is expected to inform future prevention strategies and supports the development of more effective therapeutic interventions for substance use disorders.

Purpose and Objectives: The purpose of this acquisition is to purchase an additional self-administration system, which is used to train rats to self-administrator compounds such as methamphetamine or heroin, and test the social interaction behavior.

Project requirements: The Contractor shall provide one (1) self-administration system with the following specifications:

• The required self-administration system must meet the following essential physical, functional and compatibility requirement to support the Government’s research objective in modeling substance used disorder in rodents:

Physical requirements: 1). The required system must support operant conditioning paradigms for both drug self-administration and social interaction tasks with a single behavioral chamber. 2). All chambers and components mush be constructed from animal-safe durable materials suitable for repeated cleaning and sterilization. 3). The chamber design must integrate the lever, cue lights, social access doors and intravenous drug infusion, as required for social and drug self-administration paradigms. 4) The system should include a shock grid and shocker module to deliver electric foot shock to simulate aversive consequences in behavioral tasks.

Functional requirements: 1) The system should support precise and programmable control over both drug delivery and social interaction tasks (e.g., access control to conspecific chambers) within operant conditioning chamber. 2) The system should control programmable foot shock in the range of 0.05-0.8 mA as a negative consequence to model compulsive drug tasking behavior.

Performance and compatibility requirements: 1) The system should be fully compatible with existing Med-PC IV software to enable programming to control all experimental modules. 2) The system should be fully compatible the existing behavioral equipment currently in use including 16 sets of Med associates self-administration chambers and control hardware to ensure the data continuity and consistency across studies.

Warranty: one-year warranty

Capability statement /information sought.

Companies that believe they possess the capabilities to provide the required products or services should submit documentation of their ability to meet each of the project requirements to the Contracting Officer. The capability statement must specifically address each of the project requirements separately. Additionally, the capability statement should include 1) the total number of employees, 2) the professional qualifications of personnel as it relates to the requirements outlined, 3) any contractor

GSA Schedule contracts and/or other government-wide acquisition contracts (GWACs) by which all of the requirements may be met, if applicable, and 4) any other information considered relevant to this program. Capability statements must also include the

Company Name, Unique Entity ID from SAM.gov, Physical Address, and Point of

Contact Information. The response must include the respondents’ technical and administrative points of contact, including names, titles, addresses, telephone and fax numbers, and e-mail addresses.

Interested companies are required to identify their type of business, applicable North

American Industry Classification System (NAICS) Code, and size standards in accordance with the Small Business Administration. The government requests that no proprietary or confidential business data be submitted in a response to this notice.

However, responses that indicate the information therein is proprietary will be properly safeguarded for Government use only. Capability statements must include the name and telephone number of a point of contact having authority and knowledge to discuss responses with Government representatives. Capability statements in response to this market survey that do not provide sufficient information for evaluation will be considered non-responsive. When submitting this information, please reference the solicitation notice number.

One (1) copy of the response is required and must be in Microsoft Word or Adobe PDF format using 11-point or 12-point font, 8-1/2” x 11” paper size, with 1” top, bottom, left and right margins, and with single or double spacing.

The information submitted must be in and outline format that addresses each of the elements of the project requirement and in the capability statement /information sought paragraphs stated herein. A cover page and an executive summary may be included but is not required.

The response is limited to ten (10) page limit. The 10-page limit does not include the cover page, executive summary, or references, if requested.

All responses to this notice must be submitted electronically to the Contract Specialist and Contracting Officer. Facsimile responses are NOT accepted.

The response must be submitted to Scott Duernberger, Contract Specialist at e-mail address scott.duernberger@nih.gov.

The response must be received on or before 3:00pm Eastern Time July 17, 2025.

“Disclaimer and Important Notes: This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The

Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the

Government to determine the organization’s qualifications to perform the work.

Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a pre-solicitation synopsis and solicitation may be published in www.sam.gov. However, responses to this notice will not be considered adequate responses to a solicitation.

Confidentiality: No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s).”