SATPC0041693 Tab 04 4 SOW.pdf
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- Screen candidate subjects for eligibility to participate in a spaceflight study Federal contract opportunity
- Solicitation number
- 80NSSC26937596Q
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Statement of Work Summary
This Statement of Work describes contracted services for the "SANS Cuff" efficacy study, a Human Research Program initiative testing thigh cuffs as a countermeasure against Optic Disc Edema (ODE) during spaceflight missions. The contractor shall screen no more than 15 candidate subjects for eligibility using artificial intelligence prediction tools trained on spaceflight ocular coherence technology (OCT) images from previous astronaut missions. The vendor will analyze anonymous OCT image datasets provided by NASA Johnson Space Center's Cardiovascular and Vision Laboratory (CVL) to predict whether subjects will develop Spaceflight Associated Neuro-ocular Syndrome (SANS) in-flight and calculate predicted changes in total retinal thickness (ΔTRT). Analysis results will be delivered to CVL on a per-mission basis at a rate of 2-3 subjects per mission, not exceeding 5 subjects screened annually, with testing completed in a timely manner to support SANS milestones.
Performance will be conducted at the University of California, San Diego in San Diego, California. The contract period extends from August 1, 2026 through July 31, 2028 for the base year, with two optional renewal years: August 1, 2028 through July 31, 2029 (Option Year 1) and August 1, 2029 through July 31, 2030 (Option Year 2).
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| File | Type | Posted |
|---|---|---|
| SATPC0041693 Tab 07 Capability Statement.pdf |
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Text version
Statement of Work
1. Objective/Requirements
The Human Research Program funded the study, “Flight Thigh Cuff” or better known by Ops Nom name, “SANS Cuff.” This study will test the efficacy of using thigh cuffs as a countermeasure against Optic Disc Edema (ODE) throughout a spaceflight mission. To determine whether a crewmember might develop ODE in flight and thus be a suitable candidate to participate in this efficacy study, one of the eligibility criteria will be whether an AI tool predicts that subject will develop SANS (Spaceflight Associated Neuro-ocular syndrome) in-flight and whether the predicted change in total retinal thickness is above a predetermined threshold.
Vendor shall screen no more than 15 candidate subjects for eligibility to participate using AI prediction tools that have been trained using spaceflight ocular coherence technology (OCT) images obtained from astronauts during previous spaceflights.
2. Characteristics, Scope, Specs
The contractor shall perform the following duties:
• OCT image datasets o Anonymous OCT Datasets will be provided to the vendor by the NASA Johnson
Space Center Cardiovascular and Vision Laboratory (CVL) o The vendor will analyze the provided images using an AI program to predict
▪ Development of SANS: yes/no
▪ Predicted ∆TRT o Results will be provided to the CVL.
• Complete testing in a timely manner to support SANS milestones
3. Deliverables
Screening results will be delivered to the NASA Johnson Space Center CVL on a per mission basis (2-3 subjects per mission, not to exceed screening of 5 subjects per year).
4. Place of Performance
University of California, San Diego in San Diego, California
5. Period of Performance
Year 1: 8/1/26-7/31/28
Option year 1: 8/1/28- 7/31/29
Option year 2: 8/1/29-7/31/30
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