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TOBACCO ANALYSIS AND ENGINEERING LABORATORY SERVICES Federal contract opportunity
Solicitation number
FDA-20-1236379
Issued by
Department of Health and Human Services Food and Drug Administration

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This document contains an appendix listing 93 harmful and potentially harmful constituents (HPHCs) to be tested under an indefinite-delivery/indefinite-quantity (IDIQ) multiple award contract. The related federal contract opportunity solicitation seeks proposals for tobacco analysis and engineering laboratory services. Questions regarding the solicitation are due by October 27, 2021, and proposals are due by November 15, 2021. The solicitation number is FDA-20-1236379 and the agency is the Department of Health and Human Services Food and Drug Administration. Offerors should include the solicitation number in the subject line of any questions or proposals submitted.

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Attachment 5 Class Deviation 2020-02.pdf PDF
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Text version

Reference No. FDA-21-SSN-1236379

Appendix A: List of HPHCs to Be Tested Under This IDIQ

1. Acetaldehyde

2. Acetamide

3. Acetone

4. Acrolein

5. Acrylamide

6. Acrylonitrile

7. Aflatoxin B1

8. 4-Aminobiphenyl

9. 1-Aminonaphthalene

10. 2-Aminonaphthalene

11. Ammonia

12. Anabasine

13. o-Anisidine

14. Arsenic

15. A-a-C (2-Amino-9H-pyrido[2,3-b]indole)

16. Benz[a]anthracene

17. Benz[j]aceanthrylene

18. Benzene

19. Benzo[b]fluoranthene

20. Benzo[k]fluoranthene

21. Benzo[b]furan

22. Benzo[a]pyrene

23. Benzo[c]phenanthrene

24. Beryllium

25. 1,3-Butadiene

26. Cadmium

27. Caffeic acid

28. Carbon monoxide

29. Catechol

30. Chlorinated dioxins/furans

31. Chromium

32. Chrysene

33. Cobalt

34. Coumarin

35. Cresols (o-, m-, and p-cresol)

36. Crotonaldehyde

37. Cyclopenta[c,d]pyrene

38. Dibenz[a,h]anthracene

39. Dibenzo[a,e]pyrene

40. Dibenzo[a,h]pyrene

41. Dibenzo[a,i]pyrene

42. Dibenzo[a,l]pyrene

43. 2,6-Dimethylaniline

44. Ethyl carbamate (urethane)

45. Ethylbenzene

46. Ethylene oxide

47. Formaldehyde

48. Furan

49. Glu-P-1 (2-Amino-6-methyldipyrido[1,2-a:3’,2’-d]imidazole)

50. Glu-P-2 (2-Aminodipyrido[1,2-a:3’,2’-d]imidazole)

51. Hydrazine

52. Hydrogen cyanide

53. Indeno[1,2,3-cd]pyrene

54. IQ (2-Amino-3-methylimidazo[4,5-f]quinoline)

55. Isoprene

56. Lead

57. MeA-a-C (2-Amino-3-methyl)-9H-pyrido[2,3-b]indole)

58. Mercury

59. Methyl ethyl ketone

60. 5-Methylchrysene

61. 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)

62. Naphthalene

63. Nickel

64. Nicotine

65. Nitrobenzene

66. Nitromethane

67. 2-Nitropropane

68. N-Nitrosodiethanolamine (NDELA)

69. N-Nitrosodiethylamine

70. N-Nitrosodimethylamine (NDMA)

71. N-Nitrosomethylethylamine

72. N-Nitrosomorpholine (NMOR)

73. N-Nitrosonornicotine (NNN)

74. N-Nitrosopiperidine (NPIP)

75. N-Nitrosopyrrolidine (NPYR)

76. N-Nitrososarcosine (NSAR)

77. Nornicotine

78. Phenol

79. PhIP (2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine)

80. Polonium-210

81. Propionaldehyde

82. Propylene oxide

83. Quinoline

84. Selenium

85. Styrene

86. o-Toluidine

87. Toluene

88. Trp-P-1 (3-Amino-1,4-dimethyl-5H-pyrido[4,3-b]indole)

89. Trp-P-2 (1-Methyl-3-amino-5H-pyrido[4,3-b]indole )

90. Uranium-235

91. Uranium-238

92. Vinyl acetate

93. Vinyl chloride

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