SOW_BD Cytometer_v2.pdf

3/12/2024, version 2

STATEMENT OF WORK (SOW)

Renewal Maintenance Service Agreement for Becton Dickinson (BD) Flow Cytometers

A. BACKGROUND INFORMATION

The Laboratory of Immune System Biology (LISB) investigates basic aspects of innate and adaptive immune function, with an emphasis on how the body, and more specifically, different cell types within the body discriminate between self and non-self. This discrimination is the crucial mechanism by which the body patrols itself and is able to respond appropriately following exposure to microorganisms or vaccines. Using computational biological approaches coupled with more traditional biological experimentation, the LISB strives to build models of how the mammalian immune system responds to pathogens and vaccines. These models allow us to make informed predictions as to how the body will respond when challenged with various microbes and vaccine formulations. To address these questions, it is imperative to know which cell types are present in a given experimental sample.

The LISB focuses solely on high-tech imaging analysis, advanced microscopy techniques, and cell-type cataloging and tracking during various phases of immune responses. A key component of this work is the use of flow cytometry, whereby preparations of various types of labelled cells are analyzed and cataloged.

The LISB has multiple high-end Becton, Dickinson, and Company (BD) flow cytometry platforms already in use for imaging various samples and this acquisition will augment those capabilities by providing support upstream of imaging and servicing throughout. The flow cytometers are essential for furthering the capabilities of the LISB. The maintenance service agreement is needed to ensure continued operation and fidelity of the flow cytometers.

B. PURPOSE AND OBJECTIVE

The purpose of this acquisition is to provide a maintenance service agreement for flow cytometers, various lasers and accessories manufactured by BD. The cytometer systems consist of the following:

• FACSAria III – 3 Laser System (Serial # P99900014)

• LSRFortessa SORP (Serial # R64717700196)

• FACS Flow Supply System (Serial # N3492775405)

• High Throughput Sampler (Serial # R647701000401)

• LSRFortessa SORP (Serial # R64717700194)

• FACS Flow Supply System (Serial # N3492775418)

• High Throughput Sampler (Serial # R647701000415)

• LSRFortessa SORP (Serial # H64717700055)

• FACS Flow Supply System (Serial # N3332)

• LSRFortessa SORP (Serial # H64717700104)

• FACS Flow Supply System (Serial # N3492774233)

• High Throughput Sampler (Serial # R647701000045)

• FACSymphony A3 (Serial # R66093700076)

• FACS Flow Supply System (Serial # N3492775746)

• FACSymphony A3 (Serial # R66093700215)

• FACS Flow Supply System (Serial # 349277N0263)

These cytometers are constantly in use throughout the day and if were put out of action due to the lack of maintenance or mechanical failure, the ability of the investigators to conduct their research would be severely handicapped. Each of the instruments support multiple experiments each day, and each instrument is fully utilized. Due to the heavy usage of the BD cytometers, they must be repaired, recalibrated, and returned to operation as soon as possible after failure. If systems were put out of action due to lack of maintenance or mechanical failure, the ability of the investigators in the LISB to conduct their research would be severely compromised. These unique parts and system integrity are required to maintain the highest quality of these cytometers. To this end, the LISB requires a maintenance service agreement in place in the event the equipment should fail tolerances and are required by a service engineer. In addition, the maintenance service agreement provides a complete preventive maintenance program, which have proven to be the most efficient and reliable method to maintain research data quality.

C. SCOPE

The contractor shall perform preventive, remedial maintenance and repair services to maintain the BD equipment in good working condition in accordance with the equipment manufacturer's specifications.

D. CONTRACTOR REQUIREMENTS:

The Contractor shall provide services coverage for the Flow Cytometers, various lasers, and accessories, that includes the following:

• Two (2) Preventive Maintenance (PM) Inspections to be performed during twelve-month period

• Two (2) Preventative Maintenance (PM) Kits

• Software revisions & proprietary software updates

• Unlimited service visits, by guaranteed original equipment manufacturer (OEM) technicians, Monday – Friday

• Unlimited guaranteed OEM replacement service parts, components, or modules necessary for repairs, excluding third party items and consumables

• Unlimited telephone support for instruments reagents, and applications will be provided at no additional charge

• 48-hour priority response to a request for emergency on-site service Monday- Friday, Monday through Friday, excluding holidays

• Service and parts must be compliant with Biosafety Level 2

E. CONTRACTOR SUPPLIED MATERIALS

The Contractor shall provide all necessary parts and equipment necessary to perform repair and planned maintenance of the above equipment.

F. GOVERNMENT FURNISHED MATERIALS:

Government furnished materials are not provided under this contract.

G. REPORTING REQUIREMENTS AND DELIVERABLES:

Technical support and remedial repair as needed, annual preventative maintenance, and reporting document of service after PMs and repairs are completed.

H. PERIOD OF PERFORMANCE (POP):

The period of performance is April 1, 2024 – March 31, 2025

I. INSPECTION AND ACCEPTANCE:

a) All work will be inspected and approved by the person designated by the lab chief of each lab at the completion of any repairs and at the completion of the annual maintenance.

b) All work will be completed in accordance with industry standards.