SAM_-_Pre-Solicitation__75N94025Q00232_1.pdf

75N94025Q00232

INTRODUCTION

THIS IS A PRE-SOLICITATION NON-COMPETITIVE (NOTICE OF INTENT) SYNOPSIS TO AWARD A CONTRACT

OR PURCHASE ORDER WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION.

The National Institutes of Health, National Institute of Child Health and Development (NICHD), in support of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), intends to award a purchase order without providing for full and open competition to WATERS TECHNOLOGIES CORPORATION.

for Repair and Service Contract on Waters Liquid Chromatography/Mass Spectrometry Instrument.

BACKGROUND

The NIDDK Molecular and Clinical Nutrition Section research determines optimal nutrition in health, disease, and disease treatment using vitamin C (ascorbic acid) as a model nutrient. Research examines how specific nutrient function occurs in relation to nutrient concentration, in vitro (in cells and organelles) and in vivo (animals and people). The lab has a LC/MS/MS [liquid chromatography/mass spectrometry/mass spectrometry] system that is essential for measurement of vitamin C (ascorbic acid) and its product dehydroascorbic acid in health and disease in clinical and cellular samples. This system is the only one of capable of direct measurement dehydroascorbic acid, as well as vitamin C. Quantitation of both compounds together by direct measurement is necessary to understand the roles of vitamin C in health and disease in humans. Without this system, the lab will not be able to proceed to understand the roles of these two related vitamers in diabetes in humans and in other diseases. At this time the lab is the only one in the world that can do these measurements, and the lab can only do so by using this particular instrument. The instrument is in need of repair service and preventive maintenance to keep it in operation because it is an essential component of upcoming clinical bench to bedside research proposals.

JUSTIFICATION

Our current Waters Xevo TQ-S micro mass spectrometer instrument is the only instrument that can simultaneously detect both vitamin C and its oxidized product dehydroascorbic acid. Service of this instrument to restore it to operational ability is the only way that the lab can continue measure vitamin C and dehydroascorbic acid together in clinical samples, which is essential to our research mission. There is no other instrument that will suffice, and for the measurements to be possible, the instrument has to be in working order. The instrument is proprietary to Waters Technologies, therefore they have the unique capabilities to service this instrument properly and provide specialty replacement parts. This ability cannot be replicated by another company or alternative service. Waters is the manufacturer of the instrument and does not have other resellers to provide services or repairs.

NORTH AMERICAN INDUSTRY CLASSIFICATION SYSTEM (NAICS) CODE

The intended procurement is classified under NAICS code 811210 Electronic and Precision Equipment Repair and Maintenance, size standard in number of dollars $34.0

REGULATORY AUTHORITY

The resultant contract will include all applicable provisions and clauses in effect through the Federal Acquisition Regulation (FAR) Circular (FAC) 2025-05 effective 08/07/2025. This acquisition is conducted under the procedures as prescribed in FAR subpart 13-Simplified Acquisition Procedures at an amount not exceeding the simplified acquisition threshold ($250,000) and FAR Subpart 12- Acquisition of Commercial Items.

PRE-SOLICITATION NON-COMPETITIVE (NOTICE OF INTENT) SYNOPSIS

75N94025Q00232

STATUTORY AUTHORITY

This acquisition is conducted under the authority of FAR 13.106(b)(1) Soliciting from a single source - For purchases not exceeding the simplified acquisition threshold.

PLACE OF DELIVERY

NIH/NIDDK

Building 10 Room 4D52, MSC 1372 10 Center Drive Bethesda MD 20892-1372

DESCRIPTION OF REQUIREMENT

Repair and preventive maintenance of LC/MS/MS system so that measurements can resume of dehydroascorbic acid and vitamin C. Installation/repair must be conducted so that equipment is functional.

Effective date of repair service is no more than 8 weeks after purchase order is awarded.

Requirements of purchase:

Repair of LC/MS/MS system.

Replacing first quadropole (detector) due to fouling.

Replacing hardward degassing chip.

Preventive maintenance plan to keep a complex system running.

12-month Service agreement in event that there is product wear and/or malfunction.

Vendor shall provide a maintenance agreement to be in place for one year after effective date of award

Period of Performance: 1 Year from Date of Award

CLOSING STATEMENT

This synopsis is not a request for competitive proposals. However, interested parties may identify their interest and capability in response to this notice and may submit a capability statement, which shall be considered by the agency. Responses to this notice shall contain sufficient information to establish the interested parties’ bona-fide capabilities for fulfilling the requirement. A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement.

All respondents must have an active registration in the System for Award Management (SAM) www.sam.gov. All responses to this notice shall be submitted electronically by 5:00 PM Eastern Standard Time, on September, 19th, 2025 to jacob.balenson@nih.gov and shall include pre-solicitation # 75N94025Q00232 in the subject line.