SOW FOR RFQ.pdf

Request for Quotation Number 1333ND24QNB640677

Statement of Work

TITLE: GC-MS System

BACKGROUND

The National Institute of Standards and Technology (NIST), Material Measurement Laboratory (MML), Biomolecular Measurement Division (BMD) in Gaithersburg, Maryland is responsible for the development of chemical databases to accomplish NIST’s mission to carry out collection, compilation, critical evaluation, publication and sale of standard reference data in accordance with Public Law 90-396. 90th Congress, H.R.

6279, July 11, 1968.

The chemical databases provide standard reference data for laboratories, both within NIST and to the worldwide scientific community. The Mass Spectrometry Data Center (MSDC), a component of the BMD, is responsible for the development of the NIST/NIH/EPA Mass Spectral Library and special Mass Spectral Libraries

(hereinafter, the Libraries) (http://www.nist.gov/srd/nist1a.cfm, http://chemdata.nist.gov/dokuwiki/doku.php?id=peptidew:start). This development includes generating and analyzing data obtained by Gas Chromatography-Mass Spectrometry (GC-MS).

OBJECTIVE

The objective of the project is to facilitate the expansion of the NIST/NIH/EPA Mass Spectral Library by adding a GC-MS System to the MSDC’s laboratories.

SCOPE

The Contractor shall provide a GC-MS system meeting the specifications listed below. The Contractor shall install the instrument, demonstrate all required specifications, provide training, and warranty.

BRAND NAME JUSTIFICATION

This is a brand name only requirement.

The Agilent mass spectrometer and its components for sample handling (autosampler) and for separation of components of samples (gas chromatograph) must be controlled through integrated software to enable use of one sample list and one method on one PG. The PC must run on Windows 10 operating system to satisfy NIST lT requirements.

The components for all measurements must be provided in an integrated package by a single vendor. All system components (autosampler, GC, inlet, and mass spectrometer) must be controlled through integrated software to enable use of one sample list and one method on one PC and be compatible with current software and instruments in use in the MSDC. Current systems are Agilent GC-MS instruments liquid inlet, autosampler based devices that run on the Windows 10 operating system.

The heated quadrupole is an important feature to maintain high vacuum and cleanness of the mass spectrometry system. The heating is necessary to remove degradation products of samples and facilitates acquisition of high-quality electron ionization mass spectra. This feature is especially important for the BMD analyzing various chemical and biological samples of synthetic and natural origin at a large scale. Only Agilent mass spectrometry instruments include quadrupole that can be heated up to 200 oC.

SYSTEM REQUIREMENTS

The Contractor shall provide one Agilent brand name GC-MS System, 5977C EI/CI MSD) / 8890B Series GC.

The Contractor shall also provide one Agilent Autosampler consisting of 7693A Autoinjector, 7693 Tray with

150 vial capacity.

Mass Spectrometer

1. Mass analyzer: Single quadrupole

2. Electron ionization (EI) mode and chemical ionization (CI) mode

3. Sensitivity: S/N 1500:1 (EI) with 1 pg Octafluoronaphthalene (OFN), scanning 50-300 u at 272 u ion.

4. Instrument Detection Limit: 10 fg (EI).

5. Scan speed: The scan speed of the instrument must be up to 20,000 u/sec.

6. Mass range: The instrument must scan from 0.6 u – to 1091 u. +/- 10% of this range is acceptable.

7. Ion source temperature: Ion source temperature must have the capability to heat up to 350°C.

8. The heated quadrupole: The quadrupole must be able to be heated up to 200°C.

9. Scan increment (step size): Scanning at the increments of 0.1 u.

10. Tune: The Mass Spectrometer must have standard and optional spectra tuning capabilities. “Standard tune” means a standard response over the entire scan range, and “optional tune” can discriminate low masses and show high mass peaks with greater intensities.

11. Oil free foreline pump.

12. Must provide equivalent spectra for helium and hydrogen carrier gas.

Gas Chromatograph

1. The Gas Chromatograph must offer the capability to install two inlet ports. The system must be delivered with one inlet port.

2. Inlet sealing system must allow for easy liner changes without using tools.

3. The inlet vent trap line must be replaceable.

4. Oven dimensions must be not less than: 27 x 30 x 15 cm and not more than 35 x 35 x 25 cm.

5. Oven operating temperature range (Ambient+5 °C to 450°C).

6. Oven temperature set-point resolution shall be 0.1 °C. +/- 10% of this value is acceptable.

7. Split/splitless capillary inlet shall have the split ratio up to 12,500:1, and maximum temperature 400°C capability.

Autosampler

1. XYZ robotic sample handling with syringe concept.

2. Mounted on the GC-MS System.

3. Injection on either GC inlet or both.

4. Capable of sample preparation during GC analysis of the preceding sample.

5. Must include a solvent wash station.

6. Capable of vial capacity of at least 150 x 2 mL vials.

7. Liquid injection techniques including standard and sandwich using air or solvent.

8. Universal syringe holder capable of holding 1 µL – 1000 µL syringes. Injection volume range of .1 µL –

1000 µL.

9. Software controlling the autosampler must be compatible with, and integrated with, the Agilent

ChemStation software controlling the GC-MS System. The autosampler and the GCMS system must communicate without any conflict. A single software package is preferred.

Computer System and Software

The instrument must include a computer system. The instrument must include a software package that controls the instrument, controls data acquisition, includes data mining tools, and includes processing tools.

The software package must also include a post-acquisition software tool, compatible with the data acquisition and processing software, that aids in compound identification. The software package must calibrate the mass position of the peak and calibrate the MS line shape to increase mass accuracy and spectral accuracy to aid in compound identification.

Safety Features

1. The mass spectrometer shall have an automatic interrupt system. In addition, analyzer temperature zone and operating voltages shall be interlocked with vacuum pump speed to prevent instrument damage due to operation at excess pressure.

2. The Gas Chromatograph must have: (a) a hydrogen safety shutdown system that monitors the hydrogen flow and shuts down the gas flows and heaters if a leak is detected, and (b) an oven explosion protection built into the oven door. The Mass Spectrometer analyzer shall not fragmentize in the event of a hydrogen deflagration.

3. The Gas Chromatograph and Mass Spectrometer must have a United States safety certification by an accredited agency.

DELIVERY

Delivery, installation and training shall be completed not later than March 31, 2025, at Building 221 at the

National Institute of Standards and Technology (NIST), 100 Bureau Drive, Gaithersburg, MD campus.

Delivery shall be completed using FOB destination delivery terms.

INSTALLATION

The Contractor shall install the instruments in Building 221 at NIST Gaithersburg, MD. Installation shall include, at a minimum, uncrating/unpacking of all equipment, set-up and hook-up of the instrument, start-up, demonstration of specifications, and removal of all trash. The Contractor shall demonstrate that the instrument is running in accordance with the System Requirements above. The Contractor shall provide all samples required for on-site demonstration of the of all specifications Identified herein.

Installation shall take place between 8:30 am and 5:00 pm Eastern Time, Monday through Friday, except

Federal Holidays (hereinafter “normal duty hours”) and shall be coordinated with the NIST Technical Point of

Contact (TPOC) via the Contracting Officer’s Representative (COR). Installation shall be completed no later than one month from the date of delivery.

TRAINING

The Contractor shall conduct training at NIST, Gaithersburg, MD, for up to ten NIST personnel covering normal operation, system/solution functions, data administration, troubleshooting, and routine maintenance.

Training shall be provided during normal duty hours and shall be coordinated with the NIST TPOC via the

COR, to ensure maximum availability of NIST personnel. The training shall be completed no later than 30 days after successful completion of installation and demonstration of specifications.

WARRANTY

The Contractor shall provide a one year warranty to commence after successful completion of delivery, installation, demonstration of specifications, training, and acceptance of the instrument by the government. The warranty shall include unlimited repair visits in the event to of instrument failure during normal duty hours. The

Contractor shall cover expenses required for repairs, including parts, labor, travel, and per diem.

GENERAL INFORMATION

Security: NIST is a restricted campus. An identification badge is required for access for entry into buildings and also is shown to the armed Security Police when entering the campus. The Government will submit the name of a contractor employee to the NIST Office of Security in order for a contractor employee to enter the

NIST campus to perform on-site preventive maintenance or repairs of the instrument.

Identification Badges: Contractor employees shall comply with NIST identification and access requirements.

The Contractor employee is responsible for absences due to expired identification and access documents. Each

Contractor employee shall wear a visible identification badge provided by the NIST Security Office. The badge must show the full name, title, and if required by NIST, the words “Contractor” in front. The Contractor employee shall turn in the NIST identification badge and vehicle pass to the TPOC, or Contracting Officer (CO) upon termination of their services under this contract.

Vehicle Registration: All Contractor employees must register their vehicles with the NIST Security Office to gain access to the campus. A valid driver’s license, Government-furnished civilian ID, proof of insurance and current registration must be presented to the NIST Security Office, at which time a NIST vehicle pass will be issued. The pass shall be displayed on the vehicle’s rear view mirror in accordance with instructions. The

Contractor employee shall follow NIST procedures for removal and turn-in of the vehicle pass upon termination of services under this contract.