SSN BNOE 75N91024SS6826350.pdf

75N91024SS6826350 Page 1 of 5

GENERAL INFORMATION/CLASSIFICATION

Title: Brand Name or Equal: Scintica Prospect T1 High Frequency Ultrasound

Imaging System Notice Type: Sources Sought Solicitation Number: 75N91024SS6826350 Posted Date: 02/12/2024 Response Date: 02/19/2024 PSC Code: 6640 – Laboratory Equipment and Supplies NAICS Code: 423450 – Medical, Dental, and Hospital Equipment and Supplies

Merchant Wholesalers

ISSUED BY:

National Institutes of Health (NIH), National Cancer Institute (NCI), Office of Acquisitions (OA)

DESCRIPTION:

This is a Sources Sought Notice (SSN) and is for information and planning purposes only. This notice shall not be construed as a solicitation or as an obligation on the part of the National Cancer Institute (NCI). The purpose of this SSN is to identify qualified business concerns, especially small businesses, that are interested in and capable of performing the work described herein, The NCI does not intend to award a contract based on responses received nor otherwise pay for the preparation of any information submitted. Responses to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set-aside is possible. The requirement’s suggested North American Industry Classification System (NAICS) code is 423450 – Medical, Dental, and Hospital Equipment and Supplies Merchant Wholesalers with a size standard of 500 Employees.

THERE IS NO SOLICITATION AVAILABLE AT THIS TIME. However, should such a requirement materialize, no basis for claims against NCI shall arise because of a response to this SSN or the NCI’s use of such information furnished in response to this notice.

RESPONSE INSTRUCTIONS:

Responses to this notice shall be submitted via email to the Contracting Officer, Miguel Diaz, at miguel.diaz@nih.gov no later than 12:00 P.M. EST on Monday, February 19, 2023 (02/19/2024).

All information furnished must be in writing and must contain enough detail to allow the NCI to determine the respondents’ ability to meet the requirements described herein. A response should not exceed 10 single-sided pages including all attachments, charts, etc. (single space, 12-point font minimum) that clearly responds to the below questions. All proprietary information should be marked as such. Please reference notice number 75N91024SS6826350 for all correspondence.

Requested Information: Please provide the following information in your company’s response:

1. Company Name

2. Point of Contact (POC) (including telephone and email address)

3. Company’s System for Award Management Unique Entity Identifier (UEI)

4. Socio-economic status (8(a), SDVOSB, VOSB, Woman-Owned, Other… etc.).

5. Information on any currently held government contracts to include:

a. Contract Number

b. Type of Contract

c. Contracting Agency (GSA, SEWP, etc.)

d. If you hold a current GSA schedule contract, specify which SINs are best suited for providing the services/items specified in the SOW.

6. Provide product information such as brochures, manuals, etc. to demonstrate that the proposed equipment is:

75N91024SS6826350 Page 2 of 5

a. equal to or greater than the minimum required features/characteristics listed in Section 1.0

SPECIAL ORDER REQUIREMENTS.

b. the brand name equipment listed in Section 2.0 BRAND NAME PRODUCTS.

7. Provide any available pricing information.

8. Provide information pertaining to the origin of the equipment, and where it’s manufactured.

This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use the information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization’s capability. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a synopsis and solicitation may be published. However, responses to this notice will not be considered an adequate response to a solicitation(s).

TITLE

Scintica Prospect T1 High Frequency Ultrasound Imaging System – Brand Name or Equal

BACKGROUND

The Pediatric Solid Tumor and Immunotherapy Section, Pediatric Oncology Branch (POB), Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), develops new immunotherapies for patients with neuroblastoma by tracking tumor growth in mice. High frequency ultrasound imaging will allow POB investigators to measure tumor sizes without harming the animals and ultimately help to assess tumor response to different therapies.

TYPE OF ORDER

This is a Firm Fixed-Price Purchase Order.

1.0 SPECIAL ORDER REQUIREMENTS

1.1 PRODUCT FEATURES/SALIENT CHARACTERISTICS

The following minimum product features/characteristics are required:

1. Footprint: The entire system must have a compact design and fit into biosafety cabinets to allow working with immunocompromised animals.

2. Portability: Portability of the system is required as it will be utilized in multiple locations within the NCI facilities.

3. Type of experiments: The system shall be specifically designed for in vivo preclinical high frequency imaging of small animals (mice).

a. The high frequency ultrasound probe must be designed specifically for small animal imaging (40 MHz / broadband 20-50 MHz).

b. The device must have an integrated anesthesia cone to keep mice properly anesthetized during imaging.

c. The system must monitor mice vitals (body temperature, respiration, ECG, heart rate) during imaging, with the option to export ECG and respiratory data.

d. The animal bed shall be:

i. specifically designed for mice (approximately 17 cm x 14 cm).

ii. heated to help maintain body temperature during ultrasound procedure.

iii. tiltable in all directions to achieve required imaging windows.

4. Performance characteristics:

75N91024SS6826350 Page 3 of 5

a. High resolution (up to 30 µm) to be able to detect tumors that are too small to be detected by other means such as physical palpation.

b. Up to 190 frames per second (fps) frame rate for high quality measurements.

c. Able to track and record tumor size/progression over time.

d. The system must have multiple scanning modes. This shall include contrast, pulse-wave, and the capability to measure tumors in one dimension, (1D), 2 dimensions (2D) and three dimensions (3D) as follows:

i. Contrast ultrasound capabilities (linear, nonlinear) to assess vascularity.

ii. Pulsed-wave Doppler mode to measure blood flow velocity profiles over time.

iii. 1D mode (M mode) for measuring cardiac function and movement of blood vessel walls.

iv. 2D mode (B mode) to collect images in real time for exploration and to observe motion.

v. The system shall allow real-time overlay of B-mode images when blood flow is detected.

vi. The system shall include a 3D motor for controlling the ultrasound probe at 0.05 mm scan intervals.

5. User-friendliness:

a. The system shall have an ergonomic design to allow easy positioning and scanning of the animals.

b. The system shall have a touchscreen to intuitively control the workflow.

c. The injection mount shall be attached to the probe to keep the needle aligned to the imaging plane.

d. Probe and needle shall be adjustable by the user for injections as needed, whilst being mounted and connected.

6. Image acquisition and analysis software shall allow:

a. Immediate ‘online’ (on the instrument) and in-depth ‘offline’ (through separate software) image analysis.

b. Selection of the distance and the step size the 3D motor will travel.

c. Calculation of diastolic function in the heart.

d. Vascular function in vessels, including small saphenous arteries.

e. Measurements of tissue velocity profiles over time.

f. Reconstruction of imaging slices into 3D images.

g. Movement through the acquired 3D image.

h. Visualization of a 3D surface.

i. Volume measurements.

7. Upgrade capabilities: the system shall have the capacity to be upgraded to accommodate for additional needs as the projects expand over time. These upgrades may include the addition of shear wave imaging capabilities and/or the addition of a sonoporation probe.

75N91024SS6826350 Page 4 of 5

2.0 BRAND NAME PRODUCTS.

2.1 The following Brand Name products have been identified to fulfill these requirements:

Item Product Description Product No. Qty Amount

Prospect T1 High Frequency Ultrasound Imaging System For Mice; includes:

• 15" tablet ultrasound system controller

• Imaging software

• Included modes: B-mode, M-mode, Doppler

(Color and Power) mode, PW Doppler, Tissue Doppler, Analog Doppler, and Contrast mode.

• Scanning platform with mouse table

• 40 MHz probe designed for mouse imaging

• 1-year warranty

SSPT1-

SysM40 1

3D Imaging Package; includes:

• 3D motor

• Analysis software

SSPT1-3D 1

Prospect T1 Integrated Anesthesia System (5) with Air Pump (mouse); includes:

• Easy-fill isofluorane vaporizer with 5 individually controlled channels to provide anesthesia to the knock-down chamber (included) and to the imaging system

• Active gas exhaust scavenging system with 6 charcoal canisters, weight monitoring device and anesthesia air pump

SSPT1-

Ansth(5) Pump -mouse

(RWD)

4 Offline Analysis Software (one seat) SSPT1- Offline 1

5 On-Site Customer Training (three days) n/a 1 6 Shipping n/a 1

Total:

DELIVERY / INSTALLATION

Delivery shall be within ninety (90) calendar days of the purchase order award. All shipping/handling (including FOB) and delivery/installation fees shall be included in the quote. Upon delivery, the Contractor shall notify the respective NCI Technical Point of Contact (TPOC) to schedule installation dates and times. Installation shall occur within one (1) business day of delivery and shall be performed by, or under the direct supervision of, an Original Equipment Manufacturer (OEM) certified technician.

Equipment shall be delivered to and installed at the following address:

Bldg. 10, Room 1-5832 10 Center Drive Bethesda, MD 20892

The NCI Technical Point of Contact (TPOC) will be listed in the purchase order.

TRAINING

The Contractor shall provide one (1), three (3) day training session for up to four (4) NCI staff at the location of delivery. Training shall take place within seven (7) days of equipment installation and shall be

75N91024SS6826350 Page 5 of 5 facilitated by a factory-trained product specialist. Training shall include an overview of setup approaches, maintaining instrument settings, establishing operational voltages, and software usage for custom instrument configurations, as well as a demonstration of the performance. All training expenses, including materials and/or travel expenses, shall be included in the quoted price.

TECHNICAL POINT OF CONTACT

The Technical Point of Contact (TPOC) is responsible for inspection and acceptance of all work in relation to this requirement and will serve as the Governments primary point of contact throughout the duration of the requirement. All efforts must be coordinated with this individual.

Note: The TPOC has limited authority as defined within this Statement of Work. They do not have the authority to commit or obligate Government funds or make changes to the terms and conditions of the purchase order. As such, any changes to the purchase order must be performed by a warranted Government Contracting Officer with appropriate delegated authority to do so.

INSPECTION AND ACCEPTANCE

Pursuant to FAR clause 52.212-4, all work described in the SOW to be delivered under this purchase order is subject to final inspection and acceptance by an authorized representative of the Government. The authorized representative of the Government is the NCI Technical Point of Contact (TPOC) who is responsible for inspection and acceptance of all services, materials, or supplies to be provided by the Contractor.

PAYMENT

Payment shall be made in full after the successful delivery, installation, training, and acceptance of equipment by the NCI Technical Point of Contact (TPOC).