18RQ0282-SolicitationInstructions-AMENDMENT_0003.pdf

SOLICITATION SB134118RQ0282 AMENDMENT 0002

NEXT-GENERATION DNA SEQUENCING SERVICES

This is a combined synopsis/solicitation for commercial services prepared in accordance with the format in FAR Subpart 12.6 – Streamlined Procedures for Evaluation and Solicitation for Commercial Items, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; quotations are being requested, and a separate written solicitation document will not be issued. This solicitation is being issued under the authority of FAR Part 13.5 Simplified Procedures for Certain Commercial Items.

This solicitation is a Request for Quotations (RFQ) to establish a single award Blanket Purchase Agreement (BPA). The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular (FAC) 2005-97 effective 01/24/2018.

The associated North American Industrial Classification System (NAICS) code for this procurement is 541990 with a small business size standard of $15 Million. This acquisition is being procured as a 100% Small Business Set-Aside. Only quotes submitted by qualified small business concerns will be considered for award.

The National Institute of Standards and Technology (NIST) in conjunction with The Joint Initiative for Metrology in Biology (JIMB) is working to develop technology, standards and applications of DNA barcodes using Next Generation Sequencing. JIMB is located at the National Institute of Standards and Technology (NIST) in Gaithersburg, MD and at Stanford University, Palo Alto, CA.

Period of Performance:

The period of performance for all line items shall be in accordance with the following:

Base Year: 12 months from time of award.

Option Year One: One year after the expiration of the Base Year.

Option Year Two: Two years after the expiration of the Base Year.

The total period of performance shall not exceed three (3) years after award.

Future BPA calls will be solicited directly from the awardee of the BPA resulting from this solicitation.

The total cumulative ceiling for all BPA Calls awarded under the BPA resulting from this solicitation is $650,000.

EVALUATION CRITERIA AND BASIS FOR AWARD

The Government intends to award a single BPA from this solicitation to the responsible Contractor whose quotation, conforming to the solicitation, will provide the best value to the Government, price and other factors considered.

In addition to price, the following factors shall be used to evaluate quotations:

1. Past Performance.

2. Prior Experience

3. Technical Approach

In determining best value, the non-price factors above are listed in descending order of importance.

Price is significantly less important than the non-priced evaluation factors.

1. Past Performance: Evaluation of past performance will be based on the references provided and/or the Contractor’s recent and relevant procurement history with NIST or its affiliates. Past Performance will be evaluated to determine the overall quality of the product and/or service provided by the Contractor. The Government will evaluate past performance based on Past Performance Surveys and by contacting appropriate references, including NIST references; if applicable. Past performance evaluation will include, but is not limited to: Turn-around time; Number of reads delivered; Quality of reads delivered; and Fidelity of reads delivered. The Government reserves the right to consider information available from any available sources. In the case of a Contractor without a record of relevant past performance or for whom information on past performance is not available, the Contractor will be evaluated neither favorably nor unfavorably.

2. Prior Experience: NIST will evaluate the extent of the Contractor’s prior experience in working with applications of DNA barcodes using Next Generation Sequencing.

3. Technical Approach: NIST will evaluate the extent to which the Contractor’s quote demonstrates their ability to satisfy the requirements in the Statement of Work, ensure work quality, and on-time completion of tasks and deliverables.

PRICE

The quoted prices will be evaluated to determine whether the prices are fair and reasonable in relation to the solicitation requirements. The total evaluated price will be calculated from the combined pricing tables listed below for: TOTAL PRICE for BASE YEAR (Line Item 0001 + Line Item 0002); TOTAL PRICE for OPTION YEAR ONE (Line Item 0003 + Line Item 0004); and TOTAL PRICE for OPTION YEAR TWO (Line Item 0005 + Line Item 0006).

Prices must be entirely compatible with the technical portion of the quotation.

The Government will evaluate quotations for award inclusive of the prices quoted for all optional line items. The Government may determine that a quotation is unacceptable if the option prices are significantly unbalanced. Evaluation of options does not obligate the Government to exercise the options.

NIST intends to evaluate quotes and issue BPAs based on the initial quotes received. Therefore, the Contractor’s initial quote should contain the Contractor’s best terms from a price and technical standpoint. NIST reserves the right to request revised quotes from, or negotiate final BPA terms with, one or more, but not all, Contractors if later determined by the Contracting Officer to be necessary.

Please note that this procurement IS NOT being conducted under the GSA Federal Supply Schedule (FSS) program or another Government-Wide Area Contract (GWAC). If a contractor submits a quotation based upon an FSS or GWAC contract, the Government will accept the quoted price.

However, the terms and conditions stated herein will be included in any resultant BPA, not the terms and conditions of the contractor’s FSS or GWAC contract, and the statement required above shall be included in the quotation;

CONTRACTOR INSTRUCTIONS FOR SUBMISSION OF QUOTATIONS

Quotations shall include the following required submissions:

1. Technical Approach. The Contractor shall provide detailed information demonstrating their understanding the statement of work. Additionally, the Contractor shall provide their draft schedule or process outlining how the Contractor’s Turn-around time, Number of reads that can be delivered, the quality of reads delivered, and the Fidelity of reads delivered to meet all deliverables and deadlines.

2. Prior Experience. The Contractor shall provide detailed information on their organization’s work experience in DNA Sequencing for the past three (3) years. The Contractor shall demonstrate how their prior experience relates to the SOW requirements.

3. Past Performance. The Contractor shall provide past performance information regarding up to three (3) relevant contracts over the past three (3) years with federal, state or local governments, and international and commercial customers. The information shall describe contracts of a similar type and scope as the current requirement. If the contractor intends to use another firm for substantial portion of this requirement (i.e., >20% of the total level of effort), that firm’s past performance information must also be provided. If the Contractor has no relevant past performance it must include a statement to that effect. The description of each contract described in this section shall provide the following information, as applicable:

a. Contract Number

b. Description of work performed and relevance to solicitation requirements. Specifically, the contractor shall describe: Turn-around time; Number of reads delivered; Quality of reads delivered; and Fidelity of reads delivered.

c. Period of Performance

d. Point of Contact Information (name, email, phone number) for the client reference

4. Price. Contractors shall provide a Firm Fixed Rate for library construction, quality control and sequencing as detailed below in Line Items 0001, 0002, 0003, 0004, 0005 and 0006. Please provide your price quotes based on these total estimates of work per year for the BPA.

Amplicon Sequencing o Anticipated call orders will be for 100 lanes of sequencing. Samples will be sent in batches with the minimum number of lanes needing to be run at once being one and a maximum of 16 lanes. Batches will be processed until the contract is completed.

Whole-Genome Sequencing o Anticipated call orders will be for sequencing of 30 samples (assume whale or human genome, 3 Gb). Samples will be sent in batches with the minimum number of samples being one and a maximum of 30 samples. Batches will be processed until the contract is complete.

3 samples Chromium library preparation and 40x/sample sequencing (120

Gb/sample) 27 samples Illumina library preparation and 15x/sample sequencing (45

Gb/sample)

Line Item 0001, 0002, Base Year: The Contractor shall provide Next Generation DNA Sequencing Services for JIMB co-located at Stanford University and NIST in Gaithersburg.

Line Item 0001: Amplicon Sequencing (In accordance with the Statement of Work)

Price per Lane

Quantity (for evaluation purposes only)

Total Price

0001a: Quality Control $________ 100 Lanes $_________ 0001b: Sequencing $________ 100 Lanes $_________

Total Price for Line Item 0001 $_________

Line Item 0002: Whole-Genome Sequencing (In accordance with the Statement of Work)

Price per Sample

Quantity (for evaluation purposes only)

Total Price

0002a: Chromium Library Construction $________ 3 Samples $________ 0002b: Illumina Library Construction $________ 27 Samples $________ 0002c: Library Quality Control $________ 30 Samples $________ 0002d: Sequencing $________ 120 Gb Chromium/Samples $________ 0002e: Sequencing $________ 45 Gb Illumina/Samples $________ Total Price for Line Item 0002 $________

TOTAL PRICE for BASE YEAR (Line Item 0001 + Line Item 0002) $__________

Line Item 0003, 0004, Option Year One: The Contractor shall provide Next Generation DNA Sequencing Services for JIMB co-located at Stanford University and NIST in Gaithersburg.

Line Item 0003: Amplicon Sequencing

Price per Lane

Quantity (for evaluation purposes only)

Total Price

0003a: Quality Control $________ 100 Lanes $_________ 0003b: Sequencing $________ 100 Lanes $_________

Total Price for Line Item 0003 $_________

Line Item 0004: Whole-Genome Sequencing

Price per Sample

Quantity (for evaluation

0004a: Chromium Library Construction $________ 3 Samples $________ 0004b: Illumina Library Construction $________ 27 Samples $________ 0004c: Library Quality Control $________ 30 Samples $________ 0004d: Sequencing $________ 120 Gb Chromium/Samples $________ 0004e: Sequencing $________ 45 Gb Illumina/Samples $________ Total Price for Line Item 0004 $________

TOTAL PRICE for OPTION YEAR ONE (Line Item 0003 + Line Item 0004) $__________

Line Item 0005, 0006, Option Year Two: The Contractor shall provide Next Generation DNA Sequencing Services for JIMB co-located at Stanford University and NIST in Gaithersburg.

Line Item 0005: Amplicon Sequencing (In accordance with the Statement of Work)

Price per Lane

Quantity (for evaluation purposes only)

Total Price

0005a: Quality Control $________ 100 Lanes $_________ 0005b: Sequencing $________ 100 Lanes $_________

Total Price for Line Item 0005 $_________

Line Item 0006: Whole-Genome Sequencing

Price per Sample

Quantity (for evaluation

0006a: Chromium Library Construction $________ 3 Samples $________ 0006b: Illumina Library Construction $________ 27 Samples $________ 0006c: Library Quality Control $________ 30 Samples $________ 0006d: Sequencing $________ 120 Gb Chromium/Samples $________ 0006e: Sequencing $________ 45 Gb Illumina/Samples $________ Total Price for Line Item 0006 $________

TOTAL PRICE for OPTION YEAR TWO (Line Item 0005 + Line Item 0006) $_________

5. Terms and Conditions If the Contractor objects to any of the terms and conditions contained in this solicitation, the contractor shall state “The terms and conditions in the solicitation are acceptable to be included in the award document with the exception, deletion, or addition of the following:” [Contractor shall list exception(s) and rationale for the exception(s)]. It is the sole responsibility of the Contractor to identify in their quote any exceptions to the terms and conditions of the solicitation. If the contractor does not include such a statement, the submission of a quotation in response to this solicitation will be regarded as the Contractor’s acceptance of the Government’s terms and conditions for inclusion into the resultant Blanket Purchase Agreement.

6. Required Provisions A completed version of all required solicitation provisions (see attached provisions/clauses document – required submissions highlighted in blue).

7. Contractor Identifying Information The DUNS number for the Contractor’s active System for Award Management (SAM) registration.

8. Socioeconomic Status Representation If the Contractor’s representations and certifications in SAM.gov do not reflect the NAICS code governing this solicitation, Contractor must submit documentation that they are a small business under the NAICS code governing this solicitation.

DUE DATE FOR QUOTATIONS PER AMENDMENT 0002

All quotations must be submitted via e-mail to Harry Brubaker, Contract Specialist at Wendy.Paulo@nist.gov . Submission must be received not later than NOON 12:00 PM Eastern Standard Time, Monday, May 7, 2018. A quotation shall be considered received when it is received in the electronic inbox of Harry Brubaker not later than the date and time identified herein.

mailto:Wendy.Paulo@nist.gov

All questions regarding this notice must be submitted via e-mail to Harry.Brubaker@nist.gov by 11:00 AM Eastern Standard Time on Wednesday, March 21, 2018. Questions submitted after this date may not be addressed by the Government prior to the quotation submission deadline.

In the event of a Government Shutdown during the Solicitation time frame, the Solicitation will be amended accordingly upon the Government’s returning to operations to extend the questions and/or quotation submission deadlines by the length of time of the Government shutdown.

PROVISIONS AND CLAUSES

The provisions and clauses applicable to this solicitation can be found under Applicable Provisions and Clauses. The full text of a FAR provision or clause may be accessed electronically at www.acquisition.gov/far.

ATTACHMENTS:

The following attachments apply to this solicitation:

1. The Statement of Work

2. Applicable Provisions and Clauses mailto:Harry.Brubaker@nist.gov http://www.acquisition.gov/far