Specifications.docx

SPECIFICATIONS

Gas Chromatograph Single Quad Mass Spectrometer with Head space autosampler and thermal desorption unit (TDU)

I. BACKGROUND INFORMATION

The National Institute of Standards and Technology’s Chemical Sciences Division serves as the Nation's reference laboratory for chemical measurements and standards to enhance U.S. industry's productivity and competitiveness, assure equity in trade, and provide quality assurance for chemical measurements used for assessing and improving public health, safety, and the environment. The Chemical Sciences Division is responsible for development and characterization of Standard Reference Materials (SRMs) to enhance chemical measurement comparability within the U.S. and to provide a basis for measurement comparability with other nations.

II. OBJECTIVE/PURPOSE

The Contractor shall provide one (1) Agilent 8890/5977B Gas Chromatograph - Mass Selective Detector (GC-MSD) inclusive of Agilent part numbers (G3540A, G7078BA, G3397B, G4513A, G4557A, and G4514A) with headspace autosampler (G4557A), a Markes thermal desorber units and oil free scroll pump to be used for the low-end exposure science, flame retardant (PFOA and PFOS), plastic marine debris, per and poly-fluorinated alkyl substances, and persistent organic contaminants.

III. REQUIREMENTS

The instrument must reproducibly generate high-quality MS data, and give reproducible quantitative results and data compared to other GC/MS instruments with use of Agilent Mass hunter software and Data.

The equipment is specifically designed for single quad mass spectrometric measurements, that consists of benchtop instruments with integrated instrument control and data analysis software. The inclusion of a benchtop headspace autosampler and a benchtop thermo desorber are required. The mass spectrometer instrument and software must be capable of utilizing, with full software seamless integration and automation, existing GC/MS equipment specifically the Agilent 5973/7000 and Mass Hunter software.

IV. SPECIFIC REQUIREMENTS

The Contractor shall provide a GCMS instrument, and software for complete instrument system control and data analysis capabilities, meeting the salient characteristics as defined below.

GC features and capabilities:

· The GC must have a cool on column inlet and a Multimode inlet for injections with electronic pressure control and liquid nitrogen cooling inlet.

· The GC must be capable of full electronic pressure and flow control of all gas flows.

· The MSD mainframe with oil free scroll pump must be capable of electron ionization and chemical ionization and must include Extractor (inert) EI and CI sources and Ion Gauge.

Mass Spec features and capabilities:

· The MSD must be capable of full scan and selective ion monitoring (SIM) and must be able to collect SIM and full scan data simultaneously.

· The MSD must be capable of generating classical Electron Ion (EI) spectra, without any contamination by extraneous effects that might skew the naturally occurring abundances, that can be compared against commercial libraries.

· An autoinjector for the GC/MSD system must be included with all mounting posts, solvent wash bottles/vials and 10 μL injector syringes.

· A sample tray supporting the autoinjector and includes GC mounting brackets and 3 removable trays each holding 50 sample vials.

· The Contractor shall provide a headspace autosampler that can handle up to 100 vials and 12 vial heating.

Computer and Software control features:

· The Contractor shall provide the data acquisition, processing software, and systems used to control the GC/MSD and autosamplers using a supplied computer running Microsoft Windows 10 Enterprise or greater.

· The Contractor shall provide an Agilent MassHunter Software system (version 7.0 or later) that is compatible with the laboratory’s current standard for data management, processing, and quality control.

· The Contractor must ensure that Multiple analytical instrument methods can run in the same sequence.

· The Contractor shall ensure that the GS-MS software can automatically acquire MSD data, calibrate, and quantify target compounds, perform library searches of spectra obtained for target and non-target compounds, and export the data to NISTs data processing software.

· Must have instrument interface and control via LAN (TCP/IP protocol) to the data acquisition and data processing software and systems.

Software Upgrades:

· Install, or if NIST technical personnel can install the upgrades without compromising system performance make available for installation, all software upgrades for the purposes of instrument optimization not later than 60 days after any such upgrade is released.

· If Contractor installation is necessary to ensure proper performance, prior to completion of the installation, the Contractor shall test the equipment, review the equipment’s performance, and take whatever steps are necessary to ensure the equipment is functioning in accordance with the manufacturers’ specifications.

Instrument Description Specification

b. Must have a 7-inch capacitive touch screen interface to provide access to instrument status, configuration, and flow path information as well as additional tabs to provide quick access to key functions such as editing method parameters, diagnostics, maintenance, logs and help screens.

c. Must have a Browser interface that can be used on tablets or a PC and allows the user to view setup information, troubleshoot problems, check for leaks, pause and start runs, and manage method development. Must include three USB ports.

d. Injection Ports:

i. Must include one Cool-On Column Injector

ii. Must include one Multi Mode Injector which allows hot or cold split/splitless, pulsed split/splitless, solvent vent, or direct injections. The solvent elimination mode allows for Large Volume Injection applications.

b. Shall use a robotic arm with active gripper and sensor technology to ensure positive sample transfer to autoinjector module.

c. Must have a 150-sample tray that holds 2.0 mL autosampler vials

d. Must run samples unattended with at least 3 solvent wash vials Installed on a split/splitless inlet.

b. Must include both an InertPlus EI source as well as a Chemical Ionization (CI) source

i. Must be capable of both electron impact and chemical ionization

c. 1 picogram of octafluoronaphthalene injected in 1uL iso-octane solvent onto a 30m x 0.25mm x 0.25um HP-5MS ultra inert column with data acquired at 2.9 scans/second over the mass range 50-300 amu shall yield an RMS signal/noise of at least 1500:1 for the extracted ion signal at mass 272.0, using helium as the carrier gas and a diffusion vacuum system.

d. The EI SIM IDL, using Helium carrier gas with an autosampler performing 8 sequential 1 uL injections of 100 fg/uL OFN standard solution at the nominal 272 u ion must be less than 10 fg.

e. Mass Accuracy must give the following results: 1 uL injection of 100 pg/uL OFN, scanning from 50 to 300 u, will give its monoisotope at m/z 272.987 plus or minus 0.005.

f. The Mass Spectrometer must have an electronic scan rate of 20,000 u/sec.

g. SIM speed must be down to 0.1 msec

h. The instrument must scan from 1.6 to 1050 u

i. Vacuum System must be an air-cooled vacuum system with an oil free Scroll rough pump and a Turbo Molecular vacuum pump. The systems must allow venting of the high vacuum and access to the source volume without requiring column removal.

i. This is critical in ensuring the seamless method transfer and quality assurance between existing Agilent GCMS instrumentation which operates under MassHunter/Chemstation software and the new GCMS.

b. A complete software package for control of the gas chromatograph, mass spectrometer, autosampler, headspace autosampler and thermo disorber is required. In addition, it must include the capability to control autotunes, data acquisition, data analysis, method automation, macro programming, reporting, and system management utilities.

b. compatible with other Agilent GCMS’s and GCMSMS onsite

c. Must be able to heat samples to 300 degrees C.

d. Must be able to be connected to the GC so that both the liquid autosampler and headspace autosampler are able to inject into the same inlet without the need for any change in configuration of the hardware

c. Must be compatible with GCMS software

V. WARRANTY:

The Contractor shall provide, at a minimum, a one (1) year warranty for the system’s non-consumable parts and shall commence upon successful completion of deliverables and a demonstration of salient characteristics inclusive of

· Parts, labor, and travel;

· Software and firmware updates;

· One (1) Preventative Maintenance

· Unlimited, free email and phone support;

· In the event that NIST is unable to resolve a problem, the Contractor shall provide remote support as needed to expedite a solution for NIST;

· Telephone support for the equipment during regular business hours of 8:30AM to 5:00 PM to include response to questions about operating practices, application use, and service issues that can be diagnosed and resolved over the telephone.

· The Contractor shall maintain accurate records of maintenance and repair activities.

VI. DELIVERY:

Delivery shall be FOB Destination to Charleston SC., and shall occur within 60 days of award. However, due to current access restrictions, delivery shall not take place until the Contractor coordinates with the Contracting Officers Representative (COR) and Contracting Officer (CO). Prior to shipment, the Contractor must ensure NISTs campus is open and accepting deliveries. If the restrictions of access to the campus impacts delivery schedules, a modification may be executed by the CO to establish an extended delivery timeframe.

VII. INSTALLATION:

The contractor shall schedule and facilitate installation/set-up at NIST Charleston, SC. Installation shall include, at a minimum, uncrating/unpacking of all equipment, set-up and necessary connections for operation (liquid nitrogen supply lines), hardware and software installation, basic functionality, instrument start-up (no leaks), demonstration of instrument performance with the specifications and removal of any trash. Installation shall take place between 8:30 AM and 5:00 PM Monday through Friday, with the exception of holidays. Installation shall be coordinated with the NIST Contracting Officers Representative (COR. shall occur within 30 days of delivery.

VIII. TRAINING:

One (1) basic user training session for up to six (6) users at NIST Charleston, SC. The training shall provide a basic demonstration of all equipment functions, maintenance, data administration, data acquisition, and troubleshooting. The training may be completed at NIST immediately after installation/set-up and on-site measurements demonstrating that no damage or misalignment issues arose during transportation and installation (as described below) but shall be completed no later than 30 days after delivery

IX. DELIVERABLES

X. ACCEPTANCE CRITERIA

Acceptance of a fully functional instrument, inclusive of components, spares, accessories, consumables, and related hardware shall be delivered, installed, and tested in accordance with the minimum specifications described herein.

COMPLIANCE WITH NIST RULES AND REGULATIONS

While on the NIST campus, the Contractor’s representative(s) shall abide by all NIST rules and regulations. The Contractor shall provide all information necessary for the TPOC to authorize entrance to the NIST campus in accordance with NIST Security Policy and Procedure.